XPC Control Target A/D Converter P MUX Internal Clock Counter 4051 DEMUX Counter Ground 15V Out/In In/Out 4051 MUX Internal Clock Counter 4051 DEMUX Counter Out/In In/Out Ground 15V Motor Controller Voltage Regulator 5, 12, 15, Ground Voltage Regulator 5, 12, 15, Ground 2 Sum. Op-Amplifiers 4 Diff. Op-Amplifiers 2 Sum. Op-Amplifiers 4 Diff. Op-Amplifiers PWM Generator (4 Amplifiers) PWM Generator (4 Amplifiers) LVAD 13 Pins of DV 15

Current pumps on the market use a cable about the size of a coaxial line Available Cables HeartAssist 5™ Pediatric VAD Berlin Heart: INCOR Pump Cable: Silicone

Concept Selection: Signal Transmission System ABCD MICS MHz Bluetooth 2.4 GHzOFDM Over One Wire2 Multiplexed Wires Selection CriteriaWeightRatingNotesWtdRatingNotesWtdRatingNotesWtdRatingNotesWtd Inter-group compatibility Interference 53 Reserved Medical Band151 Unlicensed 2.4GHz Band53 Orthogonal Signals Size 243x5x10 mm836x6x1 mm61 Requires multiple parts2.001 Requires multiple parts2.00 Data Rate 32800kbps633 Mbps94 500kbps plus wire transfer Wire Transfer9.00 Power 34-16dBm121-6 to 4 dBm Wire number reduction 542 wires2042 wires2033 wires wires5.00 Availability of Parts 5124-lead?54Widely202 Requires multiple parts Requires multiple parts20.00 Scope of Project falls within rigorous time line 61 Difficult test platform Unfamiliar topic Reliability 82 Possible loss of signal161 Attenuation of frequency84 Partially wired for control Wired connection32.00 Security 62 Wireless Hacking121Blue Jacking64Wired Signal24.004Wired Signal24.00 Low probability of error 71 Signals sent in separate packets71 73 Signals sent on orthogonal channels Less signal processing28.00 Total Score

4 currents 3 currents 8 signals Motor Pump Interior Electronics (Proposed) 72 bits Differential/Summing Amps 6 Total 12-bit A/D 6 Total Transmitter 6 signals HESA Hall Effect Sensor Array 2 Total AMB Active Magnetic Bearing 2 Total 5V 12V 15V 72 bits 5 bits Wireless Signal Transmission (INT) Receiver Motor Controller PWM Amps 4 Total FPGA For Signal Processing Clock

Motor Control Signal PWM Control Signals (4 or 8) Miniaturization Project Control XPc Target Exterior Electronics (Proposed) Receiver Transmitter 72 bits 5 bits Wireless Signal Transmission (EXT) 6 signals FPGA For Signal Processing Clock 5 bits Requires 2 Wires 15 V Line Ground Line Benefits Eliminates all signal wires Cons 300kHz channels require data in packets Higher bit error rate Limited products available

4 currents 3 currents 8 signals Motor Pump Interior Electronics (Proposed) 72 bits Differential/Summing Amps 6 Total 12-bit A/D 6 Total USB Transceiver 6 signals HESA Hall Effect Sensor Array 2 Total AMB Active Magnetic Bearing 2 Total 5V 12V 15V Multi-Channel Single Wire Signal (INT) Motor Controller PWM Amps 4 Total 1 signal 4 signals 72 bits 5 bits 1-bit Registers

Miniaturization Project Control XPc Target Exterior Electronics (Proposed) USB Transceiver 72 bits Multi-Channel Single Wire Signal (EXT) 5 bits Requires 3 Wires 15 V Line Ground Line 1 Signal Wire Benefits Allows for wider bandwidth Decrease probability of error More control of channel Cons Data rate may be too fast 72 bits 5 bits

Concept Selection - Materials TitaniumSiliconeUHMWPEPolyurethane Selection CriteriaWeightRatingNotesWtdRatingNotesWtdRatingNotesWtdRatingNotesWtd Ease of Fabrication75 Machine Block 358 Room Temp. Cast or Overcoating 565 Machine Block 355Unknown35 FDA Approved for Similar Applications 810 Abiocor control case 802Many165 Prosthetic s 407 Abiocor pump 56 Availability57 Off-the- shelf 355 Special order 259 Off-the- shelf 453 Angioflex, trademarke d 15 High Thermal Conductance 3715 W/m-K W/m-K930.5 W/m-K93 Assumed < 1W/m-K 9 Low Wireless Interference Low Weight634.4 g/cc1891 g/cc g/cc g/cc54 High Durability10 No corrosion 10010Inert1007Inert707Inert70 Total Score Rank

8 currents 3 currents 8 signals Motor Pump Interior Electronics (Proposed) HESA Hall Effect Sensor Array 2 Total AMB Active Magnetic Bearing 2 Total 5V 12V 15V Wire- “Less” Proposal (INT) 3-bit CounterClock 1:5 Multiplexer Wired Signal 6:1 Multiplexer Wired Signal Motor Controller PWM Amps 4 Total Differential/Summing Amps 6 Total

Wired Signal 4 PWM Control Signals 1 Relay Signal Miniaturization Project Control XPc Target Exterior Electronics (Proposed) 1:6 Multiplexer Wire- “Less” Proposal (EXT) Clock3-bit Counter 5:1 Multiplexer Counter Requires 4 Wires 15 V Line Ground Line 2 Signal Wire (1 Clock sync wire) Wired Signal 6 position signals Benefits Cost Effective Wired signal more reliable than wireless Cons Signal only available fraction of time Will require synchronization commands with project 10021