Stem cell concepts renew cancer research by John E. Dick Blood Volume 112(13):4793-4807 December 15, 2008 ©2008 by American Society of Hematology.

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Stem cell concepts renew cancer research by John E. Dick Blood Volume 112(13): December 15, 2008 ©2008 by American Society of Hematology

John E. Dick. John E. Dick Blood 2008;112: ©2008 by American Society of Hematology

Labeling pattern of leukemic cells in marrow of patient 1. John E. Dick Blood 2008;112: ©2008 by American Society of Hematology

Models of tumor heterogeneity. John E. Dick Blood 2008;112: ©2008 by American Society of Hematology

Hierarchy of leukemia stem cells in AML. Like the normal hematopoietic system, AML is organized as a hierarchy of distinct cell classes that is sustained by a subset of leukemia stem cells (or SCID-leukemia initiating cells [SL-ICs], as assayed in immunodef... John E. Dick Blood 2008;112: ©2008 by American Society of Hematology

Models of tumor initiation and progression. John E. Dick Blood 2008;112: ©2008 by American Society of Hematology

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