Cytopathology Challenge! Weekly Cases October 1st 2007.

Slides:

Advertisements

Similar presentations

These are actual cases to –Stimulate your reading –Test your knowledge of the material Look for the sound icon (often in the upper right hand corner.

Advertisements

July 21, year old female. Thin prep pap A) Reactive endocervical cells B) HSIL C) LSIL D) Squamous metaplasia E) ASCUS 1.

Cytology Training Program: Gyn Cytology Revision Exercise by Tony Chan

Week of March 30, year old female. Conventional pap A.Endocervical adenocarcinoma in situ B.Benign endometrial cells C.Viral changes consistent.

Week of August 18, year old female with omental tumors. Ascitic fluid. A) Malignant mesothelioma B) Squamous cell carcinoma C) Amoebiasis D)

GYN SPECIAL EDITION NUMBER 2

Hologic Proprietary © 2012 ThinPrep ® Pap Test Diagnostic Challenges and Differential Diagnoses.

Abnormal Vaginal Bleeding in a 56 year old Max Brinsmead PhD FRANZCOG May 2015.

Cervix Dr. Raid Jastania. Cervical Cancer Screening HPV infection Pre- Cancerous Dysplasia Cancer years.

Cytopathology Challenge!

Precancerous lesion of FGT

Cytopathology Challenge! Weekly Cases October 22th 2007 Pap Smear Special Edition!

Cytopathology: Technique and Interpretation

Benign and Malignant Lesions in Respiratory Cytology

Chapter 4 Essential Concepts in Molecular Pathology Companion site for Molecular Pathology Author: William B. Coleman and Gregory J. Tsongalis.

Cancer Genetics Genetic Disorder. What are cancer genetics? Many cancer-predisposing traits are inherited in an autosomal dominant fashion, that is, the.

MHD II Laboratory Session Cytology APRIL 24, 2014.

Cellular adaptations of growth:  Cellular adaptations are reversible changes in size number funchion of cell in response to change in their environment.

Caring for the Reproductive System. Female Vulvovaginitis Vulvovaginitis –Inflammation or infection of the vagina –Caused when irritating substances enter.

Abnormal Pap in Pregnancy Alexander Burnett, MD Division Gyn Oncology, UAMS April, 2006.

SoftPAP® A Novel Collection Device for Cervical Cytology.

CIN and mimics Dr Michael Coutts Consultant Gynaecological Pathologist

PANCREATIC CANCER.

Human Biology Sylvia S. Mader Michael Windelspecht

Cytopathology Challenge! Weekly Cases September 24 th 2007.

September 1 st, year old female, FNA of parotid A.Benign salivary gland tissue B.Pleomorphic adenoma C.Warthin’s tumor D.Adenoid cystic carcinoma.

Cytology Weekly Cases September 17th 2007.

Oct 31, y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary.

Cervical Intraepithelial Neoplasm

Pancreatic Tumors Unknown Cases.

HUMAN REPRODUCTION, SEXUALITY AND INTIMACY. Caring for the Female Reproductive System  The most common problems are as follows: Vulvovaginitis - When.

August 1st, year old female. ThinPrep pap A.Trichomonas B.Lactobacillus C.Atrophy D.Bacterial vaginosis E.Artifact 1.

Case 1 Diagnostic possibilities Your diagnoses (%) Small cell carcinoma 4 Adenoid cystic carcinoma 30 Carcinoid49 No answer DIAGNOSTIC CYTOLOGY SEMINAR.

Cytopathology Challenge!

Path 822: Experimental Cancer Diagnostics & Therapeutics: PATHOLOGY OF TUMOURS Sandip SenGupta, M.D. Professor of Pathology September 2005.

17 th century microscopes In The Name of God PARISA REZAEI,M.D.,AP.CP.

CASE 1: FNA OF A LARGE GOITRE Roberto Dina, MD Cytology Dept of Histopathology Hammersmith Hospital London (U.K.)

1 Cytology Cases September 10, Thinprep Pap (28 year old) A. AGC B. Reactive Endocervical Cells C. Atrophy D. HSIL E. Endometrial.

Week of September 29, year old female. ThinPrep pap A.Lactobacillus B.Gonorrhea C.Trichomonas D.Bacterial Vaginosis E.Artifact 1.

Dec 12, y/o with ThinPrep pap: 1.LSIL 2.HSIL 3.Candida 4.Leptothrix 5.Actinomycetes 1.

Oct 17, year old male s/p TURP. Bladder wash A.High grade TCC B.Low grade TCC C.Instrumentation effect D.Sarcoma E.Nematode 1.

NEOPLASIA CASES. CASE 1 A 20 year old female presented with a round mobile breast lump. She has no family history of breast cancer Question : What test.

Cytopathology Challenge! Weekly Cases October 15th 2007.

