Bindley Bioscience Center Vision: Nurture interactive communication and interdisciplinary discovery with flexible laboratory project spaces and an open.

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Bindley Bioscience Center Vision: Nurture interactive communication and interdisciplinary discovery with flexible laboratory project spaces and an open environment. Mission: Provide high-level research capabilities with high-end instrumentation and scientific expertise for grant-sponsored projects, centers, and institutions. ■ (765) ■ Bindley Bioscience Center, 1203 W. State St.

Transferring Life-Enhancing Technologies to Society Biomolecular Technologies Computational Life Sciences And Informatics Bio- Nanotechnology Cytomics And Imaging Research Instrumentation Development Biosensors Biomedical Devices New Technologies for Life Sciences Precision Measurements Developing Technologies Impact ● New Companies ● Cancer Diagnostics & Treatment ● Improved Food Supply ● Bio-Fuels ● Bio-Defense ● Infectious Diseases ● Medical Devices ● New Drugs Clinical & Corporate Partners PU Academic Units Discovery Park Centers Core Research Facilities ■ (765) ■ Bindley Bioscience Center, 1203 W. State St. Bindley Bioscience Center

Meeting grand challenges in plant, animal, and human diseases … discovering new technologies to improve health and prevent disease … enhancing early diagnosis … Purdue Analytical Proteomics Team Multidisciplinary collaborative team led by Purdue Bindley Bioscience Center Oncological Sciences Center e-Enterprise Center Cyber Center Purdue Cancer Center Department of Chemistry Indiana University School of Medicine Indiana University (Bloomington) Indiana & Purdue University at Indianapolis (IUPUI) Quadraspec, Inc Safis-Solutions, LLC Hoosier Oncology Group, LLC Monarch Life Sciences (formerly INCAPS) Predictive Physiology and Medicine Project: Clinical Proteomic Technology Assessment for Cancer $7 million grant from National Cancer Institute GOAL: Identify cancer biomarkers for more precise diagnoses and ‎therapies tailored to individuals (personalized medicine). Study proteins/protein components (biomarkers) and their relationships to cancers (specifically, breast and prostate cancers). OUTCOMES: Develop protocols and standardized techniques for all researchers to use to identify specific cancer biomarkers. Create new technologies (systems for highly complex data collection and analysis) to find locations of these biomarkers. ■ (765) ■ Bindley Bioscience Center, 1203 W. State St. Discovery Bindley Bioscience Center

New scientific knowledge about biological systems … multidisciplinary problem-solving experiences for students and faculty … collaborative discovery and innovation student programs 78 Graduate students 9 Undergraduate students 4 High school students 17 Postdoctoral researchers 15 Technical staff scientists 14 BBC staff scientists 4 Visiting scholars 93Purdue faculty members Project: Physiological Bio-Sensing Bindley Bioscience Center; Center for Environment; Birck Nanotechnology Center; Department of Agricultural & Biological Engineering; Weldon School of Biomedical Engineering GOAL: Develop nanoscale biosensors for use in biological applications OUTCOMES: Animal Production: Creating a hand-held device to assess food spoilage by monitoring animal muscle metabolism and breakdown on-site at food production plants. Crop Production: Developing biosensors to measure mineral nutrition and stress physiology of plants to assess growth, metabolism and ion transport. Food Safety: Building biosensor instruments to monitor animal diseases and protect the food supply by detecting foodborne pathogens/toxins. ■ (765) ■ Bindley Bioscience Center, 1203 W. State St. Learning Bindley Bioscience Center

Innovation spun out for commercial development … corporate relationships … external collaborations … new companies formed physics and chemistry combine to create efficient & comprehensive medical testing device Project: BioCD Spinning Disc 21st Century grant from State of Indiana: Bindley Bioscience Center; Birck Nanotechnology Center; Department of Chemistry; Department of Physics GOAL: Create new concepts and tools in laboratory testing and diagnostics OUTCOMES: Develop a spinning disc (laser, detector, reader, spinner, optics, and signal processor) that holds immunoassays and delivers samples by placing tracks of different proteins the disc. Samples are prepared and analyzed with a disc that can perform many different immunoassay measurements per second, producing reliable and effective quantitative analyses. ■ (765) ■ Bindley Bioscience Center, 1203 W. State St. Engagement Bindley Bioscience Center