1. tuberculosis - the opportunity in our lifetime Dr. Lucica Ditiu | Executive Secretary | Stop TB Partnership 09.April.2013 | Brussels, Belgium

2. the achieve ments GF funding provided TB treat to 9.7 mil people Contributed to increase of the case detection from 43% to 65% and treatment success from 67% to 87% in the 22 high burden countries

3. the achieve ments

4. 125 107 92 79 68 58 50 43 37 32 28 24 20 18 15 13 11 10 9 8 Belgium Global 8 / 100k / 100k 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2230 2250 year TB incidence the burden

5. Population of Brussels 1.1 MILLION People who died of TB in 2011 1.4 MILLION the burden

6. 1.4 MILLION People who died of TB in 2011 the burden

7. 1.4 MILLION 9 MILLION estimated TB cases 6 MILLION cases diagnosed and treated MDR-TB 570,000 estimated cases that go undiagnosed & untreated the burden 59,000 MDR-TB cases diagnosed and treated

8. the lessons learned lives saved due to TB & HIV integration (2005-2011) 1.5 MILLION 25 fold increase cases detected & treated due to prioritized interventions in vulnerable populations 25x doubled detection & treatment through engagement with TB communities

9. Cost effective TB interventions are the 4 th most cost effective among interventions to control disease (Copenhagen Consensus 2012) Cost per DALY gained varies between US$ 5-200 for first line treatment and US$ 90-365 for second line treatment Costs are being driven down: diagnostics and second line drugs New tools Gene Xpert: new rapid diagnosis for TB and Rif resistance rolled out (1,000 machine worldwide) First new anti-TB drug in 50 years New drug regimens for shorter treatment duration and fewer pills in clinical trials 12 vaccine candidates in the pipeline Strategic investment guidance Sustainable outlook with strong co-investment from countries Potential of mobilizing up to 60% of financial needs from domestic resources Opportunity to leverage domestic commitments the potential & tools

10. with the tools and expertise we have today we must accelerate our efforts and investments for tomorrow

11. 1.4 MILLION cases diagnosed and treated MDR-TB 570,000 estimated cases that go undiagnosed & untreated the vision 59,000 MDR-TB cases diagnosed and treated 67896789 cases diagnosed and treated 630,000 diagnosed and treated 9 MILLION estimated TB cases with

12. Potential lives saved with treatment TB TB/HIV MDR-TB the impact potential lives saved with full funding through 2016 6 MILLION

13. 9 MILLION estimated TB cases with 9 MILLION cases diagnosed and treated the vision MDR-TB 630,000 diagnosed and treated a world free of TB

14. thank you