Mad Cow Disease Making sense of the headlines by Trevor Murdock.

Slides:

Advertisements

Similar presentations

Creutzfeldt-Jakob Disease Classic CJD occurs worldwide at 1-2 cases per million population per year In people over 50, the annual rate is about 3.4 per.

Advertisements

Current Issues in Food BSE Claire Appleton and Carrie Thompson (NHS)

Bovine Spongiform Encephalopathy (BSE) in Canada Pedro Piccardo, MD Division of Emerging and Transfusion-Transmitted Diseases Office of Blood Research.

Food Safety Mad Cow Disease Unit 5 HW A. This week’s seminar –History of Mad Cow Disease (MCD) –What causes MCD and its effect? –How does HACCP.

Prions Sly Richards.

Draft Guidance for Industry: Preventive Measures to Reduce the Possible Risk of Transmission of Creutzfeldt-Jakob Disease (CJD) and Variant Creutzfeldt-Jakob.

1 Donor Deferral / Ineligibility for Time Spent in Saudi Arabia to Reduce Risk of vCJD Transmitted by Blood and Blood Products and by Human Cells, Tissues.

Predicting an Epidemic A Quantitative Assessment of TSE Sampling Data to Predict Outbreak Magnitude Aspen Shackleford HONR299J.

Analysis to Inform Decisions: Evaluating BSE Joshua Cohen and George Gray Harvard Center for Risk Analysis Harvard School of Public Health.

Mad Cow Disease 袁聖甯黃竹瑄鄧雯心. What is Mad Cow Disease ? A kind of transmissible spongiform encephalopathies (TSE) Occurs in many mammals, including human.

Do Now: Complete the chart on your notes as completely as possible.

BSE outbreaks in the United States and Canada and the Impact on Trade Hyun J. Jin Won W. Koo Center for Agricultural Policy and Trade Studies North Dakota.

PRIONS Defn: small proteinaceous infectious particles that resist inactivation by procedures that modify viruses and nucleic acids.

Are humans susceptible?

1 Transmissible Spongiform Encephalopathies. 2 Kuru Since the early 1900’s the Fore people of New Guinea have honored their dead by cooking and consuming.

Bovine Spongiform Encephalopathy Luke VanNatter Carrie Pell Amy Richwine Scott Inskeep Kristina Anderson.

Prions Fact or Science Fiction?. Stanley Prusiner, 1982 Born in Des Moines, Ia. Suggested that spongiform encephalopathies in animals and humans are caused.

Prions Alicia Arguelles, Jerry Wang May 4, What are prions? proteinaceous infectious particle an infectious agent made only of protein, containing.

Mad Cow Disease. Effects of Mad Cow disease Mad cow disease, or bovine spongiform encephalopathy (BSE), is a fatal brain disorder that occurs in cattle.

Lesson 2: How Does Your Garden Grow? Meat and Milk Production.

Harvard Center for Risk Analysis Evaluation of the Potential for BSE in the United States Joshua T. Cohen Keith Duggar George M. Gray Silvia Kreindel Harvard.

Canadian and U.S. BSE Risk Steven Anderson, Ph.D, MPP Office of Biostatistics & Epidemiology Center for Biologics Evaluation & Research U.S. Food & Drug.

Prion Diseases Microbes and Society Fall What is a Prion? Prion- small proteinaceous infectious particles which resist inactivation by procedures.

Evolution of the Mad Cow Disease in the United States Denish Moorthy, Eugene Shubnikov, Ron LaPorte The Supercourse Network of the Global Health University.

BOVINE SPONGIFORM ENCEPHALOPATHY (BSE) or “Mad Cow Disease”: Cause and effect on the beef market. Name: Odette K Busambwa.

To-Vi Nguyen.  Vicky Rimmer- 15 yr old girl  Was in a coma within half a year  “Human Mad Cow Disease”- CJD unheard of in someone so young  1993-

 Caused by parasite › Transmitted by mosquito › Once injected into the human, the parasite grows and multiples first in the liver and then the red blood.

Transmissible Spongiform Encephalopathies Ryan Maddox, MPH Creutzfeldt-Jakob Disease Surveillance Unit Division of Viral and Rickettsial Diseases National.

ALZHEIMER’S PART 2. AD VIDEO

The Pathological Protein, Chapters 8-9 Rhiannon Aguilar HONR299J March 27, 2014.

Transmissible Spongiform Encephalopathies (TSEs) a.k.a. Prion Diseases Transmissible  can be spread Spongiform  resembling a sponge Encephalopathies.

Bovine-derived Products Used in the Manufacture and Formulation of Vaccines and Allergenic Products: Minimizing TSE Risks William M. Egan, Ph.D. Acting.

Mad Cow Disease Nathan Blessum Advanced Animal Science Instructor: Randall A. Cale

By Shon Augustine. Mad cow disease is an incurable, fatal brain disease that affects cattle and possibly some other animals, such as goats and sheep.

Prions: Proteins Gone Bad

Variant Creutzfeldt-Jakob Disease (vCJD). By Georgie Hill 10 Science 2 CJD Bacteria.

By : Amirah nu’aimi Sharifah Nurul Hanim TASK 2 – DISCUSS THE EXAMPLE OF PROTEIN FOLDING DISEASE BY STATING THE MECHANISM.

PRIONS Kalina Estrada TA: Yu-Chen Hwang Thursday, 7-8pm.

Risk Assessments: Models for Estimating the Risk of Transmitting TSE by Human Tissue Intended for Transplantation Rolf E. Taffs, Ph.D. Center for Biologics.

