9. (22%) (15%) (10%) (9%) (40%) (< 10% )

11. Pathology (sputum and bronchial biopsies)

12. Pathophysiology

16. Diagnostic and Therapeutic Approaches

23. Management of Acute of Exacerbation COPD

41. Summary

44. Factors Associated With Increased Risk for Exacerbations

48. Outpatient

50. Antibiotic treatment of acute exacerbations of COPD (Outpatient)

51. Pseudomonas risk factors: - Frequent administration of antibiotics (4 or more courses over the past year) - Recent hospitalization (2 or more days' duration in the past 90 days) - Isolation of Pseudomonas during a previous hospitalization - Severe underlying COPD (FEV1 <50 percent predicted) (Grade 2B)

52. Antibiotic treatment of acute exacerbations of COPD (hospitalized)