TASHKENT MEDICAL ACADEMY

Slides:

Advertisements

Similar presentations

1 Classes of Lipids fatty acids triacylglycerols phospholipids Fat soluble vitamins steroids glycolipids *waxes * * fatty acids absent eicosanoids.

Advertisements

Lipids Introduction and classification

Biochemistry 2/e - Garrett & Grisham Copyright © 1999 by Harcourt Brace & Company Chapter 8 Lipids to accompany Biochemistry, 2/e by Reginald Garrett and.

Medical Biochemistry (2) Level 2 Part V (Lipids)

Lipids Biochemistry by Reginald Garrett and Charles Grisham

Introduction to Lipids. What are Lipids ?? Lipids are organic compounds which are related to fatty acids Lipids are insoluble in water & soluble in nonpolar.

Oils and fats. The definition of a lipid The definition of a lipid is based on solubility --- marginally soluble in water and soluble in organic solvents.

LIPIDS AND MEMBRANES. Fatty acids Hydrocarbon chain (saturated or un-) Carboxylic acid group C C HH HH.

LIPID CHEMISTRY. LIPID OF BIOLOGICAL IMPORTANCE Definition: Lipids are organic compounds, which have the following common properties: 1- They are esters.

Introduction  Lipids have a varied structure but all have the following properties in common:-  Insoluble in water  Soluble in organic solvents  The.

Lipids Function of Lipids

PROBLEMS CH 17. Learning Check Which lipids contain the alcohol glycerol? A. steroids and waxes B. triacylglycerols and glycerophospholipids C. sphingolipids.

Lipid Def: compounds which are relatively insoluble in water, but freely soluble in non polar organic solvents like benzene, ether, chloforom etc.

Medical chemistry (2) Part II (Lipids) week 4 lectures “Important reactions of lipids” Taif University College of Medicine Preparatory Year Students.

Structure of lipids Pavla Balínová. Lipids Lipids are a large and heterogenous group of substances of biological origin. They are easily dissolved in.

Lecture on the topic: Lipids, their structure and properties. For the 1st year students of specialty “General medicine". Discipline: Chemistry. Lecturer:

Lipids Qualitative. Lipids are the body’s principal energy reserve. About 85% of the deaths caused by cardiovascular disease are due to arteriosclerosis.

Presentation Lipids Michaela Barošová, Lukáš Malina.

CHEM 1152 Dr. Sheppard Spring 2015

Karaganda State Medical University. Chemistry department.

1 Chapter 15: Lipids Chem 20 El Camino College. 2 Lipids Lipids are a family of biomolecules that are not soluble in water but can be extracted by organic.

Molecular Cell Biology

What is Lipid Lipids: insoluble in water, but soluble in organic solvents including diethyl ether, chloroform, methylene chloride, and acetone Amphipathic:

Content fats and lipids structure and properties of phospholipids glycolipids steroids.

Lipid metabolism By Dr. Hoda Gad. OBJECTIVES BY THE END OF THESE LECTURES, STUDENT SHOULD BE ABLE TO:  Understand the structure of lipids including 

Lipids Monomers – fatty acids & glycerol Function- repel water, insulate, store the greatest amount of energy compared to other macromolecules Found in.

Medical Biochemistry (2) Level 2 Part II (Lipids) week 3 Taif University College of Medicine Preparatory Year Students.

LIPID CHEMISTRY.

Basic Biochemistry: Lipid Structure Dr. Kamal D. Mehta Department of Molecular & Cellular Biochemistry Wexner Medical Center at the Ohio State University.

Lipids: Fats & Oils.

6.3 Structure of Lipids Chapter 6 ~ The Chemistry of Life Section 6.3 p

Structure and function of cell components (i)Carbohydrates (ii)Lipids (iii)Proteins (iv)Nucleic Acids (v)Membranes (vi)Cytoskeleton.

Lipids General Characteristics Classification Biological function

Biomembranes: Structure and Biophysical Properties CHM 6304 section 5731 Spring 2006 meeting time MWF 8th (3-3:50) would like to move meeting to CLB 313.

Lipids. LIPIDS Lipids are a large and diverse group of naturally occurring organic compounds that are related by their solubility in nonpolar organic.

Lipids Triglycerides Phospholipids Sterols Lipids Lipids are a class of nutrients that includes: –Triglycerides (fats and oils) –Phospholipids –Sterols.

Chapter 17 Lipids 17.6 Sphingolipids.

LIPIDS The Molecules of Cells CH 3. Lipids Lipids include fats, which are mostly energy-storage molecules Lipids include fats, which are mostly energy-storage.

LIPIDS Biochemistry.

LIPIDS. A water insoluble compounds, but soluble in ether, benzena, acetone and chloroform Consists of glicerol & 3 fatty acids. Forms: solid lipid liquid.

LIPIDS Triglycerides, phospholipids and steroids.

Lipids. Mostly carbon and hydrogen Fats, oils, and waxes Can be used to store energy  Also, part of cell membrane, and waterproof coverings, steroids,

Pages 40 to 41.  Chemical composition  Carbon, hydrogen, oxygen and sometimes phosphorus  Building Blocks  Glycerol with 1 to 3 fatty acids  Phospholipids.

BIOCHEMISTRY Lipids. Lipids - fats and oils C, H, O (but lack the 2:1 ratio found in carbohydrates) Includes triglycerides, phospholipids and waxes Insoluble.

Lipids The term Lipid applies to a class of compounds that are soluble in organic solvent and nearly in soluble in water. Chemically:

Goals of the Day… Lipids… Types of fatty acid lipids

DefinitionClassification Biological importance Organic substances relatively insoluble in water but soluble in organic solvents like chloroform, ether.

1 Chapter 15 Lipids 15.1 Lipids Copyright © 2007 by Pearson Education, Inc. Publishing as Benjamin Cummings.

lipids fixed oils and waxes

What is Lipid Lipids: Lipids: insoluble in water, but soluble in organic solvents including diethyl ether, chloroform, methylene chloride, and acetone.

Lipids. Lipids are non-polar (hydrophobic) compounds, soluble in organic solvents. 1. Simple lipids: esters of FA with alcohols Fats: alcohol = glycerol.

 Also known as fats  Made of carbon, hydrogen, and oxygen  When your body breaks down lipids, it turns it into fatty acids and glycerol.

Chapter 13 Lipids Sections

LIPIDS What Is a Lipid? A lipid is a fat-soluble molecule. To put it another way, lipids are insoluble in water but soluble in at least one organic solvent.

Sample Problem 17.1 Structures and Properties of Fatty Acids

Chemistry 121 Winter 17 Introduction to Organic Chemistry and Biochemistry Instructor Dr. Upali Siriwardane (Ph.D. Ohio State)

LIPIDS Biochemistry.

Lipids Why this Chapter?

Lipids of Physiological Significance

Midterm -as per course syllabus

Lipids Dr. Tarek Zaida.

Bioorganic Lipids 4/6/2019 Dr Seemal Jelani Chem-160.

Department Of Quality Assurance K.Y.D.S.C.T’s College of pharmacy

Bioorganic Lipids 12/5/2019 Dr Seemal Jelani Chem-160.

Presentation transcript:

TASHKENT MEDICAL ACADEMY Department of Bioorganic and Biological Chemistry Bioorganic chemistry I COURSE SUBJECT : Lipids. Saponifiable lipids LECTURE №14 LECTURER : PROFESSOR A.D.DZHURAEV

PURPOSE OF LECTURES: Form of knowledge of the structure and chemical properties of saponifiable lipids and their structural components such as the chemical basis for the study of biological membranes and processes of lipid metabolism.

The questions of: Lipids. Determination of saponifiable lipids. Simple lipids. Fats, oils and waxes. The types and properties of fatty acids comprising the saponifiable lipids. Complex lipids. The structure of phospholipids, sphingolipids, and glycolipids. Saponifiable lipids and properties of its structural components.

Determination of lipids Lipids - a group of substances found in the tissues of plants and animals, not very soluble in water and soluble in low-polarity solvents. The functions of lipids - 1. energy Sources 2. protective 3.stroitelny material of cell membranes

Classification saponifiable lipids

Saturated acid: C14 CН3(CН2)12COOН, C13 Н27COOН - myristic C16 CН3(CН2)14COOН, C15 Н31COOН - palmitic C18 CН3(CН2)16COOН, C17 Н 35COOН - stearic C20 CН3(CН2)18COOН, C19 Н39COOН - arachidonic

Unsaturated acids C18:1 C17Н33COOН - oleic C18:2 C17Н31COOН - linoleic C18:3 C17Н29COOН - linolenic C18:4 C1 9Н31COOН - arachidonic

Pro – Stain Acid

Palmitic acid C H 3 O + 7 2 2[H] 15 31 14 Palmitic acid

Simple lipids Waxes Remainder of cetyl alcohol Остаток мирицилового спирта

Fats and oils Triolein - oleo-- palmityl-1- stearin

Glycerophospholipids Complex lipids phospholipids Glycerophospholipids Glycerophosphate dehydrogenase L-glycero-3-phosphate dihydrogen acetone

Sphingolipids ceramide sphingosine sphingomyelin

Glycolipids ceramide residue galaktotserebrozid

Composition and properties of saponifiable lipids Tsetilpalmitat palmitic acid cetyl alcohol 1-2-palmito oleostearin soap phosphatidyl kolamin (Kefalonia)

The addition reaction: Tristearin (salomas) Triolein

Oxidation reaction hydroperoxide break

Oxidation of unsaturated acids peroxy acid oleic acid 9,10-эпоксистеариновая кислота

Oxidation of oleic acid pelargonic acid oleic acid azelaic acid