Aim: How does our immune system protect against antigens of pathogenic organisms? HW 22 Read Ch 40 pages 1028 – 1048 Pg 1034 vocabulary Pg 1050 Thinking visually copy and complete concept map.

The human immune system is made up of… Lymphatic vessels lymph nodes lymphoid tissue –bone marrow, thymus, tonsils, adenoids, Peyer's patches, and the appendix

and cells…

Cellular barriers to infection Neutrophils – Polymorphonuclear cells are recruited to the site of infection where they phagocytose invading organisms and kill them intracellularly

Cellular barriers to infection Macrophages – Tissue macrophages function in phagocytosis and intracellular killing of microorganisms.

Cellular barriers to infection Eosinophils have proteins in granules that are effective in killing certain parasites

How do Lymphocytes Produce Antibodies? Antibodies are.. Molecules in the blood or secretory fluids that tag, destroy, or neutralize bacteria, viruses, or other harmful toxins Antibodies are chemicals that have antigen binding sites Antigens are proteins on the foreign body (pathogens). AntibodyAntigen Antigen- binding sites

Bacteria With Antigens on Surface Macrophage T cell B cell Active B cells T cell Section 40-2 Humoral immunity is the body’s immune response Plasma cell

Bacteria With Antigens on Surface Macrophage T cell B cell phagocyte called a macrophage engulfs a bacterium Active B cells proliferate to produce clones of memory cells T cell, activated by macrophage, becomes a helper T cell Antigens are displayed on surface of macrophage after digestion of bacterium T cell binds to activated macrophage Section 40-2 Humoral Immunity Bacterial antigens also stimulate B cells Plasma cell produces large amounts of antibody proteins, released into the bloodstream

Work in the group Discuss why you get chicken pox once during childhood