Metabolism of the whole organism Metabolic profiles of organs Metabolic conditions Blood glucose levels: 90 mg/dL Fuel reserves glucose triacylglycerols.

Slides:



Advertisements
Similar presentations
Long-term Complications of Type 2 Diabetes
Advertisements

Metabolic interrelationship in well fed state  
GLUCAGON AND ADRENALINE ACTION - REGULATION OF METABOLISM
Endocrine Module 1b. Pancreas Gland 6 ” long Horizontal Behind stomach Upper left abdominal quadrant Both endocrine & exocrine functions.
CLINICAL CHEMISTRY (MLT 301) CARBOHYDRATE LECTURE ONE
Gluconeogenesis : An overview
Integration of Metabolism
Integration of Metabolism Jack Blazyk 3/4/04. Well-Fed Conditions.
Integration & Hormone Regulation Integration Branchpoints in metabolism where metabolites can go several directions 1. Glucose 6-phosphate Energy needed.
Chapter 22 Energy balance Metabolism Homeostatic control of metabolism
Metabolism 101 R. Low, 02/10/14 Need to fix text a la part-1
Glucose regulation HBS3A. Blood glucose Sugar travels in the blood as g_________, and is stored in liver and muscle as g__________. Glucose is important.
Integration of Metabolism
Henry Tanner: 1900’s – “Angels and Shepherds”. The Endocrine System Chapter 10:
Hormonal control of circulating nutrients Overview: The need for glucose and nutrient homeostasis Interchange of nutrients / fuel stores Insulin:secretion.
Integration and Regulation of Metabolism. Srere’s ARB Figure There are relatively few metabolites that connect with more than one or two others.
Energy Production II. Protein CHO Fat PyruvateAmino Acids Fatty Acids Acetyl-CoA TCA Cycle and Electron TS ATP produced.
Prentice Hall c2002Chapter 131 Chapter 13 Additional Pathways in Carbohydrate Metabolism Insulin, a 51 amino acid polypeptide that regulates carbohydrate.
Summary of Metabolism. Basic Strategies of Catabolic Metabolism Generate ATP Generate reducing power Generate building blocks for biosynthesis.
Homeostatic Control of Metabolism
PANCREATIC HORMONES Dr. Amel Eassawi 1. OBJECTIVES The student should be able to:  Know the cell types associated with the endocrine pancreas.  Discuss.
Hormones that Affect Blood Sugar Insulin, glucagon, epinephrine, norepinephrine and cortisol.
Gluconeogenesis COURSE TITLE: BIOCHEMISTRY 2 COURSE CODE: BCHT 202 PLACEMENT/YEAR/LEVEL: 2nd Year/Level 4, 2nd Semester M.F.Ullah, Ph.D.
Physiology - Homeostasis
Metabolic effects of Insulin and Glucagon Metabolism in the Well fed state Metabolism in the Starvation and Diabetes Mellitus Integration of Metabolism.
Regulation of carbohydrate metabolism Alice Skoumalová.
Hormonal regulation of carbohydrate metabolism
Integration of Metabolism
Brooks ch 9 p ; –Some small sections already covered Outline Maintenance of Blood Glucose during exercise –Feed forward Control - SNS –Feed.
Endocrine Block Glucose Homeostasis Dr. Usman Ghani.
Integrated Metabolism Biochemistry of the organs –LiverMuscleKidney –HeartBrainAdipose Communication between organs –Cori cycleGlucose-Alanine cycle Metabolic.
PRINCIPLES OF HUMAN PHYSIOLOGY THIRD EDITION Cindy L. Stanfield | William J. Germann PowerPoint ® Lecture Slides prepared by W.H. Preston, College of the.
Integration of Metabolism. Insulin regulation Glucagon regulation Metabolic Regulation in the Fed State Insulin stimulation: Insulin stimulation: Glucose,
Summary of Metabolic Pathways
Energy Requirements Living tissue is maintained by constant expenditure of energy (ATP). ATP is Indirectly generated from –glucose, fatty acids, ketones,
Glucose Homeostasis By Dr. Sumbul Fatma.
Chapter 23 Fatty Acid Metabolism Denniston Topping Caret 6 th Edition Copyright  The McGraw-Hill Companies, Inc. Permission required for reproduction.
NORMAL METABOLISM NORMAL METABOLISM 1. After a meal glucose levels rise, insulin is produced 2. Insulin suppresses glucagon secretion 3. Insulin stimulates.
Ketone body formation and utilisation  Acetoacetate,  -hydroxy butyrate and acetone are collectively called as ketone bodies.  The process of formation.
The Pancreas.
Substrate Breakdown The free Energy of oxidation of a food is the amount of energy liberated by the complete oxidation of the food.
Metabolic interrelationship
Metabolism of Carbohydrates
GLUCAGON. Glucagon: is secreted when “Glucose is GONE” Peptide hormone made of 29 amino acids. MW: 3485 Has several functions that are dramatically opposite.
Selected Hormonal Issues Relating to Exercise and Substrate Use.
Principle Metabolic Pathways During Postabsorptive State Process Diagrams Step-by-Step Copyright © 2007 by John Wiley & Sons, Inc.
The Endocrine System Controlling those Hormones And Maintaining Homeostasis.
Lecture 1 Session Six Control of Energy Metabolism Dr Majid Kadhum.
Organ and metabolism HENDRA WIJAYA.
Endocrine Block Glucose Homeostasis Dr. Usman Ghani.
Integration of Metabolism
Glucagon – A hormone from pancreas Lecture NO:1st BDS
Integration Of Metabolism
The Endocrine Pancreas
Lecture 22 WEB: Go to pollev.com/ucibio TEXT: Text UCIBIO to 37607
Feed-Fast Cycle.
Chapter 24 Metabolic Pathways for Lipids and Amino Acids
Glucose Homeostasis By Dr. Sumbul Fatma.
Metabolism of Protein Amino Acids.
Metabolism of the whole organism Metabolic profiles of organs Metabolic conditions Blood glucose levels: 90 mg/dL Fuel reserves glucose triacylglycerols.
הגוף פועל כיחידת מבנה אחת ומקיים סביבה פנימית יציבה - הומיאוסטזיס
Hormonal Regulation of Carbohydrates
Anatomy & Physiology II
Metabolic Diseases Lesson 2.4
Metabolic Diseases Lesson 2.3
Using Fats and Proteins as Energy Sources
Regulation of carbohydrate metabolism
Hormonal Regulation of Carbohydrates
Glucagon – A hormone from pancreas Lecture NO: 2nd MBBS
The Endocrine Pancreas
Presentation transcript:

