The Incidence and Influencing factors of functional disability in Chinese Patients with Rheumatoid Arthritis West China School Of Nursing, West China Hospital,

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The Incidence and Influencing factors of functional disability in Chinese Patients with Rheumatoid Arthritis West China School Of Nursing, West China Hospital, Sichuan University, China Shangping Zhao , Yanling Chen, Hong Chen 1

Contents  Background  Purpose  Methods  Results  Conclusions 2

Background Rheumatoid Arthritis: RA  A chronic, autoimmune and Invasive arthritis  Immortal tumor:  Disability , Discomfort , Dollar cost , Drug toxicity , Death 3

 0.42%, Cross M. Smith E. Hoy D. et al. Annals of the Rheumatic Diseases. 2014,73(7): Zeng XF. et al. Chinese Journal of Evidence-based.2013,13 (3):

Background 5

functional disability--feet 6

functional disability--hands 7

Purpose  Investigate the incidence of functional disability in Chinese patients with RA  Analyze influencing factors of functional disability in Chinese patients with RA  Provide reference for intervention on functional disability of RA 8

Methods  A cross-sectional survey  Convenience sampling in Rheumatic Outpatient in West China Hospital  September to December 2013  Demographic data , social support , pain , fatigue , functional disability 9

measurements -1  Demographic data  age  gender  marital status  education level  residence  family monthly income per capita (FMIPC)  medical payment forms  disease duration  hospitalized times  total cost of treatment (TCT)

measurements -2  Social support  Social Support Rating Scale , Higher scores indicate more social support  Pain, fatigue  Visual Analog Scale  Functional disability  Health Assessment Questionnaire-Disability Index (HAQ-DI) , Higher score of HAQ-DI indicates more damage of physical function

Results-1 Statistical description  607 of 653 participants 12

Statistical description 13

Statistical description 14

Statistical description VariablesMean±SD or MedianRange Age (years)5018, 88 Disease duration ( month ) 501, 492 VAS of Pain5.25 ± 2.910, 10 VAS of Fatigue4.15 ± 2.870, 10 Social support rating scale40.67 ± , 58 15

Statistical description 16 MeanSD HAQ-DI dressing and grooming arising eating walking hygiene reaching gripping other activities

Statistical description  58.5% of patients had functional disability. 17

Results-2 VariableHAQ-DIP Gendert= Marital status F= Education level F=15.682<0.001 Residence F=12.647<0.001 FMIPC (Yuan) F=10.364<0.001 Medical payment forms F= FMIPC:family monthly income per capita 18 Univariate analysis

19 HAQ-DI Education levelPrimary school or below 0.86 ± 0.68F=15.682<0.001** Junior high school 0.66 ± 0.68 Senior high school 0.51 ± 0.63 College or above 0.30 ± 0.44 ResidenceUrban 0.49 ± 0.64F=12.647<0.001** Suburban 0.71 ± 0.70 Rural 0.79 ± 0.67 family monthly income per capita (Yuan) < ± 0.64F=10.364<0.001** ± ± 0.74 > ± 0.49

Table 3 Multivariate regression of functional disability of patients with rheumatoid arthritis ( N=607, Adjusted R2=0.384 ) Included variablesBP95% Confidence internal (95%CI) Suburban *0.002,0.248 Rural *0.045,0263 Age0.012<0.001**0.009, Disease duration *0.000, Hospitalized times *0.011, Overall cost for treatment0.002<0.001**0.001, Pain0.094<0.001**0.079, Subjective social support-0.019<0.001**-0.028, Available social support *-0.044,

Results- Multivariate regression  Adjusted R 2 =0.384  Pain, age, disease duration, total cost for treatment and hospitalized times was negative factors  Subjective and available social support was positive factors 21

Conclusion  Functional disability is a common symptom in our study.  When providing patient education, nurses should consider more about patients with RA who live in rural residence, have a low level of income and education and long disease duration.  Pain management with a sound social support system is a possible good intervention 22

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