Www.aids2014.org Does HIV serosorting increase syphilis prevalence among men who have sex with men in Western Europe? - A mathematical modelling study.

Slides:

Advertisements

Similar presentations

Kessler, J. Myers, J.E. ; Nucifora, K.A. ; Mensah, N. ; Kowalski, A. ; Sweeney, M. ; Toohey, C. ; Shepard, C. ; Cutler, B. ; Braithwaite, R.S. Modeling.

Advertisements

National Institute for Public Health and the Environment HIV, HCV, and HBV in injecting drug users in Europe Mirjam Kretzschmar Centre for Infectious Disease.

Sexually Transmitted Diseases Among Men Who Have Sex with Men: A need for new prevention and research strategies National Sexually Transmitted Disease.

STIGMA AND DISCRIMINATION REDUCTION AS AN ESSENTIAL PART OF COMBINATION PREVENTION Stefan Baral, MD MPH FRCPC Center for Public Health and Human Rights,

Increased routine screening for syphilis and falling syphilis incidence in HIV positive and HIV negative men who have sex with men: implications for syphilis.

STD Screening in HIV Clinics: Value and Implications Thomas Farley, MD MPH Tulane University Deborah Cohen, MD MPH RAND Corporation.

Syphilis Trends in the United States James D. Heffelfinger, MD, MPH Epidemiology and Surveillance Branch, DSTD Centers for Disease Control and Prevention.

Treatment as prevention: cannot succeed without increased testing AND PRIMARY PREVENTION example from the United Kingdom? Dr Valerie Delpech Head of HIV.

Trading sex and building Capital: Sexual Identity and the Programmatic Challenges of reaching young African MSM S. Leclerc-Madlala 1,

National Institute for Public Health and the Environment Comparison of network models for STI transmission and intervention: how useful are they for public.

HIV in the United Kingdom: 2013 HIV and AIDS Reporting Section Centre for Infectious Disease Surveillance and Control (CIDSC) Public Health England London,

Office of Global Health and HIV (OGHH) Office of Overseas Programming & Training Support (OPATS) HIV Prevention Training Package Session 1: Introduction.

Attaining Realistic and Substantial Reductions in HIV Incidence: Model Projections of Combining Microbicide and Male Circumcision interventions in Rural.

HIV Modelling & Economics Estimating the potential impact and efficiency of PrEP for FSWs and MSM in Bangalore, southern India K.M. Mitchell 1, H.J. Prudden.

1 Lauren E. Finn, 2 Seth Sheffler-Collins, MPH, 2 Marcelo Fernandez-Viña, MPH, 2 Claire Newbern, PhD, 1 Dr. Alison Evans, ScD., 1 Drexel University School.

Predictors of HIV Transmission Risk among Patients in Care: Results from the SPNS Prevention with Positives Initiative Stephen F. Morin, PhD Principal.

Sex work among people who inject drugs in England, Wales & Northern Ireland: Findings from a National Survey of Health Harms and Behaviours Sara Croxford,

1 Syphilis Among Men Who Have Sex with Men: Limitations of Traditional Case and Partner Services, San Diego, CA, Robert A.Gunn, MD, MPH Azi.

Syphilis Sexually Transmitted Disease Surveillance 2008 Division of STD Prevention.

Syphilis Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention.

Patients in routine HIV clinical care at-risk for potentially transmitting HIV in the “test and treat” era of HIV prevention Crane, HM, Mimiaga, M, Feldman,

Nuanced seroadaptive behaviors among Seattle MSM: sexual decision- making based on ART use/viral load and recency of partner HIV testing Christine M. Khosropour,

Background Donor Suitability Consultation was held in Atlanta June 26-27, 2001 To review and consult on the 1994 CDC Guidelines for Preventing Transmission.

Monitoring the effects of ARV treatment programmes on prevention Gabriel Mwaluko 1, Mark Urassa,2, John Changalucha,2, Ties Boerma 3 1 TANESA Project,

Overview of the State of the HIV Epidemic in Canada Regional Session on USA and Canada XIX International AIDS Conference Howard Njoo MD, MHSc, FRCPC Director-General.

DATA, DATA, DATA: What to Make of It And How To Use It Florida Consortium for HIV/AIDS Research The AIDS Institute DRAFT.

