PRODUCT – PACKAGE INTERATION 4/22/2017 YHA_ITP

Product – Package Interaction Relationship between package and food inside the package Package Food 4/22/2017 YHA_ITP

FOOD – PACKAGE INTERACTION PHENOMENE IS TRANSFER OR MIGRATION OF THE MOST IMPORTANT FOOD – PACKAGE INTERACTION PHENOMENE IS TRANSFER OR MIGRATION OF COMPOUNDS FROM PACKAGE TO FOOD PRODUCTS INSIDE THE PACKAGE ESPECIALLY THE PACKAGE BASED ON PLASTIC MATERIALS 4/22/2017 YHA_ITP

High molecular weight components : Macromoleculer (polymers) PLASTIC CONTAIN : High molecular weight components : Macromoleculer (polymers) Low molecular weight components: Residual monomer Oligomers Additives  plasticizers antioxidants antiblock antistatic uv absorber filler 4/22/2017 YHA_ITP

IN FOOD PACKAGING REGULATIONS THE TERM MIGRATION IS USED TO DESCRIBE THE TRANSFER OF SUBSTANCES FROM THE PACKAGE (USUALLY A PLASTIC ARTICLE) TO THE FOODSTUFF 4/22/2017 YHA_ITP

MIGRATION OCCURS DURING Processing Storage Distribution CAUSING : Objectionable results Toxicological concerns 4/22/2017 YHA_ITP

OBJECTIONABLE RESULTS: Quality deterioration Objectionable odor formation Flavor deterioration TOXICOLOGICAL CONCERNS : Toxic substances migration to the foods Some substances are carcinogens 4/22/2017 YHA_ITP

TYPES OF MIGRATION GLOBAL MIGRATION SPECIFIC MIGRATION 4/22/2017 YHA_ITP

GLOBAL MIGRATION Total quality of substances migrating from the package into the contacting phase (foodstuffs) Toxic substances Non Toxic Substances 4/22/2017 YHA_ITP

SPECIFIC MIGRATION Transfer into foods of those components known or deemed potentially hazardous to human health 4/22/2017 YHA_ITP

PLASTIC COMPONENTS POTENTIALLY HAZARDOUS TO HUMAN HEALTH : Monomer: Vinyl chloride Acrylonitrile Styrene Vinylide chloride Additives: Plasticizers Antioxidants 4/22/2017 YHA_ITP

LEGAL REGULATION IN THE USA IS THE PLASTIC PACKAGING MATERIAL COMING IN CONTACT WITH THE PRODUCT APPROVED BY THE FOOD AND DRUG ADMINISTRATION (FDA) FOR FOOD PACKAGING USAGE DOES THE PACKAGING MATERIAL CONTAIN ONLY FDA APPROVED ADDITIVES IN THE PERMITTED LEVELS 4/22/2017 YHA_ITP

LEGAL REGULATION IN THE USA (Continued) TO WHAT EXTENT DO TRACE AMOUNTS OF SOLVENTS REACTION AND DEGRADATION BY PRODUCTS, ADDITIVES, MONOMERS AND OLIGOMERS MIGRATE FROM THE PACKAGE INTO THE CONTACT PHASE? HOW GREAT IS THE SUM OF THE WEIGHT OF ALL CONSTITUENT MIGRATING FROM THE PACKAGING MATERIAL INTO THE PRODUCT TO BE PACKAGE? 4/22/2017 YHA_ITP

LEGAL REGULATION IN THE USA (Continued) WHAT IS THE RISK TO THE GENERAL PUBLIC AS A RESULT OF MIGRATION OF MOITIES FROM THE PACKAGING MATERIAL TO A CONTACT PHASE AND THEIR SUBSEQUENT INGESTION? 4/22/2017 YHA_ITP

METHODS OF DETECTION : GLOBAL MIGRATION: Gravimetry Radiolabelling SPECIFIC MIGRATION: Gas chromatography Others 4/22/2017 YHA_ITP

THANK YOU 4/22/2017 YHA_ITP