Jeremy Leibfried Tyler Gronli Fasciola hepatica Jeremy Leibfried Tyler Gronli
Introduction Phylum: Platyhelminthes Flat worm Liver fluke Effects sheep, cattle, and sometimes humans Tyler
Tyler
Interesting Facts Eggs found in mummies 1st fluke or trematode to be reported 1379 Reported in Publication (Le Bon Berger) 1st discovered in sheep Tyler
F. hepatica Definitive host: Intermediate host Geographic Range Sheep Cattle Humans (Accidental) Other Mammals Intermediate host Fresh Water Snail Geographic Range Cosmopolitan; anywhere sheep and cattle are raised Tyler
Morphology Adult fluke Flat leaf like body 20-30mm long 8-15mm wide Tyler
Site of Infection Ingestion Metacercariae Ex-cyst in Duodenum Burrows through Intestinal Wall Enters Peritoneal Cavity Migrates to Liver Jeremy
Jeremy
Miracidia Egg Jeremy Cercariae Metacercariae
Symptoms Abdominal Pain Anemia Hepatic Tenderness Hepatomegaly resulting from Edema Intermittent Fever Jaundice Lethargy Nausea Prolonged High Fever Secondary Infections Vomitting Tyler
Symptoms Acute Chronic Halzoun More common in sheep 10,000+ Metacercariea consumed at one time Dramatic Liver Inflamation, Frequently Resulting in Death Chronic More Common and Rarely Fatal Nonspecific Symptoms Halzoun Eating raw, infected liver Infects pharynx Causes swelling and obstructs breathing Tyler
Diagnosis Stool Samples Duodenal or Biliary Aspirate Antibody Test Yellow-Brown Eggs Eggs Don’t Show for 4 Months Duodenal or Biliary Aspirate Antibody Test Can detect 2 Weeks After Infection Ultrasound Visualize Adults in Bile Duct CT Scan Reveals Burrows in Liver Jeremy
Treatment Bithional Triclabendazole Surgery Highly Effective Large Dose High Cost Long Treatment Period Triclabendazole Easier to Use 1-2 Oral Doses in 24 hrs Virtually 100% Effective Surgery Jeremy
Control Methods Eduaction Moluskicide Cheapest and Most Cost Effective Way Wash Aquatic Vegetables in 6% Vinegar for 5-10 minutes Better herding practices Keep herds away from aquatic areas Moluskicide Controls Intermediate Snail Host Jeremy
Jeremy