Extensions of Mendelian Analysis

Slides:



Advertisements
Similar presentations
Mendelian Genetics (The Inheritance of Many Traits)
Advertisements

Chapter 14~ Mendel & The Gene Idea
16 and 18 March, 2004 Chapter 14 From Gene to Phenotype Dominance, epistasis, gene interaction.
CO 03 Extension to Mendel: complexities in relating genotype to phenotype.
Autosomal dominant inheritance All affected individuals should have an affected parent Both sexes should be equally affected Roughly 50% of the offspring.
Copyright © 2009 Pearson Education, Inc. Extensions of Mendelian Genetics Chapter 4 Lecture Concepts of Genetics Tenth Edition.
Modes of Inheritance Jonathan Wolfe Wolfson House, room 109
Lecture #6 – Bombay Phenotype & Epistasis
Chapter 4: Modification of Mendelian Ratios
Fig. 6-1 Chapter 6: from gene to phenotype. Using Neurospora, Beadle & Tatum showed that genes encode enzymes and that most enzymes work in biochemical.
Animations 4.1 (black) 1 AA : 2 Aa : 1 aa complete dom/rec dom dom rec incomplete dominance dom blend dom-rec rec codominant dom1 dom1+ dom2.
Chapter 4: Modification of Mendelian Ratios Allele *Wild-type allele *Mutant allele Conventional symbols for alleles: recessive allele - initial letter.
Dihybrid (or greater) Crosses: Review For either genotype or phenotype, the expected outcomes of a particular cross can be calculated by multiplying the.
Genetics Part II Chapter 7.
KEY CONCEPT Phenotype is affected by many different factors.
C. Beyond Dominant and Recessive Alleles 1. Incomplete Dominance a. One allele is not completely dominant over another b. The heterozygous phenotype is.
RR WW RW With incomplete dominance, neither allele is completely dominant nor completely recessive. --> Heterozygous phenotype is an ______________.
Chapter 5 Outline 5.1 Dominance Is Interaction between Genes at the Same Locus, Penetrance and Expressivity Describe How Genes Are Expressed as.
Chapter 14 – Mendel and the Gene Idea. Gregor Mendel Mid 19 th century Austrian monk.
LECTURE CONNECTIONS 5 | Extensions and Modifications of Basic © 2009 W. H. Freeman and Company Principles.
C-13 Part II Non-Mendelian inheritance Most phenotypes reflect the influences of several to many genes and by the environment.
7.2 Complex Patterns of Inheritance KEY CONCEPT Phenotype is affected by many different factors.
RECAP Manx cat Mm MMMMm m mm Manx Death Normal. PLEIOTROPY Is multiple effects of a single gene on the phenotype Occurs for several reasons – suppression.
Mendelian Genetics Ch 14.
Chapter 4: Modification of Mendelian Ratios Allele *Wild-type allele *Mutant allele Conventional symbols for alleles: recessive allele- initial letter.
How do we account for genetic variation? *Independent assortment *Crossing over *Random fertilization Independent Assortment: Cross over:
Blending Theory of Inheritance: Parental traits are “mixed” in the offspring Does NOT explain: how population did not reach a uniform appearance how some.
Extensions to Mendel: Complexities in Relating Genotype to Phenotype.
Chapter 4: Modification of Mendelian Ratios Allele *Wild-type allele *Mutant allele Conventional symbols for alleles: recessive allele- initial letter.
Incomplete Dominance Neither allele is dominant over the other
Types of Dominance Punnett Squares Cont. Pp , 244
Incomplete Dominance and Codominance
Chapter 14: Mendel & The Gene Idea
( Modification of Mendelian ratios )
GENE GENE TNTERACTION.
Monohybrid Crosses.
Mendel & the Gene Idea.
Incomplete Dominance:
Incomplete Dominance and Codominance
KEY CONCEPT Phenotype is affected by many different factors.
Incomplete Dominance & Codominance
KEY CONCEPT Phenotype is affected by many different factors.
KEY CONCEPT Phenotype is affected by many different factors.
KEY CONCEPT Phenotype is affected by many different factors.
Incomplete Dominance and Codominant Traits
Genetics: Mendel & The Gene Idea.
KEY CONCEPT Phenotype is affected by many different factors.
Genetics definitions Label each chromosome pair as homozygous dominant, homozygous recessive, or heterozygous with definitions Label dominant.
Non-Mendelian Genetics
KEY CONCEPT Phenotype is affected by many different factors.
Incomplete Dominance Codominance Multiple Alleles
Incomplete Dominance Incomplete Dominance: The heterozygous genotype produces a phenoytype that falls in between the dominant trait and the recessive trait.
Dominant allele with recessive lethality (black) Dominant allele with recessive lethality.
Date: Feb 10, 2015 Page:Table of Contents p. 1. W. O. D: Last 5 pages
Patterns of Inheritance
Other Patterns of Inheritance
Review Brown eyes are dominant to blue eyes. A purebred brown eyed person has children with a blue eyed person. What are the genotypic and phenotypic.
Lecture # 6 Date _________
KEY CONCEPT Phenotype is affected by many different factors.
Incomplete Dominance Incomplete Dominance: The heterozygous genotype produces a phenotype that falls in between the dominant trait and the recessive trait.
Complete, Incomplete & Co-Dominance
Incomplete Dominance Codominance Multiple Alleles
Incomplete Dominance Codominance Multiple Alleles
KEY CONCEPT Phenotype is affected by many different factors.
Dominance and Multiple Alleles
KEY CONCEPT Phenotype is affected by many different factors.
Types of Inheritances I Pp , 244
KEY CONCEPT Phenotype is affected by many different factors.
KEY CONCEPT Phenotype is affected by many different factors.
Looking at incomplete and codominance
Presentation transcript:

Extensions of Mendelian Analysis Modifications of Mendelian Ratios Single Gene modifications Two gene pair modifications: modified 9:3:3:1 ratios Modification of Expression

Single Gene modifications Incomplete dominance (partial dominance) Multiple alleles Lethal alleles

Incomplete dominance (partial dominance) Expression of a heterozygous phenotype that is distinct from and usually intermediate to either homozygous phenotype

Incomplete dominance (partial dominance) Tay Sachs and Sickle Cell Anemia Heterozygous are intermediate at the biochemical level.

Multiple Alleles &Co-Dominance

Bombay phenotype H allele affected Recessive epistasis Show O phenotype Genotype variable

Lethal alleles Yellow dominant to Agouti coat color No purebred yellow Deletion mutation Recessive for lethality

Two gene pair modifications: modified 9:3:3:1 ratios Epistasis Suppression Complementary gene action

Recessive Epistasis

Dominant Epistasis

Suppression

Complementary gene action

Complementary gene action

Modification of Expression Pleiotropic effects Penetrance and Expressivity

Pleiotropic effects

Penetrance No expression

Expressivity

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.