CERVICAL/VAGINAL CYTOLOGY

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CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

INTRODUCTION&HISTORY Dr.George N.Papanicolaou(1883-1962) Dr.Aurel A.Babes 1927 Dr.George Papanicolaou&Dr.Herbert F.Traut 1943

Microscopic Anatomy Vagina:Non-Keratinizing Stratified Squamous Cervix: Ectocervix:Non-Keratinizing Stratified Sqamous Endocervix:Tall Columnar Epithelium ُSquamocolumnar Junction Original Transformation zone

ASSESSMENT OF QUALITY OF SMEARS

THE BETHESDA SYSTEM Statement of specimen adequacy Epithelial cell abnormalities Others

ADEQUACY OF THE SPECIMEN Satisfactory for evaluation Unsatisfactory

Epithelial cell abnormalities Low grade intraepithelial lesion(LSIL) -CIN1(mild dysplasia) & HPV changes High grade intraepithelial lesion -CIN2,CIN3,CIS(carcinoma insitu)

LSIL

LSIL,HPV changes

HSIL