ORGANIZATION OF ANS-I By Dr.Sajid Hussain OBJECTIVES Recall the anatomic organization of ANS Discuss the synthesis, actions and degradation of neurotransmitters.

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Presentation transcript:

ORGANIZATION OF ANS-I By Dr.Sajid Hussain OBJECTIVES Recall the anatomic organization of ANS Discuss the synthesis, actions and degradation of neurotransmitters – ach & NA Explain cholinergic transmission Describe adrenergic transmission OBJECTIVES Recall the anatomic organization of ANS Discuss the synthesis, actions and degradation of neurotransmitters – ach & NA Explain cholinergic transmission Describe adrenergic transmission

Organization of Nervous system

Organization of ANS

ParasympatheticSympathetic OriginCranio-sacralThoraco-lumbar GangliaUsually terminal or embedded in the supplied organ Usually paravertebral in the sympathetic chain PreganglionicLongshort PostganglionicShortLong innervationMost organs receive dual innervation Control Almost all organs except B.V.Most of blood vessels Actions Usually localized Conserve energy and discharge (rest, digestion & waste removal) Usually generalized Stress( fight and flight)

Organization of ANS

Actions of Parasymthetic Ach & NA

Synthesis, Storage, release & degradation of Ach

Synthesis of Ach

Storage, release and degradation

Cholinergic transmission

Synthesis, Storage, release & degradation of NA

Reuptake of catecholamines

Adrenergic transmission

summary

References Lippincott’s Illustrated review of pharmacology – 4 th edition Basic & clinical pharmacology, Bertram G katzung- 12 th edition Goodman & Gilman’s -pharmacology Lippincott’s Illustrated review of pharmacology – 4 th edition Basic & clinical pharmacology, Bertram G katzung- 12 th edition Goodman & Gilman’s -pharmacology

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