DR. MOHAMMED ARIF. ASSOCIATE PROFESSOR. CONSULTANT VIROLOGIST. HEAD OF THE VIROLOGY UNIT. Medical virology, Laboratory session-1.

Slides:

Advertisements

Similar presentations

Complexities of Viral Nomenclature

Advertisements

Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.

Chapter 13-Viruses. General Characteristics of all viruses Contain a single type of nucleic acid Contain a protein coat Obligate intracellular parasites.

Introduction to Virology Lecture Outline u I. Objectives u II. Historical perspective u III. What is a virus –A. Characteristics –B. Comparison to bacteria.

Dr. Abdulkarim Alhetheel / Dr. Malak Elhazmi Assistant Professor College of Medicine & KKUH VIRAL GASTROENTERITIS.

General structure and classification of viruses

General properties of viruses 1-They are very small in size, from nm 2-They contain one kind of nucleic acid (RNA or DNA) as their genome 3-They.

VIRAL GASTROENTERITIS

Introduction to the Viruses: General properties of viruses: 1-They are very small in size, from  m. 2-They contain one kind of nucleic acid (RNA.

Single-stranded DNA, non-enveloped

Medically Important Viruses

VIRUS STRUCTURE AND CLASSIFICATION

Unit 3: Viruses!.

1 8/7/2015 Virus Structure & Classification developed by Hugh B. Fackrell.

DR.MOHAMMED ARIF ASSOCIATE PROFESSOR CONSULTANT VIROLOGIST HEAD OF THE VIROLOGY UNIT Cytomegalovirus (CMV)

Chapter 18.  1796 – Edward Jenner developed the smallpox vaccine  1897 – Beijerinck coined the term “virus” meaning poison  1935 – Wendell Stanley.

Chapter 14: Animal Viruses

Herpesviruses. 100 nm Herpesvirus structures are unique, with tegument layer present and genomic DNA wrapped around core.

Viruses Chapter 19 HIV virus Ebola virus H1N1 flu virus T4 bacteriophage Smallpox virus.

Chapter 13-Viruses. Viroids, and Prions

Introduction to Virology

What morphology is this virus?

1 What are Viruses? Obligate intracellular parasites Viral components –Nucleic acids –Capsid –Envelope.

Introduction to the Viruses: General properties of viruses: 1-They are very small in size, from  m. 2-They contain one kind of nucleic acid (RNA.

DR. MOHAMMED ARIF ASSOCIATE PROFESSOR CONSULTANT VIROLOGIST HEAD OF THE VIROLOGY UNIT Viral gastroenteritis ( Viral diarrhea ).

DR. MOHAMMED ARIF ASSOCIATE PROFESSOR CONSULTANT VIROLOGIST HEAD OF THE VIROLOGY UNIT Viral gastroenteritis ( Viral diarrhea ).

Prepared by :- Mohammed Osama El-Ifranji Classification of Medically Important Viruses.

Common viral infections HERPES VIRUS INFECTIONS The objectives of this lecture:  To know the clinically important HVs.  To know the common characteristics.

Classification of Medically Important Viruses Prepared by : Nour I. El-Haddad.

Virology 1 PM2 Pathophysiology.

In the name of Allah, Most Gracious, Most Merciful

Viral Infections: an overview Dr. Meg-angela Christi Amores.

Herpes viruses. Adenoviruses. Biological properties, pathogenecity for humans. Laboratory diagnostics, prophylaxis and therapy of diseases. Vinnitsa National.

DR.MOHAMMED ARIF ASSOCIATE PROFESSOR CONSULTANT VIROLOGIST HEAD OF THE VIROLOGY UNIT Epstein Barr virus (EBV)

Complexities of Viral Nomenclature No consistent system for naming viruses – some are named for the: associated diseases (e.g. poliovirus, rabies virus)

Classification of Classification is by two ways: 1. By structure of nucleic acid 2. By size, envelope, capsid shape Tobacco mosaic virus : 1.

Summary of virus introduction Two critical experiments that resulted in the discovery of virus –Infectious –Filterable agent Universal existence: Human,

Viruses: Edward Jenner first introduced term “virus” Dmitri Ivanosky in 1890 discovered virus for first time Virus is latin word derived from venom meaning.

General Properties of Viruses

CHAPTER 2: CLASSIFICATION OF VIRUSES

Chapter 13-Viruses of Bacteria. General Characteristics of all viruses Contain a single type of nucleic acid Contain a protein coat Obligate intracellular.

Viruses and what they do -

Chair of Medical Biology, Microbiology, Virology, and Immunology STRUCTURE, CLASSIFICATION AND PHYSIOLOGY OF VIRUSES.

Viruses DNA viruses: 6 families Poxviridae Herpesviridae Adenoviridae Hepadnaviridae Papovaviridae Parvoviridae.

Identification of virus Prepared by: Putri Shareen Binti Rosman.

Virus Classification And Description Mrs.Rekha.B Subject: Microbiology Class: B.Sc(N) 1 st year.

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Animal viruses/other infectious agents. Medgar Evers College Prof. Santos.

DR. MOHAMMED ARIF ASSOCIATE PROFESSOR CONSULTANT VIROLOGIST HEAD OF THE VIROLOGY UNIT General structure and classification of viruses.

Medical Virology  I. General Virology.  II. System Virology.  1- DNA viruses. 2- RNA viruses.

Superv. : Dr. Gomaa Abdelrahim Abdullalim By Khaled Al-Duraimeeh Abdullah Al-Sgair Majmaah University Collage of science in Al- Zulfi Medical.

VIRAL SHAPES. VIRUSES There are presently 20 recognized families of viruses that affect humans and/or animals CLASSIFIED BY: –By whether they contain.

