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Stem Cells: All that Is Solid Melts into Air

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1 Stem Cells: All that Is Solid Melts into Air
Maartje van der Heijden, Louis Vermeulen  Cell Stem Cell  Volume 21, Issue 1, Pages 5-7 (July 2017) DOI: /j.stem Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Dynamic Chromatin Remodeling Underlies Intestinal Plasticity
Left: during homeostasis, ISCs and enterocyte progenitors display similar chromatin accessibility profiles, which are clearly distinct from the secretory (progenitor) cells. Right: following ISC loss, precursors of both lineages can rapidly repopulate the ISC compartment, and secretory lineage committed cells display dramatic chromatin remodeling to again adopt an ISC profile. Cell Stem Cell  , 5-7DOI: ( /j.stem ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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