Mass Spectroscopy As Applied to Organic Molecules By Jim Tyser.

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Presentation transcript:

Mass Spectroscopy As Applied to Organic Molecules By Jim Tyser

M.S. How It Works The physics behind mass spectrometry is that a charged particle passing through a magnetic field is deflected along a circular path on a radius that is proportional to the mass to charge ratio, m/e.

M.S. How It Works A high energy beam of electrons is used to displace an electron from the organic molecule to form a radical cation known as the molecular ion. If the molecular ion is too unstable then it can fragment to give other smaller ions.

MS How It Works The collection of ions is then focused into a beam and accelerated into the magnetic field and deflected along circular paths according to the masses of the ions. By adjusting the magnetic field, the ions can be focused on the detector and recorded.

M.S. How It Works

M.S. Vocabulary Molecular ionThe ion obtained by the loss of an electron from the molecule Base peakThe most intense peak in the MS, assigned 100% intensity M+M+ Symbol often given to the molecular ion Radical cationPositively charged species with an odd number of electrons Fragment ions Lighter cations formed by the decomposition of the molecular ion. These often correspond to stable carbocations.

M.S. Spectrum 142 g/mol – 113 g/mol = 29 g/mol

M.S. Spectrum Why is there a small peak at 109 g/mol?

M.S. Spectrum Note presence of 79 Br and 81 Br

M.S. Spectrum

Acknowledgements I would like to acknowledge that most of the information presented came from the website: tudent/ol/ch13ms.html