Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients Felipe de Sousa E Melo, Selcuk Colak,

Slides:



Advertisements
Similar presentations
How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni
Advertisements

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion Tiago C. Luis, Brigitta A.E. Naber, Paul P.C. Roozen, Martijn H. Brugman,
The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans Frank L. van de Veerdonk, Renoud J. Marijnissen, Bart Jan Kullberg, Hans.
Mechanism of Homology Recognition in DNA Recombination from Dual-Molecule Experiments Iwijn De Vlaminck, Marijn T.J. van Loenhout, Ludovit Zweifel, Johan.
Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate Laurens G. van der Flier, Marielle E. van Gijn, Pantelis Hatzis, Pekka Kujala,
High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene Alejandra.
The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells Marc van de Wetering, Elena Sancho, Cornelis Verweij, Wim de.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
The Neurobiology of Decision: Consensus and Controversy Joseph W. Kable, Paul W. Glimcher Neuron Volume 63, Issue 6, Pages (September 2009) DOI:
Lessons from Hereditary Colorectal Cancer
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.
Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.
Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Prediction and Testing of Novel Transcriptional Networks Regulating Embryonic Stem Cell Self-Renewal and Commitment Emily Walker, Minako Ohishi, Ryan E.
C/EBPβ at the core of the TGFβ cytostatic response and its evasion in metastatic breast cancer cells Roger R. Gomis, Claudio Alarcón, Cristina Nadal, Catherine.
The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.
Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)
Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics Carlos L. Arteaga, Jeffrey A. Engelman Cancer Cell Volume.
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia Tim C.P. Somervaille, Michael L. Cleary Cancer Cell.
The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.
Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.
Wnt1-lmx1a Forms a Novel Autoregulatory Loop and Controls Midbrain Dopaminergic Differentiation Synergistically with the SHH-FoxA2 Pathway Sangmi Chung,
IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.
Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.
CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.
Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.
A Conditional Mouse Model for Malignant Mesothelioma Johan Jongsma, Erwin van Montfort, Marc Vooijs, John Zevenhoven, Paul Krimpenfort, Martin van der.
Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar The.
Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.
Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel
Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.
TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype by Evelyn Fessler, Jarno Drost, Sander R van Hooff, Janneke F Linnekamp,
Volume 13, Issue 1, Pages (January 2012)
Cancer: Inappropriate Expression of Stem Cell Programs?
Volume 1, Issue 1, Pages (June 2007)
Stem Cells: All that Is Solid Melts into Air
MDS Is a Stem Cell Disorder After All
DAISY: Picking Synthetic Lethals from Cancer Genomes
Regulating Cancer Stem Cells the miR Way
Jan Philipp Junker, Alexander van Oudenaarden  Molecular Cell 
MicroRNAs and Parallel Stem Cell Lives
Copyright © 2012, Elsevier Inc. All rights Reserved.
Volume 18, Issue 2, Pages (February 2016)
Volume 13, Issue 3, Pages (October 2015)
Copyright © 2013 Elsevier Inc. All rights reserved.
Copyright © 2012, Elsevier Inc. All rights Reserved.
Volume 135, Issue 1, Pages (July 2008)
Volume 68, Issue 5, Pages (November 2005)
NO Signals from the Cancer Stem Cell Niche
Stem Cells: All that Is Solid Melts into Air
Learning from the Uncontrollable
Copyright © 2013 Elsevier Inc. All rights reserved.
To Infinium, and Beyond! Cancer Cell
Volume 10, Issue 3, Pages (September 2006)
Volume 163, Issue 4, (November 2015)
Copyright © 2012, Elsevier Inc. All rights Reserved.
Chapter 29 - Stem Cells and Generation of New Cells in the
Volume 9, Issue 5, Pages (November 2011)
Ibrutinib Treatment of CLL: The Cancer Fights Back
Presentation transcript:

Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients Felipe de Sousa E Melo, Selcuk Colak, Joyce Buikhuisen, Jan Koster, Kate Cameron, Joan H. de Jong, Jurriaan B. Tuynman, Pramudita R. Prasetyanti, Evelyn Fessler, Saskia P. van den Bergh, Hans Rodermond, Evelien Dekker, Chris M. van der Loos, Steven T. Pals, Marc J. van de Vijver, Rogier Versteeg, Dick J. Richel, Louis Vermeulen, Jan Paul Medema Cell Stem Cell Volume 9, Issue 5, Pages (November 2011) DOI: /j.stem Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 1 Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 2 Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 3 Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 4 Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions

Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions