2 John is a 57 year old man who developed gait difficulty which has worsened over the past months. He noticed that he needed to stand for apart to maintain.

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2 John is a 57 year old man who developed gait difficulty which has worsened over the past months. He noticed that he needed to stand for apart to maintain his balance and that he waddled when he walked. When tested by the neurologist, there was no sensory loss nor speech deficits. When asked to touch the doctor’s fingers then his nose, John missed his nose slightly. When asked to slide his right heel down his left shin, his heel slid sideways and clumsily across. The doctor ordered an MRI of Johns’s head.

1. What term could be used for John’s gait a. Stiff b. Fesinating c. Ataxia d. Spastic 2. Where is the lesion a. Posterior columns only b. Cerebellar tracts only c. Cerebellum d. Spinothalamic tract

3. Where in the brain would the neurologist expect to visualize it on MRI? a. Red nucleus b. Cerebellar vermis c. Cerebellar cortex d. Internal capsule

Case 1 Mr X, a 66-year-old gentleman, presented to the emergency department with progressively worsening unsteadiness on his feet, double vision, nausea and vomiting. Two months previously the patient noticed he was becoming unsteady on his feet. This progressed such that he was now struggling to walk unaided. Four days prior to his admission the patient developed persistent nausea and vomiting and noticed double vision. It was this that brought him to the emergency department. The patient denied any headaches, vertigo, weakness, confusion, bowel or bladder dysfunction and the unsteadiness was independent of position. Bowel movements were normal and he reported no other symptoms of abdominal pathology. The patient drank on average 10 units of alcohol a week and reported no recent increase in consumption.

His blood pressure was 120/94mmHg, pulse rate 107bpm, respiratory rate 14 and temperature 37.4C. He was able to sit upright in the bed unsupported. Of note there was no clubbing of the fingernails, no signs of malnutrition and no slurring of speech. In depth neurological examination revealed a wide-based gait with inability to walk in tandem gait. Tone and power were normal; intention tremor with past pointing was present bilaterally. The patient reported diplopia at all eye positions with images displaced horizontally, there was no noticeable nystagmus.