Antibiotics Versus Conservative Surgery for Treating Diabetic Foot Osteomyelitis: A Randomized Comparative Trial Featured Article: José Luis Lázaro-Martínez,

Slides:

Advertisements

Similar presentations

IN THE NEXT FEW SLIDES YOU WILL SEE THE MIRACLE OF SURGICAL OFF-LOADING.

Advertisements

THE DIABETES PREVENTION PROGRAM RESEARCH GROUP*

Somdejprapinklao Hospital

Effects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity Featured Article: Ricardo V. Cohen, M.D., Jose C. Pinheiro, M.D.,

Individual Mindfulness-Based Cognitive Therapy and Cognitive Behavior Therapy for Treating Depressive Symptoms in Patients With Diabetes: Results of a.

Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy: A Randomized Double-Blind Trial of Saxagliptin Plus Dapagliflozin.

Diabetes and the Foot The Road to Amputation?

Six-Week Versus Twelve-Week Antibiotic Therapy for Nonsurgically Treated Diabetic Foot Osteomyelitis: A Multicenter Open-Label Controlled Randomized Study.

The Effect of a Diabetes-Specific Cognitive Behavioral Treatment Program (DIAMOS) for Patients With Diabetes and Subclinical Depression: Results of a Randomized.

New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 2 Diabetes Using Basal and Mealtime Insulin: Glucose Control and Hypoglycemia.

Liraglutide and the Preservation of Pancreatic β-Cell Function in Early Type 2 Diabetes: The LIBRA Trial Featured Article: Ravi Retnakaran, Caroline K.

Association Between Diabetes, Obesity, and Short-Term Outcomes Among Patients Surgically Treated for Ankle Fracture by Matthew J. Cavo, Justin P. Fox,

Efficacy and Safety of Dulaglutide Added Onto Pioglitazone and Metformin Versus Exenatide in Type 2 Diabetes in a Randomized Controlled Trial (AWARD-1)

Improved Glucose Control With Weight Loss, Lower Insulin Doses, and No Increased Hypoglycemia With Empagliflozin Added to Titrated Multiple Daily Injections.

PICO By: Victoria A. Volway

Ranjith Babu, MS 1 Jonathan Choi, MD 1 Adam Back, MD 1 Vijay Agarwal, MD 1 Matthew Hazzard, MD 1 Beatrice Ugiliweneza, MSPH PhD 2 Chirag G. Patil, MD MS.

An Automated Internet Behavioral Weight-Loss Program by Physician Referral: A Randomized Controlled Trial Featured Article: J. Graham Thomas, Tricia M.

1 Journal Club Alcohol, Other Drugs, and Health: Current Evidence July–August 2012.

A Retrospective Analysis of the Impact of Intramuscular Antibiotics for the Treatment of ‘Borderline’ Foot Infections - an Admission Avoidance Strategy.

Spinal Cord Stimulation and Pain Relief in Painful Diabetic Peripheral Neuropathy: A Prospective Two-Center Randomized Controlled Trial Featured Article:

Birga Terlunen-Traboldt ENT-Journal Club Need for Neck dissection after Radiochemotherapy? A study of the French GETTEC Group Vedrine P;Thariat J;Hitier.

Incidence of Pancreatitis and Pancreatic Cancer in a Randomized Controlled Multicenter Trial (SAVOR-TIMI 53) of the Dipeptidyl Peptidase-4 Inhibitor Saxagliptin.

Rapid Rise in Hypertension and Nephropathy in Youth With Type 2 Diabetes The TODAY clinical trial Featured Article: TODAY Study Group* Diabetes Care Volume.

JOURNAL REPORT CHOLELITHIASIS PGI Alexander L. Gonzales II DOH – PCSCH 2012.

Glycemic Control in Simultaneous Islet-Kidney Versus Pancreas-Kidney Transplantation in Type 1 Diabetes: A Prospective 13-Year Follow-up Featured Article:

Phase II Presurgical Feasibility Study of Bevacizumab in Untreated Patients with Metastatic Renal Cell Carcinoma Jonasch E et al. Journal of Clinical Oncology.

Ali Ardestani, David Rhoads, Ali Tavakkoli

The Bone & Joint Program at the University of Louisville: The Bone and Joint Infection (BAJIO) Database Diana Christensen MD, Julie Harting PharmD, Cheick.

Hyperbaric Oxygen Therapy

Targeted Intraoperative Radiotherapy versus Whole Breast Radiotherapy for Breast Cancer (TARGIT-A Trial): An International, Prospective, Randomised, Non-Inferiority.

A New Oral Direct Thrombin Inhibitor, Dabigatran Etexilate, Compared With Enoxaparin for Prevention of Thromboembolic Events Following Total Hip or Knee.

Metabolic Effects of Bariatric Surgery

METHODS Efficacy was measured by comparing MDT to traditional treatment (i.e., antibiotics and surgical debridement). Levels of evidence included case-

Randomized Controlled Trial of Intensive Versus Conservative Glucose Control in Patients Undergoing Coronary Artery Bypass Graft Surgery: GLUCOCABG Trial.

Impact of early surgery vs conventional treatment for infective endocarditis on mortality and embolic events: data from EASE trial Prospective RCT ( );

Delivering clinical research to make patients, and the NHS, better OG neoadjuvant therapy Brachytherapy Stephen Falk dd/mm/yyyy.

Maternal Efficacy and Safety Outcomes in a Randomized, Controlled Trial Comparing Insulin Detemir With NPH Insulin in 310 Pregnant Women With Type 1 Diabetes.