EEE 105 Name: eee105 Password: prAIRie Agriculture.

January 2002 WHO/CSR/APH Efforts and needs for global control of BSE and vCJD Maura N. Ricketts MD MHSc FRCPC WHO/CDS/CSR/EPH.

Mad Cow Disease Caitlin Brandt 3&tbm=isch&tbnid=SBeGwN- sN8InuM:&imgrefurl=

 Foreign Sources of Infection To − Vi Nguyen. Foreign Infection  Preventable environmental source of infection  Remove infectious material, epidemic.

Trade & Economic Impacts of Animal Disease Outbreaks Parr Rosson Professor & Director Center for North American Studies Texas A&M University.

UEVP is a section of the Federation of Veterinarians of Europe Union européenne Des vétérinaires praticiens EURALIA BRIEFING.

 slowly progressive, degenerative, and fatal disease affecting the central nervous system of adult cattle.  abnormal version of a protein normally found.

RISK COMMUNICATION APPROACH TSEAC 15 December 2006 Mark Weinstein, Ph.D. FDA, Center for Biologics Evaluation and Research.

Kuru A PRION DISEASE.

Microbes and Diseases Chapter 02. CREUTZFELDT-JAKOB DISEASE Prion.

Studying Biology: Start with a question. –For example: How? Why? When? Where? Etc? How do we get answers? –Strong Inference presents one method (article.

Topic 1: FDA Draft Guidance “Revised Preventive Measures to Reduce the Possible Risk of Transmission of CJD and vCJD by Blood and Blood Products” Dorothy.

David M. Asher, MD Division of Emerging & Transfusion-Transmitted Diseases Office of Blood Research & Review Center for Biologics Evaluation & Research.

1 A Simulation Model to Quantify the Spread of BSE in the United States Joshua Cohen and George Gray Harvard Center for Risk Analysis Harvard School of.

Mad Cow Disease By: Rylee and Cassidy. What is it? Mad Cow disease is a incurable, fatal brain disease that affects cattle and sometimes goats and sheep.

FDA Risk Management Strategy for Potential Exposure to vCJD from Plasma Derivatives TSE Advisory Committee December 15, 2006 Dorothy Scott, M.D. OBRR/CBER.

Mad cow disease The 2001 biology project Made by TommyChan.

Creutzfeldt-Jakob Disease Atif Chohan & Alex Brown.

INTEGRATED CONTROLS DIVISION Cross Compliance Farm Advisory Service Training 2016 SMR 5 ‘ Hormone Ban’

Species identification

VIRUSES and THEIR RELATIVES VIRUSES and THEIR RELATIVES.

By: Terry Bender and Dustin Rozier Students of Dr. James Corbett Lowndes County High School Valdosta, Georgia November, 2002.

VIRUSES and THEIR RELATIVES

(Bovine spongiform encephalopathy)

MICROBIAL FOOD SAFETY A FOOD SYSTEMS APPROACH

Bovine Spongiform Encephalopathy Variant Creutzfeldt-Jakob disease

Chapter 22: Diseases of the nervous system

Brain Trust Chapt 22: Origins

Frequently Asked Questions About BSE

By Alagu Paramesh Veerappan And Grant Ellison

Presentation transcript:

Mad Cow Disease Making sense of the headlines by Trevor Murdock

Outline n What is Mad Cow Disease? n What is CJD? n What has happened so far? n North America - Status n North America - Signs of Mad Cow Disease?

What is Mad Cow Disease? n Transmissible Spongiform Encephalophy (TSE) –Scrapie - Sheep –BSE - Cows –Kuru - Cannibals

What is CJD? n CJD - Humans –brain-wasting disorder: blindness, dementia, loss of motor functions –natural occurrence 1 in a million –average age 63 n vCJD - Humans, transmissible –from beef (or other meat/animal products)? –onset at earlier age –incubation depends on exposure

What has happened so far? n Britain n Europe n Government (in)action –protect cattle industry (at expense of citizens! & history repeated with FMD) n Media attention –also focus on cattle industry more than people

North America - Status n ruminants still eating parts of ruminants (scrapie infected sheep are fed to pigs) n 13 percent of 397 US feed mills that process meat and bone meal have no system for preventing products from being mixed!!! n spray-dried blood products in feed n gelatin?, dairy?, bovine-derived products, including glandular extracts, collagen, glucosamine and chondroitin n virtually no testing !!! - Italy only found BSE when it started testing

North America - Signs of Mad Cow Disease? n Apr Nov 1997, NE Texas (~1 million): 8 CJD cases (younger than average). From the Texas Dept of health as quoted by Howard Lyman in Mad Cowboy. n Pittsburgh autopsies of 54 patients died of dementia, 3 of them had CJD. From Neurology, 1989, 39 (1): pp as quoted by Howard Lyman in Mad Cowboy. n Alzheimer’s ??? - similar symptoms

Canada n cattle fed to cattle in Canada until good chance of BSE +ve offspring in food chain NOW n 11 cattle from Britain got into Canada’s food chain in 1993 (according to a European Union scientific committee) n 2 blood donors had died of CJD in 1995 n Canada not in lowest risk rank ( European Commission report 2000)

Summary n Mad Cow Disease risk is real n Cannot wait for government to protect the food supply (deny human risk as long as possible, protect industry) n Many questionable practices remain n Increased exposure --> increased risk and reduced incubation period n Best protection: reduce --> eliminate beef, meat, dairy, gelatin, etc.