March 13, y/o female. FNA of thyroid. 1 Hashimoto’s thyroiditis Lymphocytes mixed with follicular cells.

Cytopathology Challenge!

Cytopathology Feb Cytopathology at cellular level Study of pathological changes at cellular level. fluid or free cells Samples are fluid or.

KCP-771 ( 제출자 ) 원자력병원 R3 허일영. History  71 세 여자환자  6 개월 전부터 운동시 호흡곤란  2 주일 전부터 호흡곤란이 악화  흉부단순촬영에서 오른쪽 폐에 흉수와 무기폐.

Cytopathology Feb

GS Case M/53 S Small intestine, segmentectomy.

Interesting Case Presentation Written by: Neil Blackwell This case was provided by: GynaePath – Douglass Hanly Moir Pathology, Sydney, Australia.

Oncology Topic-Adenocarcinoma, Lung

Cytopathology Laboratory

Seromucinous Tumor of the Ovary

Non-Communicable Diseases Lesson 7

Tumor Marker Tests.

Angela Lignelli, MD, Alexander G. Khandji, MD Neurosurgery Clinics

Oncogene at last—c-Jun promotes liver cancer in mice

Cytopathology Challenge!

Find 4 A + 2 B if {image} and {image} Select the correct answer.

Genomic alterations in non–small cell lung cancer, breast cancer, and colorectal cancer. Genomic alterations in non–small cell lung cancer, breast cancer,

Significance of P53 and Rb protein expression in surgically treated non-small cell lung cancers Yung-Chie Lee, MD, PhD, Yih-Leong Chang, MD, Shi-Ping.

Comparison of C1-and Pap-staining

Thyroid lung metastasis diagnosed 47 years after thyroidectomy1

Interstitial tumor-associated macrophages combined with tumor-derived colony- stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non–small.

Volume 139, Issue 5, (November 2009)

Thoracoscopic Fine-Needle Aspiration of Solitary Pulmonary Nodules

Gastrointestinal imaging: Endoscopic ultrasound

Complete Resection of Oligorecurrence of Stage I Lung Adenocarcinoma 19 Years After Operation Dai Sonoda, MD, Masashi Mikubo, MD, Kazu Shiomi, MD, PhD,

EGFR delE709_T710insD: A Rare but Potentially EGFR Inhibitor Responsive Mutation in Non–Small-Cell Lung Cancer Allison Ackerman, MD, Michael A. Goldstein,

Presentation transcript:

Cytopathology Challenge! Weekly Cases October 1st 2007

66 year old female. BAL A.Oral contaminant B.Squamous metaplasia C.Inflammatory change/reactive D.Suspicious for tumor E.Squamous Cell CA

54 year old female with liver transplant BAL for respiratory distress/infiltrates. A.Dirofilaria B.Strongyloides C.Enterobius D.Trichuris E.Ascaris

23 year old female. ThinPrep pap. A.Reactive B.ASCUS C.LSIL D.HSIL E.Squamous metaplasia

78 year old male. BAL. A.Pulmonary macrophages B.Atypical C.Suspicious D.Positive for tumor E.Reactive

38 year old female. ThinPrep Pap A.Squamous metaplasia B.Reactive endocervical cells C.ASCUS D.LSIL E.HSIL

57 year old female. Ovarian mass. Pelvic washing in OR. A.Reactive mesothelial cell B.Lymphoma C.Histiocyte D.Consistent with Ovarian CA E.Artifact

45 year old female. Corneal scrape GMS A.Histoplasmosis B.Histoplasmosis C.PCP D.Candida E.Acanthameba

72 year old female. Common bile duct brushing A.Reactive B.Atypical C.Suspicious D.Positive E.Epithelial Cell Abnormality

38 year old female with thyroid nodule. FNA Pap stain. A.RET/PTC2 is the most common mutation B.RET/PTC1 is the least common mutation C.RET/PTC rearrangements are specific to this tumor D.These tumors are CK7-/CK20+ E.The proto-oncogene for this tumor is on 10q11.2

26 year old female. ThinPrep Pap. A.Squamous metaplasia B.Reactive endocervical cells C.Atrophic changes D.ASCUS E.LSIL

Answers 1.Squamous cell Ca Large tumor cell with features of squamous cell 2.Strongyloides Coolest case of the week! 3.LSIL Koilocytes 4.Positive for tumor Non-small cell lung CA – probably squamous again. 5.HSIL NC ratio is increased, not koilocytes. 6.Consistent with ovarian cancer Tumor cell in peritoneal washing – used for staging purposes. 7.Candida Budding yeast 8.Positive for tumor Likely an adenocarcinoma, I put an image of some “Normal” reactive epithelium from the case in the image in the bottom right corner for comparison to the tumor in the rest of the images 9.Papillary thyroid tumor. Correct answer is “E” Check out Rosai page 535…. 10.Squamous metaplasia Normal finding