What’s new in diabetes foot care? NICE and beyond Dr Simon Ashwell Consultant Diabetologist The James Cook University Hospital Middlesbrough.

Safety and Efficacy of Sitagliptin Therapy for the Inpatient Management of General Medicine and Surgery Patients With Type 2 Diabetes A pilot, randomized,

AIN III and Perianal skin intraepithelial neoplasia.

Efficacy and Safety of Canaglifozin, a Sodium- Glucose Cotransporter 2 Inhibitor, as Add-on to Insulin in Patients With Type 1 Diabetes Featured Article:

Journal Club Alcohol, Other Drugs, and Health: Current Evidence November-December, 2015.

THE DIABETES PREVENTION PROGRAM RESEARCH GROUP*

Evaluation of Current Eligibility Criteria for Bariatric Surgery Diabetes prevention and risk factor changes in the Swedish Obese Subjects (SOS) study.

Intensive Versus Intermediate Glucose Control in Surgical Intensive Care Unit Patients Featured Article: Takehiro Okabayashi, Yasuo Shima,Tatsuaki Sumiyoshi,

R1 강민혜 / prof. 전숙. Introduction Patients with type 2 diabetes have a greatly increased risk of cardiovascular events. The morbidity and mortality related.

Bariatric Surgery for T2DM The STAMPEDE Trial. A.R. BMI 36.5 T2DM diagnosed age 24 On Metformin, glyburide  insulin Parents with T2DM, father on dialysis.

Philip R. Schauer, M.D., Deepak L. Bhatt, M.D., M.P.H., John P. Kirwan, Ph.D., Kathy Wolski, M.P.H., Stacy A. Brethauer, M.D., Sankar D. Navaneethan, M.D.,

Liraglutide Reduces CNS Activation in Response to Visual Food Cues Only After Short-term Treatment in Patients With Type 2 Diabetes Featured Article: Jennifer.

Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal- cell carcinoma after radical nephrectomy: phase III,

Diabetic Foot Care – helping commissioners and providers to

Marina Yiasemidou, MBBS, MSc CT1 General Surgery

CHARACTERISTICS AND OUTCOME OF MAJOR LOWER LIMB AMPUTATIONS IN A TERTIARY CARE HOSPITAL Nishanthan A A, Sarangan S, Kalaventhan P, Prasath S, Gooneratne.

Clinical evaluation of recombinant human platelet – derived growth factor for the treatment of lower extremity diabetic ulcers David L. Steed, MD, the.

Alcohol, Other Drugs, and Health: Current Evidence

The ADEMEX Trial Adequacy of PD in Mexico Reference

Fig 1: Microscopic Spindle shaped MSCs Fig 2: Method of MSCs Injection

Emily Decker1, Ania Mejsak1, Alan Askari2, Shirley Chan1

Purpose Infective endocarditis (IE) which is an uncommon disease in pediatric patients can cause significant morbidity and mortality. IE is treated with.

Clinical Microbiology and Infection

Case 1: Introduction. Adjuvant Therapy: Should It Be Considered in Older Patients With NSCLC?

SUSTAIN-6 Trial design: Patients with DM2 at high risk for CV events were randomized in a 1:1:1:1 fashion to either semaglutide 0.5 mg, semaglutide 1 mg,

Trends and determinants of costs associated with the inpatient care of diabetic foot ulcers Caitlin W. Hicks, MD, MS, Shalini Selvarajah, MD, MPH, Nestoras.

EXPLORE Trial design: Patients with STEMI treated with primary PCI and with evidence of noninfarct artery chronic total occlusion (CTO) were randomized.

Ali F. AbuRahma, MD Journal of Vascular Surgery

Sensitivity analysis: random-effects model of the risk of lower extremity amputation (LEA) in people with diabetes associated with depression compared.

An algorithm depicting the basic approach to the Charcot foot

The incidence of insulin-treated type 1 diabetes in the first 35 years of life. The incidence of insulin-treated type 1 diabetes in the first 35 years.

Presentation data from US VICTORY Consortium

Changes in glycated hemoglobin (HbA1c) levels after 12 weeks’ treatment with lixisenatide (according to dose increase regimen) or placebo. Changes in glycated.

Presentation transcript:

Antibiotics Versus Conservative Surgery for Treating Diabetic Foot Osteomyelitis: A Randomized Comparative Trial Featured Article: José Luis Lázaro-Martínez, Javier Aragón- Sánchez, and Esther García-Morales Diabetes Care Volume 37: March, 2014

STUDY OBJECTIVE To compare the treatment outcomes of diabetic foot osteomyelitis in patients treated exclusively with antibiotics versus patients who underwent conservative surgery Follow-up occurred for 12 weeks after healing Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:

STUDY DESIGN AND METHODS Prospective randomized comparative trial was carried out in diabetes patients with neuropathic foot ulcers complicated by osteomyelitis Patients were randomized into two groups: Antibiotics group (AG) Surgical group (SG) Antibiotics were given for 90 days in AG SG received conservative surgery with postoperative antibiotic treatment for 10 days Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:

RESULTS 18 patients (75%) achieved primary healing in AG and 19 (86.3%) in SG Median time to healing was 7 weeks in AG and 6 weeks in SG Conditions of four patients from AG worsened (16.6%), and they underwent surgery Three patients from SG required reoperation No difference was found between the two groups regarding minor amputations Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:

CONCLUSIONS Antibiotic therapy and surgical treatment had similar outcomes in terms of healing rates, time to healing, and short-term complications Lázaro-Martínez J. L. et al. Diabetes Care 2014;37: