1. AMDS Clearing House Dr Jos Perriens Coordinator TCO Unit/HIV, WHO

2. Objectives of the clearing house Collect, consolidate and disseminate strategic information regarding affordability, accessibility, and availability of HIV drugs: data on price and registration In-house Products Global Price Reporting Mechanism - on AMD website Regulatory status database - on AMD website Controlled Medicines (Methadone+buprenorphine+morphine) database - on AMD website API prices - on AMD website Forecasting of global ARV demand - on AMD website PSM Toolbox Clearing house

3. AMDS Information Platform Global Price Repor- ting Mecha- nism APIAPI Regula- tory status Opioïd Sub- stitution Therapy data- base HTMH HT HTM HH H HTM H Fore- casting portal (surveys, back- ground, papers) Treat- ment guide- lines repo- sitory PQ (EMP) Corpo- rate Pricing Policies (MSF) Capacity building tools: PSM Toolbox

4. Improvements currently being implemented in the Global Price Reporting Mechanism [GPRM]

5. Old GPRM

6. New database with more fields: Done Might be revised to accommodate diagnostics Open pluggable architecture: Done Waiting for the validation and normalization algorithms from ANRS New administrative interface: Done Missing publication interface New download interface: In progress New reporting/visualisation interface: In progress Tool deployed (Inetsoft) Database as decision making tool in the public domain end 2011 New GPRM Status

7. Visualization interface Future GPRM Dashboards Data MashupsReports Inetsoft Style Intelligence

10. SOURCES AND PRICES OF ACTIVE PHARMACEUTICAL INGREDIENTS

11. Forecasting antiretroviral demand

12. Opioid substitution therapy and morphine database

13. PROCUREMENT & SUPPLY MANAGEMENT TOOLBOX

14. URL for the different databases Global Price Reporting Mechanism (GPRM): http://www.who.int/hiv/amds/price/hdd/ The Drug Regulatory Status Database: http://www.who.int/hiv/amds/patents_registration/drs/ PSM Toolbox website: http://psmtoolbox.org/en/ SOURCES AND PRICES OF ACTIVE PHARMACEUTICAL INGREDIENTS http://www.who.int/hiv/amds/api.pdf Controlled Medicines: http://www.who.int/entity/hiv/amds/ControlledMedicineDatabase.xls Forecasting antiretroviral demand: http://www.who.int/hiv/amds/forecasting/en/index.html Prequalification Project http://apps.who.int/prequal/

15. Contacts Boniface Dongmo Nguimfack dongmonguimfackb@who.int –Global Price Reporting Mechanism (GPRM) –The Drug Regulatory Status Database –SOURCES AND PRICES OF ACTIVE PHARMACEUTICAL INGREDIENTS –Controlled Medicines –Summary report from the Global Price Reporting Mechanism Vincent Habiyambere habiyamberev@who.int –PSM Toolbox –Forecasting antiretroviral demand –Early warning indicators to prevent stock-out and overstock