Designing, Executing, Reusing and Sharing Workflows: Taverna and myExperiment Supporting the in silico Experiment Life Cycle Katy Wolstencroft Paul Fisher University of Manchester

Workflow Environments Taverna Workflow design and execution environment Access to local and remote resources and analysis tools Automation of data flow Iteration over large data sets 50,000 downloads Used by 350+ organisations myExperiment Workflow sharing and publishing environment Web 2.0 Social network Sharing workflows, expertise, knowledge and/or data 964 users 301 workflows

Taverna For bioinformaticians, NOT biologists Used for Data gathering annotation pipelines, data integration, model population Data analysis microarray, proteomics, Data mining and knowledge integration Ontology building

myExperiment Supports bioinformaticians but also enables biologists to run ready-made workflows Intended for ANY workflows, not just Taverna Already working with Triana Allows “just enough” sharing between groups/communities Who can look at your workflow Who can download your workflow Who can modify your workflow Who can run your workflow

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In Silico Life Cycle

Taverna In Silico Life Cycle

my Grid Development Started 2001 – EPSRC E-Science project 2005 – OMII-UK myExperiment - started 2007 Open Source Funded until after 2010

my Grid Development

Demo

Current work

Speed and Scalability Taverna 2 enactor Support for long running workflows Large scale data – industrial bioinformatics Data streaming Passing data by reference Integration with established computing platforms

Extensibility and Ease of Use Drag and drop workflow building More content – greater pool of workflows in myExperiment More components – gathering together commonly used groups of services Shim libraries – for combining incompatible services Service and workflow annotation checking

Curation by Experts Curation by the Community Automated Curation refine validate refine validate Curation by Developers seed refine validate seed BioCatalogue Joint Manchester-EBI

Toolkits “Taverna Inside” Workflows under the hood e-Laboratories (portals) Systems Biology, e-Health Dashboards configurable platforms for small biological communities Visualisation clients that call workflows in the background

UTOPIA Pettifer, Kell, University of Manchester

Toolkits “Taverna Inside” Workflow development pipeline Workflows developed by bioinformaticians Enacted locally E-Labs, Dashboards and 3 rd party clients Social support for bioinformaticians to find and reuse workflows and expertise Access to ready made workflows for biologists Workflows enacted locally Taverna remote execution service (T-Rex) Social support to find and reuse workflows and expertise CONFIGURABLE access to ready made workflows for biologists Workflows embedded in applications and combined with data management systems

Come and see us Booth 20 Manchester Bioinformatics Development is user driven – we need your input! Try out myExperiment Try out Taverna and T2 Try out the new drag and drop interface Do you want workflows behind your tools? ….and come and tell us what you think