Gail Vanairsdale Global Clinical Education Manager Enlite Sensor Insertion

2 | For Internal Use Only Enlite Sensor Insertion Objectives 1 Identify necessary supplies and system components 2 Describe appropriate insertion sites and technique for inserting Enlite sensor Complete successful Enlite sensor insertion into model abdomen 3 At the completion of this session, participants will:

3 | For Internal Use Only Patient Training Video

4 | For Internal Use Only Gather Supplies Enlite™ Sensor Enlite™ Serter MiniLink® transmitter Alcohol wipe Sensor overtape Sharps container

5 | For Internal Use Only Prepare to Insert Wash your hands. 7B7B 1

6 | For Internal Use Only Prepare to Insert 5 centimeters from your injection site 5 centimeters (2 inches) from your navel 5 centimeters (2 inches) from your insulin pump infusion site 7.5 centimeters (3 inches) from any manual insulin injection site 2 Select appropriate insertion site Note: Clinical trials for glucose sensors were performed on sensor inserted in the areas shown above

7 | For Internal Use Only Prepare the Site Clean insertion site with alcohol. Let it air dry. 3

8 | For Internal Use Only Open the Sensor Package Open the sensor package. Remove the pedestal from the package. Place the pedestal on a flat surface, such as a table. 4 5

9 | For Internal Use Only Push Serter onto Pedestal Push the Serter down until the base of the Serter sits flat on the table. 6 7

10 | For Internal Use Only Detach Serter from Pedestal To detach the Serter from the pedestal, place two fingers on the pedestal arms and slowly pull the Serter straight up. Do not detach the pedestal from the Serter in mid-air, as this might damage the sensor. 8

11 | For Internal Use Only Place Serter on Site Place the base of the Serter flat against your insertion site. 9 WARNING: Never point a loaded Serter toward any body part where insertion is not desired

12 | For Internal Use Only Inserting the Enlite Sensor 10A 10B 10C 10D

13 | For Internal Use Only Remove Needle Housing 11 Gently hold the base of the sensor against the skin. Hold the needle housing at the top and slowly pull straight out, away from the sensor. Dispose of the needle housing in a sharps container after a single use. Do not clean or resterilize, and do not try to extract the needle from the needle housing. WARNING: If bleeding occurs, apply steady pressure using sterile gauze or a clean cloth for up to three minutes

14 | For Internal Use Only Sensor Adhesive Tape Straighten the sensor adhesive tape so that it lies flat against the skin While holding the sensor in place, gently lift the adhesive tab. Carefully remove the bottom piece of white paper from under the adhesive pad. Press the adhesive against the skin.

15 | For Internal Use Only Apply the Sensor Overtape 14 3 Before connecting the device, apply overtape. Do not cover the adhesive tab (1) or sensor connectors (2) with overtape (3).

16 | For Internal Use Only Connecting the Device Connect the device to the sensor. NOTE: Overtape is not shown in steps 15-19

17 | For Internal Use Only Cover with Sensor adhesive tab Cover the device with the sensor adhesive tab.

18 | For Internal Use Only Skill Practice Table lead will guide you through process Two participants at a time will insert sensors, apply overtape, and attach MiniLink, using model abdomen. Do NOT insert sensors into yourself, each other, or other living beings When you have completed your practice, remove your sensors from models and place into sharps container. The next pair of participants will then insert sensors.