Effects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity Featured Article: Ricardo V. Cohen, M.D., Jose C. Pinheiro, M.D.,

Slides:



Advertisements
Similar presentations
Dr. Monica Nannipieri Dipartimento di Medicina Clinica e Sperimentale Università di Pisa.
Advertisements

THE DIABETES PREVENTION PROGRAM RESEARCH GROUP*
Bariatric Surgery vs. Intensive Medical Therapy in Obese Diabetic Patients: 3-Year Outcome Bariatric Surgery vs. Intensive Medical Therapy in Obese Diabetic.
Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification,Metformin Treatment, or Standard Care in the Diabetes Prevention.
ANALISI COMPARATIVA DELLA GASTRECTOMIA VERTICALE VS BENDAGGIO GASTRICO VS BYPASS GASTRICO IN PAZIENTI CON BMI
Bariatric Surgery in the Transplant Population Guilherme M. Campos, MD, FACS, FASMBS Associate Professor of Surgery University of Wisconsin – Madison
Requested information from seminar March 2011 Co- Morbid conditions Stats and resolutions.
Severe Hypoglycemia and Mortality After Cardiovascular Events for Type 1 Diabetic Patients in Sweden Featured Article: Tom W.C. Lung, Dennis Petrie, William.
Improved Glucose Control With Weight Loss, Lower Insulin Doses, and No Increased Hypoglycemia With Empagliflozin Added to Titrated Multiple Daily Injections.
Why Surgical Treatment of Diabetes May Not be a Good Option McGill First Canadian Summit on Surgery for Type 2 Diabetes Montréal, Québec May 7, 2010 David.
Obesity – Growing epidemic Center for Disease Control and Prevention 2006.
Bariatric Surgery in Obesity and Metabolic Disease Olivier Court MD FRCSC Director, section of Bariatric Surgery McGill University Health Center.
Patient selection and choosing the optional procedure in bariatric surgery A.R khalaj M.D Minimal Invasive Surgery Research Center university of Iran.
MALABSORPTIVE BARIATRIC SURGERY in Low BMI Korean Patients Ji Yeon Park Soonchunhyang University Seoul Hospital, Korea.
E. McLaughlin, P. D. Chakravarty, D. Whittaker, E. Cowan, K. Xu, E. Byrne, D.M. Bruce, J. A. Ford University of Aberdeen.
Safety of Ambulatory Bariatric Surgery Senapati PS, Menon A, Al-Rashedy M, Thawdar P, Akhtar K, Ammori BJ Department of Obesity and Metabolic Surgery Salford.
Metabolic Surgery for Type 2 Diabetes
Complications Associated with Laparoscopic Adjustable Gastric Banding for Morbid Obesity Dr. Mojtaba Hashemzadeh Dr. Leila Zahedi-Shoolami Dr. Mahmoud.
An Automated Internet Behavioral Weight-Loss Program by Physician Referral: A Randomized Controlled Trial Featured Article: J. Graham Thomas, Tricia M.
Post-Surgical Care of the Bariatric Patient
1 Journal Club Alcohol, Other Drugs, and Health: Current Evidence July–August 2012.
Fight obesity with effective and guaranteed tools t Haitham Al-Khayat, MD Consultant general and bariatric surgeon New Dar Al-Shifa hospital.
Metabolic Surgery Abul Fazal Ali Khan Professor of Surgery Allama Iqbal Medical College Lahore.
Jaime Ponce MD, FACS, FASMBS Director of Bariatric Surgery Hamilton Medical Center Dalton Georgia USA LAGB Weight Loss and Diabetes 2010 Minimally Invasive.
The Case Against Bariatric Surgery Centers of Excellence Edward H. Livingston, MD, FACS, AGAF Professor and Chairman, Division of Gastrointestinal Surgery.
MISS Journal Club 2012 Metabolic Surgery & Emerging Technologies Goal: To review 5 important and clinically relevant papers from 2011, on Metabolic Surgery.
Ali Ardestani, David Rhoads, Ali Tavakkoli
Obesity Surgery : Is it only for losing weight ? Joint Hospital Surgical Grand Round Simon Chu Prince of Wales Hospital.
Bariatric Surgery and Metabolism Goal: to review 4 important and clinically relevant papers from 2010 on Bariatric Surgery and Metabolism 10/10/20151.
BPD-DS & Sleeve Gastrectomy Journal Club Goal: To review 4 important and clinically relevant papers from 2010 on BPD-DS or Sleeve Gastrectomy 4 papers;
Independent Association Between Obstructive Sleep Apnea Severity and Glycated Hemoglobin in Adults Without Diabetes Featured Article: Pascaline Priou,
Antibiotics Versus Conservative Surgery for Treating Diabetic Foot Osteomyelitis: A Randomized Comparative Trial Featured Article: José Luis Lázaro-Martínez,
CDC’s Division of Diabetes Translation. National Diabetes Surveillance System available at Obesity (BMI≥30 kg/m.
Gastric Banding Journal Club Goal: to review 4 important and clinically relevant papers from 2010 on Adjustable Gastric Banding 4 papers x 4 min each =
Impact of Socioeconomic Status on Cardiovascular Disease and Mortality in 24,947 Individuals With Type 1 Diabetes Featured Article: Araz Rawshani, Ann-Marie.
Metabolic Effects of Bariatric Surgery
Aspects of Exercise before or after Bariatric Surgery Pouwels, S; Wit, M; Teijink, JA; Nienhuijs, SW Monday 13th of July15:10-15:40.
The Hyperglycemia and Adverse Pregnancy Outcome Study
Early Loss of the Glucagon Response to Hypoglycemia in Adolescents With Type 1 Diabetes Featured Article: Aris Siafarikas, F.R.A.C.P., M.D., Robert J.
Safety and Efficacy of Sitagliptin Therapy for the Inpatient Management of General Medicine and Surgery Patients With Type 2 Diabetes A pilot, randomized,
Long-Term Complications and Mortality in Young-Onset Diabetes Type 2 diabetes is more hazardous and lethal than type 1 diabetes Featured Article: Maria.
Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial Featured Article: TODAY Study Group* Diabetes Care Volume 36:
Gastric Bypass: Continuing Issues Walter J. Pories, MD, FACS Professor of Surgery, Biochemistry, Sport and Exercise Science Brody School of Medicine East.
Evaluation of Current Eligibility Criteria for Bariatric Surgery Diabetes prevention and risk factor changes in the Swedish Obese Subjects (SOS) study.
Clinical and Economic Benefits Associated With the Achievement of Both HbA1c and LDL Cholesterol Goals in Veterans With Type 2 Diabetes Featured Article:
Treatment of GERD in Obese Patients David W Rattner, MD.
Short- and Long-Term Mortality After Myocardial Infarction in Patients With and Without Diabetes Featured Article: Sjoerd T. Nauta, M.S.C., Jaap W. Deckers,
The Effect of Obesity on Direct Medical Costs in Total Knee Arthroplasty by Hilal Maradit Kremers, Sue L. Visscher, Walter K. Kremers, James M. Naessens,
Ricardo V. Cohen MD, Jose C. Pinheiro, MD, Carlos A. Schiavon, MD Joao E. Salles, MD, Bernardo L. Wajchenberg, MD, David E. Cummings, MD Effects of Gastric.
Long-term outcomes of bariatric procedures: sleeve gastrectomy, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch D Kröll, Y.
Bariatric Surgery for T2DM The STAMPEDE Trial. A.R. BMI 36.5 T2DM diagnosed age 24 On Metformin, glyburide  insulin Parents with T2DM, father on dialysis.
Philip R. Schauer, M.D., Deepak L. Bhatt, M.D., M.P.H., John P. Kirwan, Ph.D., Kathy Wolski, M.P.H., Stacy A. Brethauer, M.D., Sankar D. Navaneethan, M.D.,
Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine A 24-Week,
Castellani RL, Toppino M, Favretto F, Camoglio FS, Zampieri N
Dr. Mojtaba Hashemzadeh Dr. Leila Zahedi-Shoolami
Hippocrates Prize Prof A. Kokkinos (Greece).
The Cardiovascular Pipeline
Wilson MSJ, Alhamdani A, Mahawar K, Boyle M
NCEPOD Launch Too Lean a Service
Patient Outcomes in Bariatric Surgery: Bridging the Divide to Postoperative Success.
Key clinical efficacy outcomes for (A) hemoglobin A1c (HbA1c), (B) weight change. Key clinical efficacy outcomes for (A) hemoglobin A1c (HbA1c), (B) weight.
Looking Beyond Glucose Control: Multifactorial Management of Type 2 Diabetes.
Risk of low birth weight and micronutrient deficiencies in neonates from mothers after gastric bypass: a case control study  Geraldine Gascoin, M.D.,
Study Hypothesis Does Roux-en-Y gastric bypass (RYGB) surgery result in improved morbidity when severely obese non-surgical groups (population-based and.
Section overview: Cardiometabolic risk reduction
Anna Cowell James O’Connell Aintree Weight Management Team
Total plasma BCAA (A) and C3 and C5 acylcarnitine (AC) (B) concentrations in the basal state and during insulin infusion in obese subjects before and after.
Relationship between changes in mean fat cell volume and insulin sensitivity (M values) after gastric bypass of obese women. Relationship between changes.
Outcomes of Roux-en-Y gastric bypass versus sleeve gastrectomy in super-super- obese patients (BMI ≥60 kg/m2): 6-year follow-up at a single university 
Presentation transcript:

