FLOCHART Principle of flowcharts composition

A flowchart is a type of diagram that represents an algorithm or process, showing the steps as boxes of various kinds, and their order by connecting these with arrows.

This diagrammatic representation can give a step- by-step solution to a given problem.

Data flows are not typically represented in a flowchart, in contrast with data flow diagrams; rather, they are implied by the sequencing of operations.

Flowcharts are used in analyzing, designing, documenting or managing a process or program in various fields.

Flowcharts are used in designing and documenting complex processes. Like other types of diagram, they help visualize what is going on and thereby help the viewer to understand a process, and perhaps also find flaws.

The two most common types of boxes in a flowchart are: a processing step, usually called activity, and denoted as a rectangular box; a decision, usually denoted as a diamond.

Common alternate names include: flowchart, process flowchart, functional flowchart, process map, process chart, functional process chart, business process model, process model, process flow diagram, work flow diagram, business flow diagram.

Technological flowchart is the visual display of dosage production. Technological flowchart (Process flowsheet) - a sequence and description of all stages in manufacturing of a product.

Arrows Showing "flow of control". An arrow coming from one symbol and ending at another symbol represents that control passes to the symbol the arrow points to.

Generic processing steps Represented as rectangles.

Direct compression - a method obtaining of tablets without granulation. Stages of Direct compression: 1. Mixing active and auxiliaries substances 2. Compressing tablets

Stages of wet granulation: 1. Mixing components (drum mixer); 2. Granulation: Adding solutions of binders (moistening of powder); Granulation of the moistened mass – obtaining of wet granules; Drying of wet granules; Granulation of the dried granules; 3. Powdering (dusting) of dry granules 4. Compressing tablets and dust control (tablets machine);

Stages of Dry granulation: 1. Mixing components (drum mixer); 2. Granulation: Adding solutions of binders (moistening of powder); Adding solutions of binders (moistening of powder); Drying of wet granules; Drying of wet granules; Granulation of the dried granules; Granulation of the dried granules; 3. Powdering ((dusting)of dry granules 4. Compressing tablets and dust control (tablets machine).

Stages of Briquetting (type of dry granulation) : 1. Mixing components; 2. Compressing of briquettes; 3. Milling of briquettes to granules ; 4. Separation granules on the fractions with certain size; 5. Compressing tablets and dust control ;

Granulation in dragee pan Stages: 1. Mixing components 1. Mixing components (medicinal and auxiliary); 2. Moistening of powder; 3. Drying wet binder and formation granules; 4. Powdering granules; 5. Compression tablets and dust control; 6. Packing.

Granulation by spray drying 1. Preparation suspension of the auxiliary and sometimes of medicines substances; 2. Serving suspension throw nozzles in camera of dryer and formation granules under hire temperature; 3. Fractionation granules; 4. Mixing granules and medicines substances; 5. Compression tablets and dust control.

Stages of the granulation in the fluidized layer 1. Mixing components (medicinal and auxiliary); Moistening of powder; Moistening of powder; Drying and formation of granules; Drying and formation of granules; Powdering of granules; Powdering of granules; Compression tablets and dust control; Compression tablets and dust control; Packing. Packing.

Stage of capsules production: 1. Preparing of gelatin solutions. 2. Preparing of gelatin shells. 3. Hard-gelatin capsule filling. 4. Packing and labeling. 1. Preparing of gelatin solutions. 2. Preparing and filling of soft-gelatin capsules. 3. Packing and labeling.

Obtaining of gelatin solutions with stage of swelling 1. Swelling of gelatin in cold water ( °C, hours). 2. Dissolving of gelatin. 3. Adding preservatives, plasticizers and others excipients. 4. Remove of air bubbles from the solution of the gelatin by the vacuum. 5. Stabilization of solution of the gelatin (45-60 °C).

Obtaining of gelatin solutions without stage of swelling 1. Heating of purified water (70-75 °C). 2. Dissolution of preservatives, plasticizers and others excipients in the water. 3. Dissolution of the gelatin. 4. Remove of air bubbles from the solution of the gelatin by a vacuum. 5. Stabilization of the solution of the gelatin (45-60 °C).