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Nematohelminthes (Round worms)

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Presentation on theme: "Nematohelminthes (Round worms)"— Presentation transcript:

1 Nematohelminthes (Round worms)
Helminthology Phylum Phylum Platyhelminthes (Flat worms) + Nematohelminthes (Round worms) Class Trematoda (Flukes) Class Class Ceastoda (Tape worms) Nematoda Genus : Echinococcus Species : E. granulosus & E. multilocularis

2 Echinococcosis or Hydatidosis

3 1 Echinococcus granulosus cystic echinococcosis 2 Echinococcus multilocularis alveolar echinococcosis

4 Human Echinococcosis is caused by the larval stages of cestodes (tapeworms) of the genus Echinococcus Both have 3 proglottids, hooks and suckers

5 Echinococcus granulosis -
The Hydatid Tapeworm Major pathology - hydatid cysts in the brain. Can grow to size of a coconut and contain as much as two liters of fluid. Pressure necrosis of tissue can result from larger cysts. Most commonly found in liver, but can develop anywhere, including in bone.

6 Adult Tapeworm Body is separated into 3 sections
Scolex with 4 sukers & rostellum armed with double crown of hooks

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9 Ecchinococcus granulosus stages

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14 Definitive Host/Intermediate Host
Echinococcus granulosus: Definitive Host: dogs,Wolves and other carnivores Intermediate Host: mammals, including humans or herbivorous species( Sheep,Horses,Camels,Pigs) Echinococcus multilocularis: Definitive Host: mainly foxes but dogs, cats, coyotes and wolves also Intermediate Host: small rodents, rarely humans

15 Geographic Distribution:
E. granulosus Worldwide More frequent in rural, sheep raising areas E. multilocularis Occurs in northern hemisphere This includes central and northern Europe, Asia, and North America Most frequently found in northern states

16 Life Cycle of E granulosus

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18 Symptoms: E. granulosus Can remain silent for years
It is the enlarging cysts that cause symptoms in organs Hepatic involvement (abdominal pain, mass in the hepatic area, biliary duct obstruction) Pulmonary involvement (chest pain, Cough, hemoptysis) Brain, bone, and heart Rupture of cyst (fever, hives, pus, anaphylactic shock, and the cyst spreads throughout body cavity)

19 E. Multilocularis Affects the liver as a slow growing destructive tumor Abdominal pain, biliary obstruction, and sometimes metastatic lesions in lungs and brain are common symptoms Causes alveolar echinococcosis

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21 Diagnosis Imagery Immunodiagnostic techniques Microscopy
Hydatids are found during X-radiography, ultrasonography, CAT scans Immunodiagnostic techniques Generally less sensitive then imagery Microscopy Fluid aspirated from hydatid cyst will show many protoscolices

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23 Infective stage: Egg Found in dog feces Resembles Taenia eggs

24 Imaging Studies: Plain radiography Ultrasound examination CT scaning
MRI

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26 Treatment Most effective and common type of treatment is surgery to remove the parasite mass Medication after surgery may be necessary to keep the cyst from recurring Drug of choice is albendazole for E. granulosus Drug of choice is albendazole and mebendazole for E. multilocularis

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29 Prevention in Humans Minimize risk of egg ingestion
Wash fruits and vegetables Wash hands frequently Avoid untreated water sources Do not handle wild carnivores or their carcasses Thoroughly cook meat before eating


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