Radiation Safety Chapter 9 Bushong.

Slides:



Advertisements
Similar presentations
Radiation safety in CT.
Advertisements

PHARMACOKINETIC.
Radiation safety in CT.
Venipuncture and Pharmacology for Radiologic Technologists RTEC 93 10:30am- 12:40pm Monday 10:30am- 12:40pm Monday 1pm – 3:10pm Wednesday.
Computed Tomography Physics, Instrumentation, and Imaging
December 10, 2004by Debbie Miller1 Fuchs’s Radiographic Principles THE 15 PERCENT RULE.
Image Artifacts Chapter 8 Bushong.
Spiral CT Bushong Chapter 5.
Seeram Chapter 13: Single Slice Spiral - Helical CT
RAD309 Patient Dose.
CVT 102.  Time  Distance  Shielding.
Radiation Exposure, Dose and Relative Biological Effectiveness in Medicine Background Image:
Special Imaging Techniques Chapter 6 Bushong. Dynamic Computed Tomography (DCT) Dynamic scanning implies 15 or more scans in rapid sequence within one.
IV Flow Rates –BASED ON BODY WEIGHT
Calculating Heparin Bolus Dosage and IV Rate
Pharmacokinetics Questions
Chapter 2 Stewart C. Bushong
One-compartment open model: Intravenous bolus administration
By: Assoc. Prof Dr. Mohammed Ahmed Ali. MR Contrast Media MRI contrast agents contain paramagnetic or super paramagnetic metal ions which affect the MR.
RADIATION SAFETY Phil Facey Lead Superintendent Radiographer
LEC (2) Design/layout by E Bashir, CAMS, King Saud University, 2008.
Laplace transformation
Practical Pharmacokinetics
Dose Adjustment in Renal and Hepatic Disease
Safety and risk. بسم الله الرحمن الرحيم Objective Objective 1-Radiation safety 1-Radiation safety 2-Contrast agent 2-Contrast agent.
Measures to Support Safety in Dental Radiography Pamela Alston, DDS, MPP Lead Oral Health Specialist.
Revision Dr Mohamed El Safwany, MD.. Liver CT Blood circulation in the liver comprises two major components: the hepatic artery and the portal vein. After.
Quantitative Pharmacokinetics
PHARMACOKINETICS 1. Fate of drugs in the body 1.1 absorption
Biotransformation and metabolism
CT physics and instrumentation
Computed Tomography Q & A
HEALTH PHYSICS TERMS l RAD (Gy) l mRad l R l mR l Rem l ALARA l NCRP.
IAEA International Atomic Energy Agency Optimization of Protection in Computed Tomography (CT)-What can radiographers do? IAEA Regional Training Course.
Historical Review and Modalities in Diagnostics
Drug Administration Pharmacokinetic Phase (Time course of ADME processes) Absorption Distribution Pharmaceutical Phase Disintegration of the Dosage Form.
Core Concepts in Pharmacology Chapter 5 Pharmacokinetics.
Attenuation As x-rays pays through matter, the exit beam will contain less photons than the entrance beam. This reduction in the quantity of photons is.
Part No...., Module No....Lesson No
1. Fate of drugs in the body 1.1 absorption 1.2 distribution - volume of distribution 1.3 elimination - clearance 2. The half-life and its uses 3. Repeated.
Continuous intravenous infusion (one-compartment model)
Quality Assurance.
BIOPHARMACEUTICS.
Radiation Protection Procedures
Principles of pharmacokinetics Prof. Kršiak Department of Pharmacology, Third Faculty of Medicine, Charles University in Prague Cycle II, Subject: General.
TDM Therapeutic Drug Monitoring
Quality Control Bushong Chapter 10.
What are the dose quantities in CT ? IAEA/RCA Kampala Kampala.
DEFINITIONS T1/2 & Tmax Cmax AUC 1st order kinetics
Principles of Drug Action
Interaction of x-ray photons (and gamma ray photons) with matter.
Computed Tomography Computed Tomography is the most significant development in radiology in the past 40 years. MRI and Ultrasound are also significant.
CONTRAST STUDIES. 1. Intravenous 2. Intrarterial 3. Oral 4. Intrathecal 5. Intraarticular.
Pharmacokinetics 3rd Lecture
MULTIPLE DOSAGE REGIMEN
Compartmental Models and Volume of Distribution
Pharmacokienetic Principles (2): Distribution of Drugs
Nicole Jensen, RN, Meganne Janssen, MSN, MHA, RN 
Computed Tomography Basics
Radiation Protection RTMR 284 CHAPTER 21.
The aminoglycoside antibiotics
Pharmacokinetic Modeling (describing what happens)
Pharmacokinetics Tutoring
Quantitative Pharmacokinetics
Strategies for Reducing Radiation Exposure From Multidetector Computed Tomography in the Acute Care Setting  Aaron Sodickson, MD, PhD  Canadian Association.
Radiation Protection Procedures
Classification, Chemistry & Pharmacology of Contrast Agents
Occupational Radiation Dose Management
Medication Administration for Pediatrics
The viscosity can be reduced by lowering the concentration of the contrast medium, but reducing the iodine concentration in this way may also result in.
Presentation transcript:

