Tucker et al. 2006. Am J Clinical Nutrition Femur Bone Mineral Density Bell et al. 1977 J of Nutrition High Phosporus Diet Vs. Control Diet Population.

Slides:



Advertisements
Similar presentations
Nutrition for Oral and Dental Health
Advertisements

dr. Susila Sastri M.Biomed Bahagian Biokimia FK-UNAND
Biochemistry of Bone.
بسم الله الرحمن الرحيم.
Ca++ absorbed into blood
Hormonal regulation of calcium and phosphorus homeostasis.
OSTEOPOROSIS An overview of the condition and its treatment
Chapter 19 Bone. A. Endocrine Control of Ca 2+ & PO 4 3-  __________________, 1,25-dihydoxy Vit D, & calcitonin control Ca 2+ and P levels & activities.
MINERALS Damion Francis MSc. TMRI-ERU. Phosphorus 85% of phosphorus is located in bones and teeth Remainder found in muscles, organs, blood, and other.
Meghan Ellis Calcium and Phosphorus Metabolism in Reptiles.
Calcium & phosphor disturbance CKD- MBD Dr. Atapour.
Ca ++ and P i Homeostasis. Ca ++ in the plasma [Ca ++ ] in plasma: 2.5 mM, of which about ½ is bound and thus physiologically inactive. Ratio of free/bound.
Calcium homeostasis. Bone remodeling and repair Continuous remodeling –5 to 7 % of total bone mass per week –Critical for maintenance of proper structure.
Endocrine Regulation of Calcium and Phosphate Metabolism
BIOCHEMISTRY BONE METABOLISM MSK BLOCK SYSTEM Nabil Bashir October 1 st, 2009.
MLAB 2401: Clinical Chemistry Keri Brophy-Martinez Overview: Mineral and Bone Metabolism.
Calcium & Inorganic phosphate. Calcium Physiological function : Bone mineralization Blood coagulation Important in muscle contraction Affecting enzyme.
Diet intestine Stool Calcium pool Kidney Urine Bone mg 825 mg Absorbed 500 mg Secreted 325 mg Formation 280 mg reabsorption 280 mg Reabsorbed
By Dr. Sana Fatima Instructor, Biochemistry Department.
Calcium and its significance in the bone metabolism Romana Šlamberová, MD PhD Department of Normal, Pathological and Clinical Physiology.
DRUGS THAT AFFECT BONE MINERAL HOMEOSTASIS
Calcium & phosphorus.
Pharmacology of drugs used in calcium & vitamin D disorders
Lecture # 12: Calcium homeostasis
Cartilage Structure No nerves or blood vessels Surrounded by perichondrium Matrix Lacunae Chondrocyte.
What is the Bone?. Connective tissue  Organic matrix (cells & proteins)  Inorganic elements (calcium hydroxyapatite)
Parathyroid disorders
Calcium and Phosphorus Metabolism
7-1 Mineral Deposition Mineralization is crystallization process –osteoblasts produce collagen fibers spiraled the length of the osteon –minerals cover.
Bone Tissue A. Physiology: functions of bone B. Anatomy: structure of bone C. Histology of bone D. Bone homeostasis 1. Remodeling 1. Remodeling 2. Bone's.
OUT LINES ■Overview of calcium and phosphate regulation in the extracellular fluid and . plasma ■ Non- Bone physiologic effects of altered calcium and.
Jim, Tyler and Matt. Adult Bones  Adult humans have 206 bones Accounts for ~12-15% of body mass  Some areas have a higher concentration of bones than.
Bone Remodeling Bone remodeling = combination of bone deposition and bone resorption. Deposition = taking minerals (Ca2+, Mg2+, Mn2+, phosphate) from the.
MCAT Session 3. Physics Know all of the equations and units!!!!! Important things to remember from this section  Converging have + focal lengths  Diverging.
( Source, Release & Function ) 1.structure of bone & teeth 6. hormone secretion 5. hormonal actions 2.neurotransmission 4. muscle contraction 3. blood.
By Emily Gilhool. Softening and weakening of the bones Different Types: Hypophosphatemic Rickets Kidney Rickets Nutritional Rickets Rickets.
Copyright © 2010 Pearson Education, Inc. 6-3 Ossification and appositional growth are mechanisms of bone formation and enlargement.
Bone Growth and Fractures
Regulation of C alcium I on L evel in the B lood.
The Parathyroid!!!!!!!!!!! Par Avery MacNeish. Location location location The four small parathyroid glands, about the size of a grain of rice, are hidden.
Concentration of Ions in Solution Remember: concentration IS molarity.
Bone Homeostasis.
Bone Health and the Environment. Bone Functions Calcium HomeostasisCalcium Homeostasis –Calcium “bank” Skeletal IntegritySkeletal Integrity –Muscle –Nerve.
Calcium & Phosphate Metabolism Calcium homeostasis Calcium in blood & cells  or  Ca 2+ — consequences: short term long term Roles of gut, bone, kidney.
Control of Blood Ca. Why is Calcium important? Ca is essential for healthy teeth and skeletal development It is also involved in: Blood clotting (Ca.
Protection: Blood Cell Production: Body Movement: Detoxification: Structural Support: Storage: 1) minerals and 2) lipids Functions of Bone (Osseous.
Chapter 5 Biomineralization
AGENTS FOR BONE AND BONE GROWTH : CALCIUM PREPARATIONS.
AGENTS FOR BONE AND BONE GROWTH : CALCIUM PREPARATIONS.
Bone Metabolism MSS,Fall Nabil Bashir.
Lane: A Case Study in Renal Physiology Melissa Scott Mountain Brook High School 3650 Bethune Drive Birmingham, AL 35223
The Skeletal System v=yENNqRJ2mu0.
HABIBI S.L. TOBING DEPARTMENT OF ORTHOPAEDIC & TRAUMATOLOGY RSUD UNDATA PALU 1.
MLAB 2401: Clinical Chemistry Keri Brophy-Martinez
About 10% of bone is replaced every year in an adult skeleton
Ca++ absorbed into blood
Phosphorus. Phosphorus Learning Objectives Dietary sources Daily Requirements Metabolism Important functions and Deficiency diseases.
Bone Metabolism MSS/Biochemistry, fall-2017
Algorithm of the approach to the diagnosis and treatment of children with fractures due to osteoporosis. BMD, bone mineral density; GC, glucocorticoids;
Chapter 21: Regulation of Calcium and Magnesium
Responses to reduced plasma calcium concentration
Negative feedback regulation of parathyroid hormone (PTH) release
Calcium balance. Dietary intake of calcium averages 1 g/d and is a critical determinant of calcium homeostasis. A small fraction is absorbed in the intestinal.
Chemical Composition of Bone: Organic
Storage as Plant Products, Feeds, Mineral Supplements CROPS
Protein for Healthy Bones
Peripheral Glands.
The ins and outs of phosphate homeostasis
Presentation transcript:

Tucker et al Am J Clinical Nutrition Femur Bone Mineral Density Bell et al J of Nutrition High Phosporus Diet Vs. Control Diet Population Survey (~2,500 people) Questionnaire with X-RAY for BMD

How does high Phosphorus = Lower BMD? Phosphate (PO 4 3-) Ca 2+ or Mg 2+ or Na + & PO 4 3- H + or 2H + & PO % 40% Ca 2+ PTH released Bone breaks down releasing Ca2+ Kidney reabsorbs Ca2+ Intestines uptake more Ca2+ In Plasma

Hydroxyapatite (Ca 5 (PO 4 ) 3 (OH) = Storage of Calcium in Bone Bone Resorption Hydrochloric Acid = Dissolve Mineral Acid Proteases (Enzymes) = Digest Bone Matrix Protiens (Collagen, etc) Bone Structure

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.