Gout Review 2009 Pathophysiology, Diagnosis, and Treatment Robert E. Hiltz, MD Rheumatology Group Health Associates Cincinnati, Ohio.

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Presentation transcript:

Gout Review 2009 Pathophysiology, Diagnosis, and Treatment Robert E. Hiltz, MD Rheumatology Group Health Associates Cincinnati, Ohio

Choi, H. K. et. al. Ann Intern Med 2005;143: Mechanisms of monosodium urate crystal formation and induction of crystal- induced inflammation

TXF-00099

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: foot

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: knee (arthroscopy)

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi, ear

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi of the pinna, ear

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: olecranon bursitis

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: hands

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi, hand

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophus, hand

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophi, hands

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: tophus, finger

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout of distal interphalangeal joints simulating osteoarthritis

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: hand (radiograph)

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: hand (radiograph)

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Choi, H. K. et. al. Ann Intern Med 2005;143: Putative mechanisms for chronic monosodium urate-induced inflammation and cartilage and bone destruction Modified from IL-1

Choi, H. K. et. al. Ann Intern Med 2005;143: Putative mechanisms for chronic monosodium urate-induced inflammation and cartilage and bone destruction Modified from IL-1

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: foot (radiograph)

Copyright © American College of Rheumatology Slide Collection. All rights reserved. Gout: advanced disease, foot (radiograph)