Ratios,Proportions and Rates MAE Course Measures of frequency The basic tools to describe quantitatively the causes and patterns of disease, or.

N ORTHWEST AIDS E DUCATION AND T RAINING C ENTER PrEP 201: Beyond the Basics Joanne Stekler, MD MPH Associate Professor of Medicine University of Washington.

Racial Disparities in Antiretroviral Therapy Use and Viral Suppression among Sexually Active HIV-infected Men who have Sex with Men— United States, Medical.

Context and Association of Meth Use and Sexual Risk Behavior David W. Purcell, JD, PhD Prevention Research Branch Division of HIV/AIDS Prevention, NCHHSTP,

Sexually Transmitted Infections Mysheika Williams Roberts, MD, MPH Medical Director Assistant Health Commissioner Columbus.

Public Health in Tropics :Further understanding in infectious disease epidemiology Taro Yamamoto Department of International Health Institute of Tropical.

HIV Prevention and Treatment for Men who have sex with Men: Achievements and Challenges Ifeanyi Kelly Orazulike National Coordinator Sexual Minorities.

HIV/STD Research Program Thailand MOPH – US CDC Collaboration Bangkok, Thailand IAS 2015 July 21, 2015: TUAC0302 HIV/STD Research Program Division of HIV/AIDS.

HIV Prevention in Kenya: Lessons Learned from the 2007 Kenya AIDS Indicator Survey Carol Ngare KAIS TWG Member, NASCOP-MOH Prevention Summit 2008 HIV Prevention.

HIV and STI Department, Health Protection Agency - Colindale HIV and AIDS Reporting System HIV in the United Kingdom: 2012 Overview.

Quarterly HIV/AIDS Analysis for Michigan January 1, 2008 Michigan Department of Community Health HIV/STD/Viral Hepatitis and TB Epidemiology Section Division.

Return on investment: How do whole societies benefit from improved services and coverage for key populations? Bradley Mathers Kirby Institute UNSW Australia.

Threshold, Amory Faulkner, oil on canvas 1 The prospects of elimination of HIV with test and treat strategy Mirjam Kretzschmar 1,2 Maarten Schim van der.

Historical Mapping of HIV Programmes 1985 – 2012 in Malawi Presented at the 20 TH INTERNATIONAL AIDS CONFERENCE, MELBOURNE, AUSTRALIA 24 th July 2014 By.

Advancing Nursing Leadership Factors Predicting HIV-related Knowledge Among Urban Health Workers In Malawi Sri Yona, 1 So Hyun Park, 1 Jane L. Chimango,,2.

HIM HEALTH A Social Franchise for Key Affected Populations in low to middle income countries.

Trends in HIV diagnoses in Ontario, 20002004 Robert S. Remis, Jane Njihia, Carol Swantee, Maraki Fikre Merid Ontario HIV Epidemiologic Monitoring Unit,

 MSM, specifically HIV-positive MSM, have a high risk of anal cancer caused by human papillomavirus (HPV).  It has been suggested that MSM attending.

Decline in incidence of HIV and Hepatitis C virus infection among injecting drug users in Amsterdam; evidence for harm reduction? 1. Julius Center, University.

HIV and STI Department, Health Protection Agency - Colindale HIV and AIDS Reporting System The threshold for an ART secondary prevention effect on HIV.

Sexually Transmitted Infections in Europe, 2012 European Centre for Disease Prevention and Control.

Assessing policy impact on HIV intervention targeting MSM in Abuja, Nigeria Ifeanyi kelly Orazulike.

Behavioral Research and STIs Objectives l Discuss how behavior influences the basic reproductive rate of an epidemic l Describe some of the behavioral.

1990–2010 Sexually Transmitted Infections in Europe European Centre for Disease Prevention and Control.

Ecdc.europa.eu Epidemiological Situation of HIV/AIDS in the EU and its Neighbouring Countries German Presidency Conference Responsibility & Partnership.

Allie Lyman.  Incidence and Prevalence  Risk Factors and Barriers to Prevention  Prevention  Conclusion.

Criminalization of same-sex behavior is harmful to public health: Significant reductions in access to HIV prevention and care services associated with.

Advisory Forum November 28th-29th 2005 HIV, AIDS and Other Sexually Transmitted and Blood Borne Infections Prof Angus Nicoll SNE - HIV & STI Co-ordinator.

