Mutations. Definition mutation A mutation is a change in an organism’s DNA – Silent mutations are changes that do not result in a change to the organisms.

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Presentation transcript:

Mutations

Definition mutation A mutation is a change in an organism’s DNA – Silent mutations are changes that do not result in a change to the organisms phenotype – Mutations that occur in germ cells (sperm, eggs) are passed on to offspring – Mutations in somatic (body) cells may be harmless, or may result in disease such as cancer

Chromosomal Mutations

A Point Mutation Resulting in Nonsense

A Point Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d m o g b i t t h e t a n c a t This point mutation changes the meaning, resulting in nonsense

A Point Mutation Resulting in Missense

A Point Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d h o g b i t t h e t a n c a t This point mutation changes the meaning, resulting in missense

An Insertion Mutation in a Gene

An Insertion Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d r d o g b i t t h e t a n c a This insertion mutation changes the reading frame

A Deletion Mutation in a Gene

An Deletion Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d o g b i t t h e t a n c a t _ This deletion mutation changes the reading frame

A Frameshift Mutation