1. University Organizational Model Teaching Teaching Departments provide stability Departments provide stability Programs can come and go Programs can come and go Research Research Departments provide core Departments provide core Centers give flexibility Centers give flexibility

2. CBB – Computational Biology and Bioinformatics Director John Harer Program Coordinator Jennifer Avery Certificate Students 13 Faculty 48 DGS Jeanette McCarthy Graduates 3 PhD Students 32

3. CBB Elements Admitting Ph.D. Program Admitting Ph.D. Program Spans entire University Spans entire University Centered in IGSP Centered in IGSP Partners with Centers Partners with Centers Financial support from Provost, A&S and SoM Financial support from Provost, A&S and SoM

4. CBB Core Courses CBB 220: Genomic Tools and Technologies CBB 220: Genomic Tools and Technologies CBB 230: Algorithms in Computational Biology CBB 230: Algorithms in Computational Biology CBB 240: Statistical Methods for Computational Biology CBB 240: Statistical Methods for Computational Biology

5. Other CBB Elements Research Rotations Research Rotations 3 in first year, 12 weeks 3 in first year, 12 weeks Independent study or Lab Independent study or Lab At least one biological and one computational At least one biological and one computational Weekly Seminar Weekly Seminar Dual Advisors Dual Advisors

6. CBB Courses

7. Funding NIH T32 Training Grant NIH T32 Training Grant Supports 4 students Supports 4 students Grant originally awarded to fund 8 students Grant originally awarded to fund 8 students Duke Graduate School Duke Graduate School Currently supports 7 students Currently supports 7 students Fills the gap with NIH student funding Fills the gap with NIH student funding IGSP IGSP Provides logistical and programmatic support Provides logistical and programmatic support seminar series, new student recruitment, facilities, faculty and administrative salaries, general program expenses seminar series, new student recruitment, facilities, faculty and administrative salaries, general program expenses

8. Recent Achievements New Students New Students 9 new students matriculated in fall 2008 9 new students matriculated in fall 2008 3 James B. Duke Awardees 3 James B. Duke Awardees 1 Chancellor’s Scholar 1 Chancellor’s Scholar 1 recipient of the Canadian NSERC Fellowship 1 recipient of the Canadian NSERC Fellowship Papers Papers 16 Papers published in 2008 16 Papers published in 2008 1 first author Nature paper 1 first author Nature paper 1 first author Cell paper 1 first author Cell paper

9. Challenges - Faculty Staffing courses Staffing courses Compete with dept priorities Compete with dept priorities Culture in SoM vs Campus Culture in SoM vs Campus Recognition for faculty efforts Recognition for faculty efforts Tenure and promotion Tenure and promotion Annual Evalution Annual Evalution

10. Challenges - Students Recruitment Recruitment Training Training Dealing with wide variety of backgrounds Dealing with wide variety of backgrounds Arranging program elements Arranging program elements Job placement Job placement Academic Academic Industry Industry

11. Goal s for Future Develop Faculty in CB. Develop Faculty in CB. Expand Core Areas – NOT JUST GENOMICS! Expand Core Areas – NOT JUST GENOMICS! Modeling and more areas of biology. Modeling and more areas of biology. Environment (?) ‏ Environment (?) ‏ Integrate with Departmental Missions. Integrate with Departmental Missions.