Importance of Vitamin D Where is your level at on the scale? Presented by Andrea Fennell Kaplan University HW499 April 18, 2011

Introduction  Vitamin D Overview  Medical Importance  Are you deficient?  Reasons many are deficient  Video discussing Chronic disease prevention  Vitamin D and Cancer  Role in Heart Disease

Vitamin D Overview  Steroid – structured hormone  Is produced photochemcically or consumed via dietary or supplementation  Fat Soluble/found naturally but not in many foods  Exists in 2 forms that matter to humans: Vitamin D2 & Vitamin D3  Can be obtained from sun exposure(sunlight produces syntheisis)  Needed for bone growth/cell growth/ proper immune function  Reduces inflammation Ruxton, C. H., & Derbyshire E. (2009). Health impacts of vitamin D: are we getting enough? Nutrition Bulletin, 34 (issue 2), Retrieved from 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN= Nutrition Bulletinhttp://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=15&hid=15&sid=abb a78-864e- 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=

Medical Importance Why we should maintain adequate levels  Less chance of Cancers  Decreased Cardiovascular Disease  Better Osteoarthritis/Skeletal Health  Less Falls in Seniors  Lowered Autoimmune Disease risks  Decrease in Diabetes Type 1 & Type 2  Reduces inflammation  Less risks in Pregnancy  Must supplement with Lactation Avalier, E., & Delanaye, P., & Chapelle, J., Souberbielle J. (2009). Vitamin D current status and perspectives. Clinical Chemistry & Laboratory Medicine, 47(2), Retrieved from 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN= Clinical Chemistry & Laboratory Medicine 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=

Are you Deficient? nmol/L** ng/mL*Health status <30<12 Associated with vitamin D deficiency, leading to rickets in infants and children and osteomalacia in adults 30–5012–20 Generally considered inadequate for bone and overall health in healthy individuals ≥50≥20 Generally considered adequate for bone and overall health in healthy individuals >125>50 Emerging evidence links potential adverse effects to such high levels, particularly >150 nmol/L (>60 ng/mL) Office of Dietary Supplement National Institutes of Health Fact Sheet: Vitamin D. Retrieved from

Video: Vitamin & Prevention of Chronic Disease Speaker is Michael F. HolickPHD, MD from Boston University OD-0&feature=related Discussion post video

Role in Heart Disease Framingham Heart Study has reinforced the idea that vitamin D is good for the heart (study conducted over a 30 year period) 1,700 middle-aged men chosen initially w/o heart disease. Those with low vitamin D levels were more likely to develop cardiovascular problems Those with normal vitamin D levels were less likely to have heart disease Vitamin D deficiency and risk of cardiovascular disease

Vitamin D & Cancer Breast Prostate/Ovarian ColonPancreas Lung Epidemiologic data suggest that vitamin D status could affect cancer risk National Cancer Institute Fact Sheet (2011). Vitamin D and Cancer Prevention: Strengths and Limits of the Evidence Retrieved from

Conclusion Vitamin D is just not to needed to make bones stronger. It is a hormone that does many things in tissues to different parts of the body. The new ongoing evidence is that vitamin D has numerous benefits. Are you deficient? If you are not sure ask you health provider to check your levels. New research is linking low vitamin D levels with many disease don’t put your health at risk.

RESOURCES Avalier, E., & Delanaye, P., & Chapelle, J., Souberbielle J. (2009). Vitamin D current status and perspectives. Clinical Chemistry & Laboratory Medicine, 47(2), Retrieved from d=abb a78-864e- 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d %3d#db=aph&AN= Clinical Chemistry & Laboratory Medicine d=abb a78-864e- 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d %3d#db=aph&AN= Miller J., & Gallo R. L. (2010). Vitamin D and innate immunity. Dermatologic Therapy, 23, Retrieved from 15&sid=abb a78-864e- 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d %3d#db=aph&AN= Dermatologic Therapy

RESOURCES COUNTINUED National Cancer Institute Fact Sheet (2011). Vitamin D and Cancer Prevention: Strengths and Limits of the Evidence Retrieved form Office of Dietary Supplement National Institutes of Health Fact Sheet: Vitamin Retrieved from Ruxton, C. H., & Derbyshire E. (2009). Health impacts of vitamin D: are we getting enough? Nutrition Bulletin, 34 (issue 2), Retrieved from a78-864e- 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN= Nutrition Bulletinhttp://web.ebscohost.com.lib.kaplan.edu/ehost/detail?vid=15&hid=15&sid=abb a78-864e- 600e6e40a877%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=

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