Inequalities in Sexual Health. Update on HIV and STIs in men who have sex with men in London Field Epidemiology Services PHE Publications gateway number:

Sexually transmitted disease diagnoses associated with exchange sex among male Hispanic migrants who have sex with men in the United States Abstract TUPDC0106.

Contributions of Behavioral Research to HIV/AIDS Studies and to Health Promotion EDCTP workshop, Prague 23.October 2009.

Zindoga Mukandavire Social and Mathematical Epidemiology Group London School of Hygiene and Tropical Medicine, UK Improving health worldwide

Bad Blood? An Investigation of the MSM Ban on Blood Donation Lauren Lacy Abstract In 1983, the Food and Drug Administration (FDA), responding to the AIDS.

Evidence of international transmission of HCV in pan-European study of HIV- positive men who have sex with men (MSM). M Danta 1,9 *, T van de Laar 4 *,

Correlates of HIV testing among youth in three high prevalence Caribbean Countries Beverly E. Andrews, Doctoral Candidate University.

Global Impact of HIV/AIDS Deborah Lewinsohn, M.D. Infectious Diseases, Pediatrics Vaccine and Gene Therapy Institute Oregon Health & Science University.

Demographic and Behavioral Differences between Latino and non-Latino Patients Attending Baltimore City STD Clinics, Renee M. Gindi 1, Kathleen.

Imperial College London

Htat HW1, Longfield K1, Mundy G1, Win Z1, Montagu D2.

International Union against Sexually Transmitted Infections

John de Wit1,2, Dean Murphy2,3, Luxi Lal4,5,6, Jennifer Audsley5,7, Christopher K. Fairley8,9, Mark Stoove4,10, Norm Roth11, Richard Moore12, Ban K.

HIV infections newly diagnosed in injecting drug users and men who have sex with men, by country, and year of report, 2002– Injecting drug users.

Kyle T. Bernstein, Katherine Ahrens, Susan S. Philip, Jeffrey D

Division of STD Prevention Centers for Disease Control and Prevention

Presentation transcript:

Does HIV serosorting increase syphilis prevalence among men who have sex with men in Western Europe? - A mathematical modelling study - A. Lucht 1, M. Shah 2, M. Kretzschmar 3,4 1 Labor Krone, Siemensstraße 40, D Bad Salzuflen, Germany 2 Johns Hopkins University, Division of Infectious Diseases, Baltimore, MD, US 3 University Medical Centre Utrecht, Julius Centre for Health Sciences & Primary Care, Utrecht, Netherlands, 4 Centre for Infectious Diseases Control, RIVM, Bilthoven, Netherlands Abstract no. TUPDC0106

Background Serosorting definition: –“restriction of sexual partnerships to those perceived to be of the same HIV serostatus”. Serosorting is sometimes used as an HIV risk reduction strategy among men who have sex with men (MSM). Some studies suggest serosorting may reduce HIV transmission However, serosorting may increase transmission of other STIs such as syphilis Syphilis prevalence is high and increasing among MSM in several Western European countries

Study Aims and Methods Primary Study Aim: –To assess the impact of serosorting on syphilis prevalence among MSM in Western Europe (UK, Netherlands, and Germany) using a deterministic S-I-R-S mathematical model Secondary outcomes: –To examine the impact of HIV prevalence and sexual risk behaviors on the impact of the serosorting effect Differential Equations describing rates of each compartment Legend: S-susceptible, I = infectious, R = resistant.

Results and Conclusions CONCLUSIONS HIV serosorting increases syphilis prevalence among MSM compared to scenarios without serosorting –Effect is more pronounced in HIV-positive compared to HIV-negative –Even small proportions of serosorting among MSM leads to increases in syphilis prevalence The size of the serosorting effect on syphilis prevalence is increased by: –higher HIV prevalence in the MSM population, –higher numbers of sexual partnerships of HIV-positive and HIV-negative MSM, –Increased probability of syphilis transmission per partnership (e.g. without condom usage) RESULTS: Effect of serosorting on syphilis prevalence among HIV-positive MSM Base-Case syphilis prevalence: Base-case Serosorting 4-12% HIV % HIV+ HIV+: % HIV-: % (range is across UK, Germany, Netherlands)