1. P08042: Smoking Machine with Integrated Lung Cast for Particle Deposition of Smoke in the Human Lung Joe LeittenProject Manager Edward Harding Lead Engineer Woo Young ChoiLead Engineer Adam DavenportLead Engineer John KoeppelMechanical Engineer Kenya AthillElectrical Engineer Svilen Piralkov Computer Engineer Clinton HaydukeMechanical Engineer Mike Dizhgalvis Mechanical Engineer Yi Fan ZhangMechanical Engineer Sponsor: Dr. Risa Robinson (American Cancer Society)

2. Project Description  Machine to smoke cigarettes for the

3. Design Concept

4. Risk Assessment

5. Current Project State

6. MSD II Project Timeline

7. Customer Requirement  Machine Team 1. Meet Required ISO Document Specifications 1. Flameless Ignition 2. Flow pattern 3. Length of cigarette 2. Sealed from outside environment 3. Capable of Expansion in Future 4. Quick & Easy Assembly/Disassem bly 5. Modular Lung Team 1.Capable of Removing Smoke Deposition 2.Low-Cost 3.Easy removal and installation from Machine 4.Rigidity 5.Pressure sensors to obtain pressure data

8. Machine Layout

10. 5 Cigarette Layout 1 2 3 4 1.Cigarette Holder 1.Made from Aluminum 6061 2.Quick Disconnects to ¼” NPT 1.Nickel Plated~$4.00 per piece 2.Stainless Steel~$ 42.00 per piece 3.Plenum 1.2 ½” Cast Acrylic 4.Control Valve 1.Clippard Direct acting 2-way, normally closed 5.Cigarette Holder Assembly 1.Made from Aluminum 6061

11. Control Valve Electronic Control Valve 180 Max PSI 32°F to 140°F Operating Temperature Range 6.7 SCFM @ 100 PSIG Clippard ¼” NPT Direct Acting 2-Way Solenoid Valve, 12 VDC Wire Leads MME-2QDS-W012 $19.70

12. Lighter Layout 1 2 3 4 5 6 1.Linear Actuator 1.Firgelliauto 4” Actuator 2.Roller Guide 1.Structural Tubing T-Slot Guide 3.Structural Tubing 1.1” x 1” Square Structural Tubing 4.Cigarette Lighter Assembly 1.Material: Aluminum 6061 5.Linear Actuator Bracket 1.Firgelliauto Recommended for Actuator 6.Cigarette Lighter 1.Made from Car Cigarette Lighter

13. Flameless Ignition  Flameless ignition must be used. Shall light at first attempt without touching or pre- charring cigarette. Preliminary Tests: 1.Using a vice tested distance to ignite cigarette ~ ¼” 10 seconds to max temp.

14. Cigarette Length Detection 1.OMEGA Miniature Low-Cost Non- Contact Temperature Sensor/Transmitter 2.Temperature Range : 0 to 400 °F or 300 to 1000 °F 3. Cigarette Burns at ~600 °F 4.Detects when cigarette reaches 23 mm specification 5.Cone can theoretically be focused using reflective material over tip 6.24 Volt DC

15. Machine Layout

16. Humidifier Chamber 1 2 3 4 5 6 1.Control Valve 1.Clippard Direct acting 2-way, normally closed 2.Latching System 3.Humidity Chamber 1.Cast Acrylic Tubing 4.Humidification Sensor 5.Quick Disconnect Tube to Pipe Fitting 6.Closed Cell Sponges Preliminary Test Results: 1.Humidity must be > 90% 2.Set up two different tests 1.Placed wet sponges instead with heater around outside (~65%) 2.Let water stand in bottom with heater on outside (~72%)

17. Sensors Parameters Tolerances Operating Temperature -40 to +85 C Supply Voltage 4 to 5.8 volts Operating Humidity 0-100%+/- 3.5% RH Linearity0-100%+/- 3.5% RH Temperature Accuracy+/- 0.40C Typical Cost~$40 Omega Part Number: PX4200-015GI ParametersTolerances Operating Pressure 0 to 15 psi Supply Voltage 13 to 36 VDC Accuracy +/-.25% Full Scale Repeatability+/-.1% Full Scale Response Time10 ms Cost$295 Honeywell Part Number: HIH 4000 Series

18. Combined Assembly

19. Machine Layout

20. Back End Assembly 1 2 3 4 1.Pressure Sensor 1.Omega silicone on sapphire pressure transducer 2.Flow Meter 1.Brooks Delta Class MFM w/Flow Control 3.Pall Polycarbonate 47mm Filter 4.Condenser 5.¼” NPT Pipe T Fitting 5

21. Flow Meter Brooks Delta Class Mass Flow Meter Part Number: SLA5850S1BAB0B2B1L3VBAA ParametersTolerances Accuracy +/- 1% of full range, 0.2% below 20% full scale Temperature0 to 60C max Power Requirements0-5Volts, 4-20mA Power supplySingle sided 15 DC, +/-5% Flow range0.05 to 3 kg/hr Connection¼’’ male VCR Pressure5-50psi Cost~$1900

22. Catch-All Filter Pall Polycarbonate 47mm Filter Holder Price: $75.94

23. Machine Enclosure Aluminum T-Slotted Framing Approx. $26 per 8 feet All Welded Steel Workbench 60” x 36” x 36” $370

24. Complete Machine

25. Lung Cast Front ViewRear View

26. Lung Cast – Side Views

27. High Risk Items Achieving Humidity Requirement (Air must reach 90% Relative Humidity) (Machine) Bell-Curve Flow Profile using Brooks Flow Meter (Machine) Hardening Lung Cast without changing electrostatic properties (Lung Cast) Maintain pressure throughout entire flow path (Machine) Keeping Overall Machine clean from smoke deposits (Machine) Meeting Environmental Health & Safety requirements (Machine) Assuring cigarette becomes lit after cigarette lighter becomes energized (Machine) Last branch of bronchi tend to have flash build up (Lung Cast) Rough surface finish (Lung Cast) Smoke interference with all sensors and valves (Machine & Lung Cast)