LRTIs and Sepsis Poppy
Bronchitis/Pneumonia Bronchitis ▫Infection & inflammation of airways Pneumonia ▫Infection & inflammation of alveoli
Signs and Symptoms Signs ▫Fever ▫Tachypnoea ▫Crackles ▫ ↓ or bronchial breath sounds Symptoms ▫Dyspnoea ▫Cough ▫Sputum ▫Wheeze
Investigations PEFR Full blood count ( ↑ WCC) U&Es CRP Lactate ABGs CXR Nose & throat swabs (PCR tests) Sputum (microscopy, culture & sensitivities)
SEPSIS etc. SIRS ▫>1 of : Temp 38°C HR >90/min RR >20/min WCC 12x10 9 /dl SEPSIS ▫SIRS + known or suspected infection SEVERE SEPSIS ▫Sepsis + organ failure SEPTIC SHOCK ▫sepsis + hypotension (SBP <90mmHg) despite fluid resuscitation + perfusion abnormalities eg. lactic acidosis, ↓ UO, ↓ GCS
SEPSIS 6 1.Give high-flow oxygen 2.Take blood cultures 3.Give empirical IV antibiotics 4.Measure FBC & serum lactate 5.Start IV fluid resuscitation 6.Start accurate urine output measurements
CURB-65 Confusion Urea ▫>7mmol/L Respiratory rate ▫>30/minute Blood pressure ▫<90mmHg systolic or <60mmHg diastolic age ≥65 years old if score >1 → admit & if score >2 → IV treatment
Antibiotics CAP ▫Streptococcus pneumoniae ▫Staphylcoccus aureus ▫Haemophilus influenzae ▫Amoxicillin/Clarithromycin HAP ▫48-72h after being admitted ▫Often caused by multiple organisms Acute bronchitis ▫Often viral – no antibiotics!
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