Metabolism of the whole organism Metabolic profiles of organs Metabolic conditions Blood glucose levels: 90 mg/dL Fuel reserves glucose triacylglycerols proteins

Metabolic homeostasis

Metabolic profiles

Brain Nervous system: maintain membrane potentials uses glucose (120g/day) 60% of all glucose blood levels of 84.7 = 1mM in brain starvation use ketone bodies Heart : uses fatty acids or ketone bodies

Muscle contraction store glycogen resting use fatty acid oxidation active use glucose starvation muscle broken down to alanine for gluconeogenesis

Adipose Tissue uses fatty acids for energy exports fatty acids glycerol exported out to the liver

Liver & Kidney Liver: provides fuel to other organs gluconeogenesis, maintain blood glucose store glycogen export ketone bodies uses keto acids for fuel Kidney: needs energy for active transport uses FA, KB, glucose, amino acids, gluneogenic tissue

Metabolic conditions Controlled by hormones insulin glucagon epinephrine Normal regulation of blood glucose Insulin secretion

Hormonal control

Hormones

Exercise fuels during different levels of exercise ATP production

Starvation/Fasting Fuel mobilization after 3 day changes long term shifts hormonal changes

Starvation profiles

Fuel Modifications

Liver modifications

Diabetes types of diabetes changes in fuels problems

Insulin deficiency

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.