1. production antibody SYNNOVE, KEVIN, KRIZIA

2. What is an antibody ? protein that binds to antigens chemicals that stimulate immune responses to foreign proteins and molecules on the surface of pathogens the body produces a vast array of different antibodies, each one binds to a specific antigen

3. Where does antibody production occur? In lymphocytes (white blood cells) B-lymphocytes (or B-cells)  differentiate in the bone marrow T-lymphocytes (or T-Helper Cells)  differentiate in the thymus

4. A B Cell is trigged when it encounters its matching antigen. The B-Cell engulfs the antigen and digests it. how are antibodies created ? 1. 2. BB

5. Antigens from the ruined pathogen are displayed on the surface of the phagocyte (or B-cell), bound to a membrane called MHC protein. 3. I’m a helper t- cell! This combination of antigen and MHC attracts the help of a mature, matching Helper T Cell. B 3. 4. Cytokines secreted by the Helper T cell help the B cell to multiply and mature into antibody producing plasma cells. B

6. 5. Antibodies are secreted. 6. Antibodies then lock onto matching antigens.

7. "AP Biology Bookmarks." Back To the Stevenson Homepage. Web. 30 Sept. 2009.. In short visual summary…

8. And…

9. So what happens after antibodies lock onto pathogens? pathogens more recognizable to phagocytes, so they can easily be engulfed prevents viruses from docking to host cells so that they cannot be taken up by host cells Causes agglutination (sticking together) of pathogens so that they are prevented from entering cells and are easier for phagocytes to ingest.

10. bibliography "AP Biology Bookmarks." Back To the Stevenson Homepage. Web. 30 Sept. 2009. <http://www6.district125.k12.il.us/science/APBIO/apwebsites.html Homepage - ABPI - Resources for Schools. Web. 01 Oct. 2009..