LRI Validation Suite WG Update for LRI Pilot WG May 1, 2012

Phase 1 Core Test Messages Profile Type Short DescriptionMessage Type NG Minimally Populated SED Rate message - Final Results Minimum GU Minimally Populated SED Rate message - Final Results Minimum NG Typically Populated SED Rate message - Final Results Typical-Final GU Typically Populated SED Rate message - Final Results Typical-Final NG Typically Populated SED Rate message - Corrected Results Typical-Corrected GU Typically Populated SED Rate message - Corrected Results Typical-Corrected NG Maximally Populated SED Rate message - Final Results Maximum GU Maximally Populated SED Rate message - Final Results Maximum NG Rejected SED Rate Message (No OBX segment; OBR.25 = X) Specimen Reject GU Rejected SED Rate Message (No OBX segment; OBR.25 = X) Specimen Reject NG Typically Populated CBC message - Final Results Typical GU Typically Populated CBC message - Final Results Typical NG Typically Populated Lipid Panel message - Final Results Typical GU Typically Populated Lipid Panel message - Final Results Typical NG Culture-Campylobacter jejuni, Salmonella, Shigella - Parent - Preliminary NG-Parent-Linking GU Culture-Campylobacter jejuni, Salmonella, Shigella - Parent - Preliminary GU-Parent-Linking NG-RU Culture-Campylobacter jejuni, Salmonella, Shigella - Parent/Child Susceptibility - Final NG-RU-Parent-Child-Linking GU-RU Culture-Campylobacter jejuni, Salmonella, Shigella - Parent/Child Susceptibility - Final GU-RU-Parent-Child-Linking NG-RN Culture-Campylobacter jejuni, Salmonella, Shigella - Parent/Child Susceptibility - Final NG-RN-Parent-Child-Linking GU-RN Culture-Campylobacter jejuni, Salmonella, Shigella - Parent/Child Susceptibility - Final GU-RN-Parent-Child-Linking

Phase 2 Test Messages* Anatomical Pathology/Surgical Pathology Study – Example of A4 result – Two draft messages completed (Skin biopsy and Inguinal Lymph Node biopsy) HIV 1 Ab [Presence] – Example of Reflex testing – Draft message completed A toxicology test – Example of Screening followed by Reflex testing – Draft Screening message for Amphetamines [Presence] in Urine with negative result completed; Reflex draft message needed – Other test messages could include urine test for Cannabinoids, Cocaine, Opiates, Phencyclidine *Will start including in Validation Tool and Test Plans in June 2012

Phase 2 Test Messages (cont’d) Cytology Panel with four components – Example of combination of A2 and A4 results in a panel Specimen source (identifier) in cervical or vaginal smear or scraping by Cyto stain – example of A2 result Cytology report of cervical or vaginal smear or scraping Cyto stain thin prep – example of A4 result Recommended follow-up (identifier) in cervical or vaginal smear or scraping by Cyto stain – example of A2 result Cytology study comment on cervical or vaginal smear or scraping by Cyto stain – example of A4 result – Draft message needed

Phase 2 Test Messages (cont’d) Human Genome – CFTR gene mutations found [Identifier] – Example of A3 result – Draft message completed Complete Urinalysis (panel test) – lowest priority test – Example of A2 result Draft message completed - to be modified using “+” or “++ “for bilirubin result value – Example of A4 results Urine sediment comments

Needed from Pilots Testers and feedback for current version of Validation Suite tool Volunteers for 1-on-1 Webex testing – Especially EHR systems – Validation Suite to be ready in June 2012