VIRUSES. Helical VirusIcosahedral Virus Classification.

VIRUSES. What is a virus? “Virus” from the Latin “simply liquid, poison” Non-living organism Very very very small Most abundant Dependent on other living.

VIRAL STRUCTURE Image source: healthoma.com. Sources: raritanval.edu; slavirusportfolio.wikispaces.com, virology.wisc.edu.

Warm Up March 2 nd, )Viruses are non-_______. They also will attack and use other organisms to reproduce. What good could a virus do? 2)What is a.

Classification of Medically Important Two components of virus are used in classification : 1. Molecular weight & structure of nucleic acid 2.

Introduction to Viruses

Animal viruses/other infectious agents.

VIRAL GASTROENTERITIS

VIRUSES CHAPTER 10.

Classification of viruses

NOTES: CH 19 - The Genetics of Viruses

Prof Dr. Drh Pratiwi Ts,MS

Orthopedic & Muscular System: Current Research

VIRUSES CHAPTER 13 Gardasil® targets two strains of HPV that cause 70% of all cervical cancer, and two strains that cause 30% of genital warts.. Age 9-26.

INTRODUCTION TO MEDICAL VIROLOGY Asist.Prof.Baydaa Hameed

Presentation transcript:

DR. MOHAMMED ARIF. ASSOCIATE PROFESSOR. CONSULTANT VIROLOGIST. HEAD OF THE VIROLOGY UNIT. Medical virology, Laboratory session-1

Electron micrographs of medically important viruses  DNA - viruses : 1- Herpesviridae. 2- Adenoviridae. 3-Hepadnaviridae. 4- Poxviridae.

1- Family - Herpesviridae.  Enveloped, lose envelope.  Icosahedral nucleocapsid.  The viral genome is ds-DNA.  Eight human herpes viruses.  Examples of diseases:  HSV-1 : Gingivostomatitis, keratoconjunctivitis, meningoencephalitis, herpetic whitlow.  HSV-2 : Genital herpes, neonatal herpes.  varicella –zoster virus ( VZV ) : varicella, zoster.

Family – Herpesviridae.  Cytomegalovirus (CMV) : Infectious mononucleosis like syndrome, congenital infection, severe diseases in the immunocompromized.  Epstein Barr virus (EBV ) : infectious mononucleosis, Nasopharyngeal carcinoma, Burkitts lymphoma.

EM of herpes virus.

EM of herpes virus

2- Family- Adenoviridae  Unenveloped.  Icosahdral nucleocapsid ( spherical particle).  The viral genome is ds-DNA.  Examples of diseases : Pharyngoconjunctival fever, keratoconjunctivitis, pneumonia, gastroenteritis, hemorrhagic cystitis.

EM of adenoviruses

EM of adenoviruses.

3- Family : Hepadnaviridae ( hepatitis B virus ).  Three forms of particles.  The complete hepatitis B virus (HBV ) particle is enveloped with ds-DNA genome ( the large particles)  The free hepatitis B surface antigen particles (HBsAg), 22-nm in diameter.  The filament form of HBsAg particles.  Diseases : hepatitis B.

EM of Hepatitis B virus (HBV ).

4- Family : Poxviridae ( pox viruses ).  Brick shaped.  The viral genome is ds-DNA.  Complex structure.  Diseases : smallpox ( variola).

EM of poxvirus.

RNA viruses.  1- Family : orthomyxoviridae ( Influenza viruses ).  2- Family : Rhabdoviridae ( Rabies virus ).  3- Family : Reoviridae ( Rotaviruses).  4- Family : Caliciviridae ( Caliciviruses).  5- Family : Filoviridae ( Marburg virus & Ebola virus).  6- Arenaviridae ( Lassa virus ).

1- Family – Orthomyxoviridae ( influenza viruses ).  Pleomorphic.  Enveloped.  Covered with two glycoprotein spikes:  Hemagglutinin and neuraminidase.  The viral genome consists of 8- segments of ss-RNA.  Diseases : Influenza ( flue ), pneumonia.

EM of influenza viruses.

2- Family : Rhabdoviridae ( Rabies Virus ).  Bullet shaped.  Enveloped.  The viral genome is ss-RNA, negative strand.  Diseases : Rabies, acute encephalitis.

EM of Rabies virus.

3- Family : Reoviridae ( Rotaviruses).  Unenveloped.  The virus particle has a wheel structure (double capsid).  Spherical particles.  The viral genome consists of 11- segments of ds-RNA  Diseases : The major cause of infantile diarrhea.

EM of Rotaviruses.

4- Family : Caliciviridae ( caliciviruses ).  Unenvelpoed.  Spherical particles with cup- shaped depressions.  The viral genome is SS-RNA with positive polarity.  Diseases : Diarrhea.

EM of caliciviruses.

5- Family : Filoviridae. ( Marburg virus & Ebola virus).  The virus is filament in shape.  Unenveloped.  the viral genome is ss-RNA with negative polarity.  Diseases : Hemorrhagic fever.

EM of Marburg virus & Ebola virus.

Family : Arenaviridae Sandy appearance. Enveloped. ss-RNA, 2-segments with negative polarity. Lassa virus. Diseases : Lassa hemorrhagic fever.

Family Arenaviridae ( Lassa virus ).

family : Arenaviridae ( Lassa virus ).

Egg inoculation routes.  1- Chorio allantoic membrane ( CAM ).  2- Allantoic membrane.  3- Yolk sac.  4- Amniotic cavity.

Chorioallantoic membrane ( CAM ).

2-Allantoic cavity

3-Amniotic cavity

4-Yolk sac