Radiation Safety Chapter 9 Bushong

Patient Radiation Dose Generally, patient radiation dose is higher during computed tomography (CT) than during radiography or fluoroscopy Patient radiation dose during CT is approximately 5000 mrad per examination Patient radiation dose during radiography is approximately 4000 mrad/min with doses ranging from 1000 – 10,000 mrad per examination

Patient Radiation Dose Patient radiation dose during spiral CT is inversely proportional to pitch Patient radiation dose during CT is nearly uniform throughout the body, while that from radiography or fluoroscopy is maximum at the entrance skin For a given collimation during spiral CT, higher pitch results in lower patient radiation dose

Patient Radiation Dose Patient radiation dose is often less in spiral CT because overlapping images can be reconstructed without overlapping scans Patient radiation dose during CT is higher with thinner slices or overlapping slices As with any x-ray imaging, patient dose can be reduced at the expense of image noise

Patient Radiation Dose When patient dose is specified for a CT examination, it is usually an average value of a dose distribution The dose profile is most helpful in identifying patient dose Patient dose in CT is measured with a pencil ionization chamber Patient dose in CT is described by the CT dose index (CTDI)

Radiation Dose The CTDI is equal to the multiple scan average dose (MSAD) if the slice thickness (ST) is equal to the couch incrementation (CT) If the ST does not equal CI, MSAD is equal to the CTDI multiplied by CI

Personnel Radiation Exposure Area radiation exposure is figure-eight shaped Lowest area radiation exposures are in the plane of the gantry and outside the patient aperature Highest are radiation exposure is near the patient and is due to scatter radiation produced in the patient

Personnel Radiation Exposure Area radiation exposure is approximately 1 mR/scan at 1 m from the scan plane It is permissible for a CT technologist to remain in the room during examination but protective apparel must be worn When a technologist is in the room during examination, the radiation monitor should be positioned at collar level above the protective apron

Personnel Radiation Exposure As Low As Reasonably Achievable (ALARA) Cardinal principles Time Distance Shielding

Contrast Media The number of particles of contrast media (solute) per kg of water (solvent) is osmolity ***I haven’t exactly heard of osmolity, it appears in several journal articles but is a rather difficult word for which to find an exact definition.**** Osmolality is defined as the number of particles in solution, or the number of milliosmoles per kilogram, or the concentration of molecules per weight of water Osmolarity is defined as the number of milliosmoles per liter of solution, or the concentration of molecules per volume of solution *** Since Bushong seems to be referring to particles per kg I will use the term osmolality rather than osmolity***

Contrast Media High osmolar contrast media (HOCM) is the conventional “ionic” contrast media Blood has an osmolality of approximately 300 mOsm/kg water HOCM has 4 to 8 times the osmolality of blood (1200 to 2500 mOsm/kg) HOCM is considered to be more toxic than low osmolar contrast media (LOCM)

Contrast Media LOCM is “non-ionic” contrast media LOCM contrast media has 2 to 3 times the osmolality of blood (600 – 800 mOsm/kg water) Contrast media has a biologic half-life of 10 to 90 minutes Ninety percent of contrast media is excreted within 24 hours

Contrast Media Peak urine concentration occurs approximately 2 hours following administration Contrast media can be excreted through liver but is primarily excreted through kidneys Patients with poor renal function have increased excretion of contrast media through gallbladder and small intestine

Contrast Media Contrast media does not change when excreted in mother’s milk Contrast media enhance contrast resolution by increased photoelectric effect Atomic number for iodine is 53 Degree of contrast enhancement is directly related to iodine concentration Following intravenous injection, peak iodine blood concentration occurs within 2 min

Contrast Media Following IV injection, the vascular compartment biologic half-life for iodinated contrast is approximately 20 minutes Iodinated contrast media is transferred from the vascular to the extra vascular compartment in about 10 minutes for equilibrium followed by an exponential decrease in both

Contrast Media Renal accumulation occurs in approximately 1 minute with maximum contrast occurring in 5 to 15 minutes Severely impaired renal function results in prolonged plasma levels and poor contrast resolution Contrast media should be warmed to body temperature before administration

Contrast Media Contrast media may be administered by bolus injection or rapid infusion Adult dosage is 150ml to 250ml ***At my institution the adult dosage is between 100ml to 150ml but never above 150ml Omnipaque*** Child dosage is 1 ml/kg to 3 ml/kg ***my institution uses 1 ml/lbs***

Contrast Media Less contrast is required for spiral CT An over dosage may be life threatening by compromising the cardiovascular or pulmonary systems Contrast media is dialyzable since it does not bind to plasma or serum protein Reaction to contrast media is unpredictable. Personnel must be trained to recognize contrast media reaction and respond appropriately

Contrast Media Fatal contrast reactions reportedly occur from 6 to 100/M