1. Due Monday, September 29th Hardy Weinberg Analysis

2. Case 1 Analysis In your lab book, compare your class data for Case 1:Hardy- Weinberg Equilibrium with your computer model with the same number of individuals. Press F9 a few times to simulate a few different trials. Record all of your observations Describe what you are seeing (qualitative) in your computer model. What forces could be acting upon this? Is it truly in H-W equilibrium? Why or why not?

3. Case 2 Analysis In your lab book, compare your class data for Case 2: Selection after 5 generations with your computer model with 1000 individuals after 5 generations. Press F9 a few times to simulate a few different trials. Record all of your observations Describe your comparison. What causes more change, your class data or the larger sample size?

4. Case 3 Analysis- BONUS Try to model the heterozyote advantage as we performed it in class. This must truly follow the class simulation and it’s all or none for extra credit.

5. Case 4: Independent Investigation In your lab book, you will complete a full investigation. 1. Determine your question (non-random mating, gene flow, mutation). 2. Record your review of literature (text book). 3. Formulate your hypothesis. 4. Record your procedure. This includes: 1. Your scenario for the change 2. Your formula that models that change. 5. Analyze your data 6. Write a brief conclusion.

6. Example scenario… If I were to use natural selection: There is a population of bakerbugs. In Bakerbugs, following the proper rules of “simon says” is dominant (A) and following the new weird rules of “Nibbly Bibble” is recessive (a). All of a sudden, the environment changes. Those who are homozygous recessive and those who are heterozygous survive, but those who are homozygous dominant only survive 25% of the time. You need to express this in a formula in order to model it through the generations.

7. And formula Original formula: A alleles = AA*2+AB B alleles = BB*2+AB New Formula A alleles = (AA*2*.25)+AB (“.25 represents the 25% that survived) B Alleles stays the same Tips- if your formula gives you alleles in a decimal, reformat the cells to round them to a whole number; you can’t have part of an allele in a population.