1. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Genetic Risk of Primary Open-angle Glaucoma: Population-Based Familial Aggregation Study Arch Ophthalmol. 1998;116(12):1640-1645. doi:10.1001/archopht.116.12.1640 Lifetime risk of elevated intraocular pressure (>21 mm Hg) or therapy to lower intraocular pressure. Figure Legend:

2. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Genetic Risk of Primary Open-angle Glaucoma: Population-Based Familial Aggregation Study Arch Ophthalmol. 1998;116(12):1640-1645. doi:10.1001/archopht.116.12.1640 Lifetime risk of cup-disc ratio of 0.7 or higher or asymmetry in cup-disc ratio between both eyes of 0.3 or higher. Figure Legend:

3. Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Genetic Risk of Primary Open-angle Glaucoma: Population-Based Familial Aggregation Study Arch Ophthalmol. 1998;116(12):1640-1645. doi:10.1001/archopht.116.12.1640 Lifetime risk of glaucoma, defined as a visual field defect in combination with a cup-disc ratio of 0.7 or higher or asymmetry in cup- disc ratio of 0.3 or higher. Figure Legend: