Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Slides:



Advertisements
Similar presentations
Martin John Bishop UK HGMP Resource Centre Hinxton Cambridge CB10 1 SB
Advertisements

1 Inference of Regulatory Networks via Systems Genetics Ina Hoeschele.
Cellular Networks.
Characterization of Transcriptional Regulatory Networks controlling plant cell adaptation to environmental stresses.
Keywords: Gene, chromosomes, undifferentiated plasmid, base pairs, Keywords: hydrogen bonds, B2 Topic 1 The Components of Life This topic looks at: DNA.
DNA, AND IN SOME CASES RNA, IS THE PRIMARY SOURCE OF HERITABLE INFORMATION Noneukaryotic Genetic Information.
Differentiation Cell & Molecular Biology. Genetic Control All cells in the body have the same genetic information Not all cells are identical. Cellular.
Chapter 3 Genetics Michael Hoerger. The Basics Nucleus: where most genetic material is stored, contains chromosomes Chromosomes: 46 (23 pairs), carry.
pt 10 pt 15 pt 15 pt 20 pt 20 pt 25 pt 25 pt 5 pt 5 pt 10 pt 10 pt 15 pt 15 pt 20 pt 20 pt 25 pt 25 pt 5 pt 5 pt 10 pt 10 pt 15 pt 15 pt 20 pt.
Bacterial Physiology (Micr430)
Recap Sometimes it is necessary to conduct Bad Science – often the product of having too much information Human Genome Project changed natural scientists.
Regulation of Protein Synthesis
Microbial Genetics (Micr340) Lecture 15 Regulation of Gene Expression.
Gene Expression and Cell Differentiation
[BejeranoFall13/14] 1 MW 12:50-2:05pm in Beckman B302 Profs: Serafim Batzoglou & Gill Bejerano TAs: Harendra Guturu & Panos.
Chromosomes, Gene Expression and Epigenetics
Gene Expression and Cell Differentiation CSCOPE Unit: 08 Lesson: 01.
Marah Dobrenski & Ally Zerfas
Discovering Epigenetics MARY BRUNSON, BROOKLINE HIGH SCHOOL JULIE SNYDER, HUDSON HIGH SCHOOL Massachusetts Institute of Technology Department of Biology.
Natural Selection Variation. Natural Selection Variation Heredity.
Regulating Eukaryotic Gene Expression. Why change gene expression? Different cells need different components Responding to the environment Replacement.
6D Gene expression the process by which the heritable information in a gene, the sequence of DNA base pairs, is made into a functional gene product, such.
Control of Gene Expression Year 13 Biology. Exceptions to the usual Protein Synthesis Some viruses contain RNA and no DNA. RNA is therefore replicated.
Transcriptional - These mechanisms prevent transcription. Posttranscriptional - These mechanisms control or regulate mRNA after it has been produced.
Complexities of Gene Expression Cells have regulated, complex systems –Not all genes are expressed in every cell –Many genes are not expressed all of.
UNIT 3 BIOLOGY Mod. 14: Behavior Genetics—Predicting Individual Differences.
Modelling from Sequence to Gene Regulatory Network to Phenotype.
CS173 Lecture 9: Transcriptional regulation III
DNA Methylation. DNA methylation, the addition of methyl groups to certain bases in DNA, is associated with reduced transcription in some species DNA.
7.2(2) Regulation of Gene Expression. Important Terms Gene expression Gene regulation Epigenetics Genotype Phenotype Lac operon Nucleosomes Methylation.
1/15-19/16 Starter: 1/15 What do you know about genes? 1/19 1/15-19/ Gene Expression and Cell Differentiation Practice/Application/Connection.
Content What is epigenetics?. The Mapping of the Human Genome Project 2000 A working draft but completed in 2003 Only 20,000–25,000 genes! Only 1.5% of.
Gene Regulation.
REVIEW OF MOLECULAR GENETICS DR. EDELBERG. Genes, DNA, & Chromosomes.
Click to continue How do a few genes build a diversity of body parts? There’s more in the genetic toolkit than just genes! Click your forward cursor to.
Regulating Gene Expression WITH OVER GENES IN EVERY CELL, HOW DOES THE CELL KNOW WHAT GENES TO EXPRESS AND WHEN TO EXPRESS THEM?
SC.912.L.16.3 DNA Replication. – During DNA replication, a double-stranded DNA molecule divides into two single strands. New nucleotides bond to each.
Gene Structure and Regulation. Gene Expression The expression of genetic information is one of the fundamental activities of all cells. Instruction stored.
(3) Gene Expression Gene Expression (A) What is Gene Expression?
Chapter 8, part B Microbial Genetics.
Chapter 8, part B Microbial Genetics.
B2 Topic 1 The Components of Life
Ligand- and signal-activated transcription factors (represented by the round and the rectangular symbols, respectively) can bind to the promoter regions.
Regulation of Gene Expression
Welcome to another Bio-Ninja Friday. Quiz today
Chromosomes, Genes & DNA.
Transcription and Gene Regulation
Control of Gene Expression
Regulation of Gene Expression by Eukaryotes
B2 Topic 1 The Components of Life
Gene Regulation.
DNA & protein synthesis Chapter 9
Concept 18.2: Eukaryotic gene expression can be regulated at any stage
Regulation of Protein Synthesis
Eukaryote Regulation and Gene Expression
Control of Gene Expression in Eukaryotic cells
Review Warm-Up What is the Central Dogma?
Epigenetics Heritable alteration of gene expression without a change in nucleotide sequence.
7.2 Transcription & Gene Expression
Genetics and Information
Unit III Information Essential to Life Processes
Non coding DNA Coding Not all DNA codes for a polypeptide to be made May have another useful function Non-coding sequences of DNA e.g. STRs Another example:
Methyl Madness: The Road to the Final Phenotype
Prokaryotic (Bacterial) Gene Regulation
Exploring Epigenetics
GENETIC VARIATION Sources of Variation.
Eukaryotic Gene Regulation
Chapter 8, part B Microbial Genetics.
Nature of Biology 1 Chapter 15 pg
Presentation transcript:

Challenges to the Modern Synthesis Stephen Jay Gould, Nils Eldredge,

DNA

Transcription

Translation Notion of “gene expression”

Question: Why aren’t “identical twins” identical?

Epigenetics From Wikipedia: “Epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence.” Is epigenetics why cloned animals don’t fare well?

Genetic regulation

Genetic Switches (in “non-expressed” regions)

Genetic Regulatory Networks

Random Boolean Networks as models of genetic regulatory networks