 CLINICAL  TEACHING  RESEARCH  ADMINISTRATIVE

Program in Reproductive and Adult Endocrinology Program in Reproductive and Adult Endocrinology Section on Neuroendocrinology Section on Medical Endocrinology Unit on Molecular Hormone Action Section on Reproductive Endocrinology and Infertility Integrative Medicine Group GYN Consult Service

 Unit on Reproductive Regenerative Medicine (URRM) Head, Erin Foran Wolff, M.D. (ACI asst.clin.inv.)  Section On Pediatric Endocrinology Now: UNIT ON MOLECULAR HORMONE ACTION (UMHA) Head, Tomoshige Kino, M.D., Ph.D.  Section On Reproductive Endocrinology Now: SECTION ON CLINICAL AND TRANSLATIONAL ENDOCRINOLOGY (SCTE) Head, Lynnette Nieman, M.D.

DIVISION OF EPIDEMIOLOGY, SERVICES AND PREVENTION RESEARCH (DESPR) NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) NHLBI,NCI,GENOME, etc. REPRODUCTIVE MEDICINE NETWORK (RMN/CREST)

Family Planning Fellowship DESPER Contraceptive Branch PRAE Washington Hospital Center/ Georgetown

Protocol#PITitleStatus 00-CH-0127Abraham, SmitaEvaluation of Patients with Endocrine-Related ConditionsACTIVE ACCRUAL 99-CH-0103Armstrong, AliciaEvaluation of Women with Endocrine and Reproductive-Related Conditions ACTIVE ACCRUAL 12-CH-0015 Armstrong, AliciaEvaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Reduce Bleeding in Premenopausal Women with Abnormal Uterine Bleeding: A Pilot Study ACTIVE ACCRUAL 91-CH-0127Nelson, LawrenceOvarian Follicle Function in Patients with Premature Ovarian FailureACTIVE ACCRUAL 92-CH-0223Nelson, LawrenceAutoimmune Premature Ovarian Failure: A Controlled Trial of Alternate-Day Prednisone Therapy ACTIVE ACCRUAL 00-CH-0189Nelson, LawrenceFSH-Stimulated Inhibin B as a Marker for Early Ovarian InsufficiencyACTIVE ACCRUAL 06-CH-0201Nelson, LawrenceEffect of Transdermal Estradiol Replacement Therapy on Ovulation Rate in Women with Premature Ovarian Failure: A Randomized, Placebo- Controlled Trial ACTIVE ACCRUAL 10-CH-0144Nelson, LawrenceThe Natural History of Reproductive and Overall Health in Women with a Pre-Mutation in the FMR1 Gene: Creation of a Patient Registry ACTIVE ACCRUAL 95-CH-0104Nieman, LynnetteInternal Jugular Vein Sampling for ACTH Levels for the Differential Diagnosis of Cushing Syndrome ACTIVE ACCRUAL 95-CH-0110Nieman, LynnetteEndometrial Mediators of Gonadal Steroid ActionACTIVE ACCRUAL 99-CH-0055Nieman, LynnetteNew Imaging Modalities in the Evaluation of Patients with Ectopic Cushing~s Syndrome ACTIVE ACCRUAL 02-CH-0309Nieman, LynnetteThe Diagnostic Performance of Screening Tests for the Diagnosis of Cushing~s Syndrome ACTIVE ACCRUAL 05-CH-0013Nieman, LynnetteAdrenal Function in Critical IllnessACTIVE ACCRUAL 07-CH-0008Nieman, LynnetteProspective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing~s Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion ACTIVE ACCRUAL 11-CH-0078Nieman, LynnetteEvaluation of cortisol resistance in young endurance-trained and elderly men ACTIVE ACCRUAL

MEDICAL ENDOCRINE CLINIC PATIENTS

Data from AAMC, xx x x x x x x x x x x o o o o o oo o o o O = matriculating x = graduating Percent of Medical Students with a Strong Interest in Research x o x o %

“ From now until the end of the world, we and it shall be remembered. We few, we Band of Brothers. For he who sheds his blood with me shall be my brother. ” - William Shakespeare (King Henry V)

Mission Basic Research Clinical Research Consultative Service (PATIENT CARE) Teaching (Fellowships) Academic Leadership Resource to the world Bench to Bedside

Tuesday May 09, 2006

Geography Mark Hatfield Clinical Research Center Walter Reed Medical Center National Naval Medical Center Uniformed Services University of the Health Sciences Shady Grove Fertility Wayne State University Reprogenetics

The mission of the program for Reproductive and Adult Endocrinology (PRAE) and the Reproductive Biology and Medicine Branch is to carry out clinical, translational and basic research in the areas of reproduction, women's health, adrenal diseases, and neruoendocrine disorders. Maintenance of superior fellowship training programs in reproductive, adult and pediatric endocrinology are paramount, allowing PRAE to achieve a true “bench to bedside” research environment. We service and investigate all aspects of women’s health including abnormal uterine bleeding, endometriosis, reproduction in the patient with cancer infertility, and reproductive endocrine disturbances associated with all acute and chronic diseases. In addition, adrenal disorders, neuroendocrine tumors as well as adrenal and glucocordicoid receptor signaling and physiology are under our umbrella. The biomedical research conducted in PRAE is accomplished through clinical trials, as well as at the cellular, sub-cellular, protein and genomic levels, allowing us to provide outstanding training for the physicians/researchers of tomorrow.