1. Disorders of Growth

2. Introduction:  Tumor – Swelling / new growth / mass  Two types of growth disorders:  Non-Neoplastic  Secondary / adaptation due to other cause.  Neoplastic.  Primary growth abnormality.

3. Non-Neoplastic Proliferation: *Controlled & Reversible  Hypertrophy – Size  Hyperplasia – Number  Metaplasia – Change  Dysplasia – Disordered

4. Neoplastic Proliferation: Uncontrolled & Irreversible*  Benign  Localized, non-invasive.  Malignant (Cancer)  Spreading, Invasive.

5. Pathogenesis – Smoke - Lung Dis.

6. LVH in Chronic Hypertension: Left Ventricular Hypertrophy

7. Goitre – Iodine Deficiency

8. Endometrial Hyperplasia:

9. Benign Prostatic Hyperplasia:

10. Ovary - Cytadenoma

11. Adenomatous polyp

12. Polyclonal Monoclonal Normal Adaptation Benign Malignant Mechanism of Growth Disorders

13. Nomenclature: Cell of origin + Suffix (Oma)  Fibroma  Osteoma  Adenoma  Papilloma  Chondroma

14. Multiple Adenoma colon:

15. Fibroid uterus: (leiomyoma)

16. Lipoma Intestine: