Results and Discussion By: Victor, Eduard and David.

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Presentation transcript:

Results and Discussion By: Victor, Eduard and David

Effect of PEG400 on the Solubility of Benzoic acid Drug solubility is dependent on the volume fraction of the cosolvent The solubility of benzoic acid in aqueous PEG 400 is given by: Cs = 4.4 exp(6.27X)at 37° Cs = 2.6 exp(5.41X)at 20° X is the volume fraction of PEG 400

Effect of Cosolvent on Mass Transfer The solubility of benzoic acid in 40% PEG 400 solution Perfect sink conditions could easily be obtained due to high solubility The concentration solution was observed to increase proportionally with time Increased solubility by cosolvency can ease treatment of experimental data in future studies

Questions and Comments