Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane.

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Presentation transcript:

Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates by Gary Wong, Jason S. Richardson, Stéphane Pillet, Ami Patel, Xiangguo Qiu, Judie Alimonti, Jeff Hogan, Yi Zhang, Ayato Takada, Heinz Feldmann, and Gary P. Kobinger Sci Transl Med Volume 4(158):158ra ra146 October 31, 2012 Published by AAAS

Fig. 1 Survival and weight loss after challenge, and cellular and humoral immune response after vaccination in mice. Gary Wong et al., Sci Transl Med 2012;4:158ra146 Published by AAAS

Fig. 2 Survival and weight loss after challenge, humoral immune response after vaccination in guinea pigs. Gary Wong et al., Sci Transl Med 2012;4:158ra146 Published by AAAS

Fig. 3 Humoral immune response in cynomolgus macaques. Gary Wong et al., Sci Transl Med 2012;4:158ra146 Published by AAAS

Fig. 4 Cell-mediated immune response in cynomolgus macaques. Gary Wong et al., Sci Transl Med 2012;4:158ra146 Published by AAAS

Fig. 5 Cytokine and chemokine levels in cynomolgus macaques. Gary Wong et al., Sci Transl Med 2012;4:158ra146 Published by AAAS