Key For All Figures CYAN NODE = DBF ORANGE = PRO BROWN = Gov’t YELLOW = Pharma GRAY = VC WHITE = Other Triangle = New Entrant Circle = Incumbent Node size = standardized network degree, constant within figures RED TIE= R&D GREEN = FINANCE BLUE = COMMERCIAL.. MAGENTA = LICENSING Figure 4a Main Component, All Ties Figure 4b Main Component, New Ties

Fig 5a All Ties Fig 5b New Ties

Figure 6a All Ties Figure 6b New Ties

Figure 7a All Ties Figure 7b New Ties