1. Pedigrees Pick up Handout

2. Pedigrees = “Family Trees” Standard Symbols

4. Blue people of Kentucky B=Normal b=methemoglonemia

5. Royals of Europe: hemophilia

6. Get Handout “How to Construct a Human Pedigree” The affected trait is usually shaded. See the note: N = normal nn = not normal and is shaded

7. See Handout N=Normal n=not normal 1.How many children did parents II-3 and II-4 have? 3 2. What is the sex of the oldest child of parents II-7 and II-8? Male 3. What is the genotype of person I-1? nn because there are affected and not affected offspring

8. See Handout N=Normal n=not normal 4. What is the relationship of the person II-4 to the couple I-1 and I-2? Daughter-in-law

9. Label the generations and individuals  oldest children are on the left GENERATIONS: use Roman Numerals

10. Label the generations and individuals I II III 12 123 12 3 4

11. Label the generations and individuals I II III 12 123 12 3 4 EE and Ee are free lobes ee is attached lobe

12. Label the generations and individuals I II III 12 123 12 3 4 EE and Ee are free lobes ee is attached lobe ee Ee E- Ee

13. Your assignment: Constructing A Pedigree for Your Family 1. Choose one of the traits from the “Variations of a Human Face” 2. Construct at least 3 generations: REQUIRED: Your parents, your grandparents, and your brothers and sisters. Extra Credit for aunts, uncles, and cousins. 8 1/2 by 11 paper Correct symbols DUE MAY 26

14. You cannot use: Eye color, hair color, skin color…these have polygenic traits and are too difficult to do with a simple pedigree That is why we are staying with the simple dominant – recessive traits of the activity “Variations of a Human Face”

15. If you are adopted or are not able to determine a relative…

16. OK to make lines longer to fit people on the chart See how you make a bracket when crossing lines

17. Can we say “Marriage Counseling?”