Effects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity Featured Article: Ricardo V. Cohen, M.D., Jose C. Pinheiro, M.D., Carlos A. Schiavon, M.D., João E. Salles, M.D., Bernardo L. Wajchenberg, M.D., David E. Cummings, M.D. Diabetes Care Volume 35: July, 2012

Study Objectives Cohen R et al. Diabetes Care 2012;35: Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes in severely obese patients through mechanisms beyond just weight loss, and it may benefit less obese diabetic patients Study determined the long-term impact of RYGB on patients with diabetes and only class I obesity (BMI 30–35 kg/m 2 )

Study Design & Methods Sixty-six consecutively selected diabetic patients with BMI 30–35 kg/m 2 underwent RYGB in a tertiary-care hospital and were prospectively studied for up to 6 years (median 5 years [range 1–6]), with 100% follow-up Main outcome measures were safety and the percentage of patients experiencing diabetes remission (HbA1c < 6.5% without diabetes medication) Cohen R et al. Diabetes Care 2012;35:

Conclusions Largest, longest-term study to date examining RYGB for diabetic patients without severe obesity RYGB safely and effectively ameliorated diabetes and associated comorbidities, reducing cardiovascular risk, in patients with a BMI of only 30–35 kg/m 2 Cohen R et al. Diabetes Care 2012;35: