1. Do Now 3/16/15 1.List at least 3 things transported throughout the body by the blood. 2.Describe at least 2 ways the blood regulates the body. 3.Of the blood samples pictured, determine which is oxygenated and which is deoxygenated. Describe how you know.

2. Leukocytes & Platelets

4. Types of White Blood Cells Leukocytes — White Blood Cells or WBCs — Largest sized blood cells — Lowest numbers in the blood (4,500 – 11,000 per microliter) = 1% of formed elements —Formed in the bone marrow and some in the lymph glands —Primary cells of the immune system — Fights disease and foreign invaders http://ww w.giantmicr obes.com/ us/product s/whiteblo odcell.html

5. Types of White Blood Cells White blood cells — Contain nuclei with DNA, the shape depends on the type of cell — Certain WBCs produce antibodies — Life span is from 24 hours to several years —Size is 8-20 micrometers — There are five different types of WBCs 1) Neutrophils 2) Eosinophils 3) Basophils 4) Lymphocytes 5) Monocytes http://ww w.giantmicr obes.com/ us/product s/whiteblo odcell.html

6. Types of White Blood Cells Leukocytes can be divided into two groups. 1)Granulocytes — Contain granules; inclusions in their cytoplasm — Usually have lobulated or segmented nuclei — Neutrophils — Basophils — Eosinophils 2)Agranulocytes — Do not contain granules — Do not have lobulated or segmented nuclei — Monocytes — Lymphocytes

7. Types of White Blood Cells Neutrophils — Account for the highest amount of WBCs [~60%] — Fight off bacterial invaders — Fight off fungal invaders — Take part in phagocytosis Neutrophils look like….. — Nucleus is divided into 2 to 5 segments and stains dark purple (multi-lobed nucleus) — Cytoplasm is pale pink to tan with fine pink-purple granules When do you see them? — High numbers during bacterial infections and inflammation — Present in pus

8. Types of White Blood Cells Eosinophils — Fight off parasitic worm and flukes — Important in allergic reactions — ~ 3 % of WBCs in the blood Eosinophils look like….. — Nucleus is divided into 2 segments — Cytoplasm is pale pink to tan with large orange and red granules When do you see them? — High numbers with parasitic infections

9. Types of White Blood Cells Basophils — Releases histamine in response to an allergic reaction — Seen with inflammation — Lowest number of WBCs in blood [<1%] Basophils look like….. — Nucleus has 2 lobes that stains purple and is difficult to see — Cytoplasm is pale pink –tan but contains large purple/blue-black granules When do you see them? — High numbers during allergic reactions — High numbers during inflammatory reactions

10. Types of White Blood Cells Monocyte — Search for bacteria and viruses — Participate in phagocytosis — Largest of the white blood cells — ~ 6 % of WBCs in the blood Monocytes look like….. — Singular nucleus (convoluted shape); kidney shaped, bean shaped, or horseshoe shaped with a deep indentation — Vacuoles are sometimes present When do you see them? — High numbers during bacterial and viral infections

11. Types of White Blood Cells Lymphocyte — Fight viral infections — Some produce and secrete antibodies — 2 nd most common WBC in blood — ~ 30 % of WBCs in the blood Lymphocytes look like….. — Large, dark staining nucleus, round or oval — Little to no cytoplasm, blue in color — Occasional purple-reddish granules When do you see them? — High numbers during viral infections

12. Platelets Platelets (Thrombocytes) — Not considered a WBC — Function in hemostasis Platelets look like….. — Small about 2-3 micrometers in diameter — Fragments — Stains bluish and usually contains small reddish-purple granules — Oval or round but can have spiny projections —Normal is between 7-20 per field