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Published byCorey Shaw Modified over 9 years ago
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Pedigree Charts
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Definitions Pedigree: the recorded ancestry of an individual (family tree). Pedigree Chart: a graphic presentation of a family tree that permits patterns of inheritance to be followed for a single trait.
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Pedigree Charts Symbols: MalesFemalesMating Identical Twins Fraternal Twins Affected Individuals Known Heterozygotes Roman numerals represent generations (I, II, III). Arabic numbers represent individuals within a generation. Birth Order: left to right – oldest to youngest
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Pedigree Charts Example: S – short-sighted s - normal vision I II III 1 2 1 1 2 34 5 6 2 3 4 5 6 SsSsss SsSs SsSs SsSs SsSs
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hemophilia has been studied through pedigree charts traced back to a spontaneous mutation in Queen Victoria in the 1800’s. as royal families intermarried, the mutation spread quickly throughout the European royal families
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Let H = normal h = hemophilia XHXhXHXh XHYXHY XHYXHYXhYXhYXHXHXHXH XHXhXHXh or XHYXHY XHXhXHXh XHXhXHXh
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